Research output per year
Research output per year
- 1 - 50 out of 97 results
Search results
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2024
HMGB1 in the interplay between autophagy and apoptosis in cancer
Chen, R., Zou, J., Zhong, X., Li, J., Kang, R. & Tang, D., Jan 28 2024, In: Cancer Letters. 581, 216494.Research output: Contribution to journal › Article › peer-review
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2023
ACSS2-mediated NF-κB activation promotes alkaliptosis in human pancreatic cancer cells
Que, D., Kuang, F., Kang, R., Tang, D. & Liu, J., Dec 2023, In: Scientific reports. 13, 1, 1483.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Activating an Adaptive Immune Response with a Telomerase-Mediated Telomere Targeting Therapeutic in Hepatocellular Carcinoma
Mender, I., Siteni, S., Barron, S., Flusche, A. M., Kubota, N., Yu, C., Cornelius, C., Tedone, E., Maziveyi, M., Grichuk, A., Venkateswaran, N., Conacci-Sorrell, M., Hoshida, Y., Kang, R., Tang, D., Gryaznov, S. & Shay, J. W., Jun 1 2023, In: Molecular Cancer Therapeutics. 22, 6, p. 737-750 14 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
ATP6V0D1 promotes alkaliptosis by blocking STAT3-mediated lysosomal pH homeostasis
Chen, F., Zhu, S., Kang, R., Tang, D. & Liu, J., Jan 31 2023, In: Cell Reports. 42, 1, 111911.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Bilirubin inhibits lung carcinogenesis by up-regulating cystatin A expression in tumor-infiltrating macrophages
Huang, Q., Zhang, N., Wang, J., Xu, H., Yao, L., Yang, Q., Yan, D., Chen, X., Xue, Q., Xiao, M., Wu, J., Wu, X., Liu, Q., Tang, D., Chen, X., Li, X. & Liu, J., Nov 2023, In: Genes and Diseases. 10, 6, p. 2222-2225 4 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Copper-dependent autophagic degradation of GPX4 drives ferroptosis
Xue, Q., Yan, D., Chen, X., Li, X., Kang, R., Klionsky, D. J., Kroemer, G., Chen, X., Tang, D. & Liu, J., 2023, In: Autophagy. 19, 7, p. 1982-1996 15 p.Research output: Contribution to journal › Article › peer-review
Open Access79 Scopus citations -
EP300 promotes ferroptosis via HSPA5 acetylation in pancreatic cancer
Wang, Y., Liu, Y., Wang, C., Kang, R., Tang, D. & Liu, J., Dec 2023, In: Scientific reports. 13, 1, 15004.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Extracellular SQSTM1 exacerbates acute pancreatitis by activating autophagy-dependent ferroptosis
Yang, L., Ye, F., Liu, J., Klionsky, D. J., Tang, D. & Kang, R., 2023, In: Autophagy. 19, 6, p. 1733-1744 12 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Identification and characterization of the CDK1-BMAL1-UHRF1 pathway driving tumor progression
Wang, D., Wang, F., Wang, S., Chu, L., Tang, D., Chen, P. & Yang, M., Apr 21 2023, In: iScience. 26, 4, 106544.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Identification of HPCAL1 as a specific autophagy receptor involved in ferroptosis
Chen, X., Song, X., Li, J., Zhang, R., Yu, C., Zhou, Z., Liu, J., Liao, S., Klionsky, D. J., Kroemer, G., Liu, J., Tang, D. & Kang, R., 2023, In: Autophagy. 19, 1, p. 54-74 21 p.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
Inhibition of the SLC35B2–TPST2 Axis of Tyrosine Sulfation Attenuates the Growth and Metastasis of Pancreatic Ductal Adenocarcinom
Cai, X., Li, S., Zeng, X., Xu, M., Wang, Z., Singhi, A. D., Tang, D., Li, S., Yates, N. A., Yang, D. & Xie, W., Jan 2023, In: CMGH. 16, 3, p. 473-495 23 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Neddylation of HER2 Inhibits its Protein Degradation and promotes Breast Cancer Progression
Xia, X., Hu, T., He, X., Liu, Y., Yu, C., Kong, W., Liao, Y., Tang, D., Liu, J. & Huang, H., 2023, In: International Journal of Biological Sciences. 19, 2, p. 377-392 16 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Nuclear localization of STING1 competes with canonical signaling to activate AHR for commensal and intestinal homeostasis
Zhang, R., Yu, C., Zeh, H. J., Wang, H., Kroemer, G., Klionsky, D. J., Billiar, T. R., Kang, R. & Tang, D., Dec 12 2023, In: Immunity. 56, 12, p. 2736-2754.e8Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Plumbagin is a novel GPX4 protein degrader that induces apoptosis in hepatocellular carcinoma cells
Yao, L., Yan, D., Jiang, B., Xue, Q., Chen, X., Huang, Q., Qi, L., Tang, D., Chen, X. & Liu, J., Jul 2023, In: Free Radical Biology and Medicine. 203, p. 1-10 10 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
SLC25A22 as a Key Mitochondrial Transporter Against Ferroptosis by Producing Glutathione and Monounsaturated Fatty Acids
Liu, Y., Wang, Y., Lin, Z., Kang, R., Tang, D. & Liu, J., Jul 1 2023, In: Antioxidants and Redox Signaling. 39, 1-3, p. 166-185 20 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
SQSTM1 is a therapeutic target for infection and sterile inflammation
Tang, D. & Kang, R., Sep 2023, In: Cytokine. 169, 156317.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Targeting proteasomal deubiquitinases USP14 and UCHL5 with b-AP15 reduces 5-fluorouracil resistance in colorectal cancer cells
Ding, W., Wang, J. X., Wu, J. Z., Liu, A. C., Jiang, L. L., Zhang, H. C., Meng, Y., Liu, B. Y., Peng, G. J., Lou, E. Z., Mao, Q., Zhou, H., Tang, D. L., Chen, X., Liu, J. B. & Shi, X. P., Dec 2023, In: Acta Pharmacologica Sinica. 44, 12, p. 2537-2548 12 p.Research output: Contribution to journal › Article › peer-review
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TMEM164 is a new determinant of autophagy-dependent ferroptosis
Liu, J., Liu, Y., Wang, Y., Li, C., Xie, Y., Klionsky, D. J., Kang, R. & Tang, D., 2023, In: Autophagy. 19, 3, p. 945-956 12 p.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
Tumor-specific GPX4 degradation enhances ferroptosis-initiated antitumor immune response in mouse models of pancreatic cancer
Li, J., Liu, J., Zhou, Z., Wu, R., Chen, X., Yu, C., Stockwell, B., Kroemer, G., Kang, R. & Tang, D., Nov 1 2023, In: Science translational medicine. 15, 720, eadg3049.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
TXNDC12 inhibits lipid peroxidation and ferroptosis
Tang, L., Yu, Y., Deng, W., Liu, J., Wang, Y., Ye, F., Kang, R., Tang, D. & He, Q., Dec 15 2023, In: iScience. 26, 12, 108393.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Upstream open reading frames mediate autophagy-related protein translation
Yang, Y., Gatica, D., Liu, X., Wu, R., Kang, R., Tang, D. & Klionsky, D. J., 2023, In: Autophagy. 19, 2, p. 457-473 17 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2022
Aconitate decarboxylase 1 is a mediator of polymicrobial sepsis
Wu, R., Liu, J., Wang, N., Zeng, L., Yu, C., Chen, F., Wang, H., Billiar, T. R., Jiang, J., Tang, D. & Kang, R., Aug 24 2022, In: Science translational medicine. 14, 659, abo2028.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
A noncanonical function of EIF4E limits ALDH1B1 activity and increases susceptibility to ferroptosis
Chen, X., Huang, J., Yu, C., Liu, J., Gao, W., Li, J., Song, X., Zhou, Z., Li, C., Xie, Y., Kroemer, G., Liu, J., Tang, D. & Kang, R., Dec 2022, In: Nature communications. 13, 1, 6318.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
AUF1 protects against ferroptosis to alleviate sepsis-induced acute lung injury by regulating NRF2 and ATF3
Wang, Y., Chen, D., Xie, H., Jia, M., Sun, X., Peng, F., Guo, F. & Tang, D., May 2022, In: Cellular and Molecular Life Sciences. 79, 5, 228.Research output: Contribution to journal › Article › peer-review
33 Scopus citations -
Bilirubin inhibits the anticancer activity of sorafenib by blocking MCL-1 degradation in hepatocellular carcinoma cells
Yao, L., Zhao, Q., Yan, D., Lei, Z., Hao, Y., Chen, J., Xue, Q., Li, X., Huang, Q., Tang, D., Dou, Q. P., Chen, X. & Liu, J., Jul 15 2022, In: Cancer Biology and Medicine. 19, 7, p. 1061-1077 17 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Bispecific T cell engagers kill resistant cells during KRAS-G12C blockade therapy
Song, X., Zhou, Z., Kang, R. & Tang, D., 2022, In: OncoImmunology. 11, 1, 2141978.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Cuproptosis: a copper-triggered modality of mitochondrial cell death
Tang, D., Chen, X. & Kroemer, G., 2022, (Accepted/In press) In: Cell Research.Research output: Contribution to journal › Article › peer-review
Open Access318 Scopus citations -
Cyclophosphamide-induced GPX4 degradation triggers parthanatos by activating AIFM1
Liu, L., Liu, B., Guan, G., Kang, R., Dai, Y. & Tang, D., May 28 2022, In: Biochemical and Biophysical Research Communications. 606, p. 68-74 7 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
DCN released from ferroptotic cells ignites AGER-dependent immune responses
Liu, J., Zhu, S., Zeng, L., Li, J., Klionsky, D. J., Kroemer, G., Jiang, J., Tang, D. & Kang, R., 2022, In: Autophagy. 18, 9, p. 2036-2049 14 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
Extracellular vesicles-transferred SBSN drives glioma aggressiveness by activating NF-κB via ANXA1-dependent ubiquitination of NEMO
Chen, H., Chen, X., Zhang, Z., Bao, W., Gao, Z., Li, D., Xie, X., Zhou, P., Yang, C., Zhou, Z., Pan, J., Kuang, X., Tang, R., Feng, Z., Zhou, L., Zhu, D., Yang, J., Wang, L., Huang, H., Tang, D., & 2 others, Dec 2 2022, In: Oncogene. 41, 49, p. 5253-5265 13 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Heterodimeric RGD-NGR PET Tracer for the Early Detection of Pancreatic Cancer
Sun, L., Gai, Y., Li, Z., Li, H., Li, J., Muschler, J., Kang, R., Tang, D. & Zeng, D., Aug 2022, In: Molecular Imaging and Biology. 24, 4, p. 580-589 10 p.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
HMGB1 is a mediator of cuproptosis-related sterile inflammation
Liu, J., Liu, Y., Wang, Y., Kang, R. & Tang, D., Sep 21 2022, In: Frontiers in Cell and Developmental Biology. 10, 996307.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
HSP90 Mediates IFNg-Induced Adaptive Resistance to Anti-PD-1 Immunotherapy
Liu, K., Huang, J., Liu, J., Li, C., Kroemer, G., Tang, D. & Kang, R., May 15 2022, In: Cancer research. 82, 10, p. 2003-2018 16 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Induction of autophagy-dependent ferroptosis to eliminate drug-tolerant human retinoblastoma cells
Liu, K., Huang, J., Liu, J., Klionsky, D. J., Kang, R. & Tang, D., Jun 2022, In: Cell Death and Disease. 13, 6, 521.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
Pharmacological characterization of a novel metal-based proteasome inhibitor Na-AuPT for cancer treatment
Xu, D. C., Yang, L., Zhang, P. Q., Yan, D., Xue, Q., Huang, Q. T., Li, X. F., Hao, Y. L., Tang, D. L., Ping Dou, Q., Chen, X. & Liu, J. B., Aug 2022, In: Acta Pharmacologica Sinica. 43, 8, p. 2128-2138 11 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Targeting HSP90 sensitizes pancreas carcinoma to PD-1 blockade
Liu, J., Kang, R., Kroemer, G. & Tang, D., 2022, In: OncoImmunology. 11, 1, 2068488.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
The cGAS-STING pathway connects mitochondrial damage to inflammation in burn-induced acute lung injury in rat
Comish, P. B., Liu, M. M., Huebinger, R., Carlson, D., Kang, R. & Tang, D., Feb 2022, In: Burns. 48, 1, p. 168-175 8 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
The deubiquitinating enzyme STAMBP is a newly discovered driver of triple-negative breast cancer progression that maintains RAI14 protein stability
Yang, Q., Yan, D., Zou, C., Xue, Q., Lin, S., Huang, Q., Li, X., Tang, D., Chen, X. & Liu, J., Nov 2022, In: Experimental and Molecular Medicine. 54, 11, p. 2047-2059 13 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
The lipid flippase SLC47A1 blocks metabolic vulnerability to ferroptosis
Lin, Z., Liu, J., Long, F., Kang, R., Kroemer, G., Tang, D. & Yang, M., Dec 2022, In: Nature communications. 13, 1, 7965.Research output: Contribution to journal › Article › peer-review
Open Access45 Scopus citations -
The STING1-MYD88 complex drives ACOD1/IRG1 expression and function in lethal innate immunity
Chen, F., Wu, R., Liu, J., Kang, R., Li, J. & Tang, D., Jul 15 2022, In: iScience. 25, 7, 104561.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Trypsin-Mediated Sensitization to Ferroptosis Increases the Severity of Pancreatitis in Mice
Liu, K., Liu, J., Zou, B., Li, C., Zeh, H. J., Kang, R., Kroemer, G., Huang, J. & Tang, D., Jan 2022, In: CMGH. 13, 2, p. 483-500 18 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
2021
A new role of GRP75-USP1-SIX1 protein complex in driving prostate cancer progression and castration resistance
Liao, Y., Liu, Y., Shao, Z., Xia, X., Deng, Y., Cai, J., Yao, L., He, J., Yu, C., Hu, T., Sun, W., Liu, F., Tang, D., Liu, J. & Huang, H., Jun 24 2021, In: Oncogene. 40, 25, p. 4291-4306 16 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Bilirubin Restrains the Anticancer Effect of Vemurafenib on BRAF-Mutant Melanoma Cells Through ERK-MNK1 Signaling
Tan, Y., Zhong, X., Wen, X., Yao, L., Shao, Z., Sun, W., Wu, J., Wen, G., Tang, D., Zhang, X., Liao, Y. & Liu, J., Jun 18 2021, In: Frontiers in Oncology. 11, 698888.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
CDK1/2/5 blockade: killing two birds with one stone
Liu, J., Kang, R. & Tang, D., 2021, In: OncoImmunology. 10, 1, 1875612.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
CDK1/2/5 inhibition overcomes IFNG-mediated adaptive immune resistance in pancreatic cancer
Huang, J., Chen, P., Liu, K., Liu, J., Zhou, B., Wu, R., Peng, Q., Liu, Z. X., Li, C., Kroemer, G., Lotze, M., Zeh, H., Kang, R. & Tang, D., May 1 2021, In: Gut. 70, 5, p. 890-899 10 p.Research output: Contribution to journal › Article › peer-review
57 Scopus citations -
Exosomal miR-107 antagonizes profibrotic phenotypes of pericytes by targeting a pathway involving HIF-1α/Notch1/PDGFRβ/YAP1/Twist1 axis in vitro
Wang, Y. C., Xie, H., Zhang, Y. C., Meng, Q. H., Xiong, M. M., Jia, M. W., Peng, F. & Tang, D. L., Feb 2021, In: American Journal of Physiology - Heart and Circulatory Physiology. 320, 2Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Ferroptosis by Lipid Peroxidation: The Tip of the Iceberg?
Chen, X., Kang, R. & Tang, D., Mar 25 2021, In: Frontiers in Cell and Developmental Biology. 9, 646890.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Interplay between MTOR and GPX4 signaling modulates autophagy-dependent ferroptotic cancer cell death
Liu, Y., Wang, Y., Liu, J., Kang, R. & Tang, D., Feb 2021, In: Cancer Gene Therapy. 28, 1-2, p. 55-63 9 p.Research output: Contribution to journal › Article › peer-review
138 Scopus citations -
Itaconic acid induces ferroptosis by activating ferritinophagy
Qu, C., Dai, E., Lai, T., Cao, G., Liu, J., Kang, R., Han, L., Tang, D. & Zhou, D., Dec 17 2021, In: Biochemical and Biophysical Research Communications. 583, p. 56-62 7 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Metabolic checkpoint of ferroptosis resistance
Liu, J., Kang, R. & Tang, D., 2021, In: Molecular and Cellular Oncology. 8, 3, 1901558.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations