Research output per year
Research output per year
- 1 - 50 out of 108 results
Search results
-
2018
Suppression of RGSz1 function optimizes the actions of opioid analgesics by mechanisms that involve the Wnt/β-catenin pathway
Gaspari, S., Purushothaman, I., Cogliani, V., Sakloth, F., Neve, R. L., Howland, D., Ring, R. H., Ross, E. M., Shen, L. & Zachariou, V., Feb 27 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 9, p. E2085-E2094Research output: Contribution to journal › Article › peer-review
Open Access24 Scopus citations -
2017
The binding of activated Gq to phospholipase C- exhibits anomalous affinity
Navaratnarajah, P., Gershenson, A. & Ross, E. M., Oct 6 2017, In: Journal of Biological Chemistry. 292, 40, p. 16787-16801 15 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
2016
Amino acids regulate mTORC1 by an obligate two-step mechanism
Dyachok, J., Earnest, S., Iturraran, E. N., Cobb, M. H. & Ross, E. M., Oct 21 2016, In: Journal of Biological Chemistry. 291, 43, p. 22414-22426 13 p.Research output: Contribution to journal › Article › peer-review
Open Access58 Scopus citations -
Intrinsic Pleckstrin Homology (PH) domain motion in phospholipase C-β exposes a Gβγ protein binding site
Kadamur, G. & Ross, E. M., May 20 2016, In: Journal of Biological Chemistry. 291, 21, p. 11394-11406 13 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
2015
Differential regulation of ERK1/2 and mTORC1 through T1R1/T1R3 in MIN6 cells
Wauson, E. M., Guerra, M. L., Dyachok, J., McGlynn, K., Giles, J., Ross, E. M. & Cobb, M. H., Jul 31 2015, In: Molecular Endocrinology. 29, 8, p. 1114-1122 9 p.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
2012
Activation Biosensor for G Protein-Coupled Receptors: A FRET-Based m1 Muscarinic Activation Sensor That Regulates Gq
Chang, S. & Ross, E. M., Sep 20 2012, In: PloS one. 7, 9, e45651.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
2011
Synergistic Ca2+ responses by Gαi- and Gαq-coupled G-protein-coupled receptors require a single PLCβ isoform that is sensitive to both Gβγ and Gαq
Rebres, R. A., Roach, T. I. A., Fraser, I. D. C., Philip, F., Moon, C., Lin, K. M., Liu, J., Santat, L., Cheadle, L., Ross, E. M., Simon, M. I. & Seaman, W. E., Jan 14 2011, In: Journal of Biological Chemistry. 286, 2, p. 942-951 10 p.Research output: Contribution to journal › Article › peer-review
53 Scopus citations -
WNK1 promotes PIP2 synthesis to coordinate growth factor and GPCR-Gq signaling
An, S. W., Cha, S. K., Yoon, J., Chang, S., Ross, E. M. & Huang, C. L., Dec 6 2011, In: Current Biology. 21, 23, p. 1979-1987 9 p.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
2010
Synergistic activation of phospholipase C-β3 by Gαq and Gβγ describes a simple two-state coincidence detector
Philip, F., Kadamur, G., Silos, R. G., Woodson, J. & Ross, E. M., Aug 10 2010, In: Current Biology. 20, 15, p. 1327-1335 9 p.Research output: Contribution to journal › Article › peer-review
68 Scopus citations -
2008
Coordinate regulation of G protein signaling via dynamic interactions of receptor and GAP
Turcotte, M., Tang, W. & Ross, E. M., Aug 2008, In: PLoS Computational Biology. 4, 8, e1000148.Research output: Contribution to journal › Article › peer-review
39 Scopus citations -
2007
Use of a cAMP BRET sensor to characterize a novel regulation of cAMP by the sphingosine 1-phosphate/G13 pathway
Jiang, L. I., Collins, J., Davis, R., Lin, K. M., DeCamp, D., Roach, T., Hsueh, R., Rebres, R. A., Ross, E. M., Taussig, R., Fraser, I. & Sternweis, P. C., Apr 6 2007, In: Journal of Biological Chemistry. 282, 14, p. 10576-10584 9 p.Research output: Contribution to journal › Article › peer-review
276 Scopus citations -
2006
Gβγinhibits Gα GTPase-activating proteins by inhibition of Gα-GTP binding during stimulation by receptor
Tang, W., Tu, Y., Nayak, S. K., Woodson, J., Jehl, M. & Ross, E. M., Feb 24 2006, In: Journal of Biological Chemistry. 281, 8, p. 4746-4753 8 p.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
Structural determinants for phosphatidic acid regulation of phospholipase C-β1
Ross, E. M., Mateu, D., Gomes, A. V., Arana, C., Tran, T. & Litosch, I., Nov 3 2006, In: Journal of Biological Chemistry. 281, 44, p. 33087-33094 8 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
2005
Q & A. Elliott Ross.
Ross, E., Dec 6 2005, In: Current biology : CB. 15, 23, p. R942-943Research output: Contribution to journal › Article › peer-review
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Spinophilin regulates Ca2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors
Wang, X., Zeng, W., Syombo, A. A., Tang, W., Ross, E. M., Barnes, A. P., Milgram, S. L., Penninger, J. M., Allen, P. B., Greengard, P. & Muallem, S., Apr 2005, In: Nature cell biology. 7, 4, p. 405-411 7 p.Research output: Contribution to journal › Article › peer-review
131 Scopus citations -
2004
Uncoupling conformational change from GTP hydrolysis in a heterotrimetric G protein α-subunit
Thomas, C. J., Du, X., Li, P., Wang, Y., Ross, E. M. & Sprang, S. R., May 18 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 20, p. 7560-7565 6 p.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
2003
Homer 2 tunes G protein-coupled receptors stimulus intensity by regulating RGS proteins and PLCβ GAP activities
Shin, D. M., Dehoff, M., Luo, X., Kang, S. H., Tu, J., Nayak, S. K., Ross, E. M., Worley, P. E. & Muallem, S., Jul 21 2003, In: Journal of Cell Biology. 162, 2, p. 293-303 11 p.Research output: Contribution to journal › Article › peer-review
80 Scopus citations -
Phosphorylation-regulated Inhibition of the Gz GTPase-activating Protein Activity of RGS Proteins by Synapsin I
Tu, Y., Nayak, S. K., Woodson, J. & Ross, E. M., Dec 26 2003, In: Journal of Biological Chemistry. 278, 52, p. 52273-52281 9 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
2002
Mutations in the carboxyl-terminal domain of phospholipase C-β1 delineate the dimer interface and a potential Gαq interaction site
Ilkaeva, O., Kinch, L. N., Paulssen, R. H. & Ross, E. M., Feb 8 2002, In: Journal of Biological Chemistry. 277, 6, p. 4294-4300 7 p.Research output: Contribution to journal › Article › peer-review
54 Scopus citations -
2001
Binding of regulator of G protein signaling (RGS) proteins to phospholipid bilayers. Contribution of location and/or orientation to GTPase-activating protein activity
Tu, Y., Woodson, J. & Ross, E. M., Jun 8 2001, In: Journal of Biological Chemistry. 276, 23, p. 20160-20166 7 p.Research output: Contribution to journal › Article › peer-review
53 Scopus citations -
Quantitative assays for GTPase-activating proteins
Ross, E. M., 2001, In: Methods in Enzymology. 344, p. 601-617 17 p.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
Quench-flow kinetic measurement of individual reactions of G-protein-catalyzed GTPase cycle
Mukhopadhyay, S. & Ross, E. M., 2001, In: Methods in Enzymology. 344, p. 350-369 20 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
RGSZ1 and Ret RGS: Two of several splice variants from the gene RGS20
Barker, S. A., Wang, J., Sierra, D. A. & Ross, E. M., Dec 2001, In: Genomics. 78, 3, p. 223-229 7 p.Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
1999
Kinetic control of guanine nucleotide binding to soluble Gα(q)
Markin, V. S. & Ross, E. M., Jul 1 1999, In: Biochemical Pharmacology. 58, 1, p. 39-48 10 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
Modulation of the affinity and selectivity of RGS protein interaction with Gα subunits by a conserved asparagine/serine residue
Posner, B. A., Mukhopadhyay, S., Tesmer, J. J., Gilman, A. G. & Ross, E. M., Jun 15 1999, In: Biochemistry. 38, 24, p. 7773-7779 7 p.Research output: Contribution to journal › Article › peer-review
70 Scopus citations -
Palmitoylation of a conserved cysteine in the regulator of G protein signaling (RGS) domain modulates the GTPase-activating activity of RGS4 and RGS10
Tu, Y., Popov, S., Slaughter, C. & Ross, E. M., Dec 31 1999, In: Journal of Biological Chemistry. 274, 53, p. 38260-38267 8 p.Research output: Contribution to journal › Article › peer-review
91 Scopus citations -
Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins
Mukhopadhyay, S. & Ross, E. M., Aug 17 1999, In: Proceedings of the National Academy of Sciences of the United States of America. 96, 17, p. 9539-9544 6 p.Research output: Contribution to journal › Article › peer-review
Open Access159 Scopus citations -
Reciprocal signaling between heterotrimeric G proteins and the p21- stimulated protein kinase
Wang, J., Frost, J. A., Cobb, M. H. & Ross, E. M., Oct 29 1999, In: Journal of Biological Chemistry. 274, 44, p. 31641-31647 7 p.Research output: Contribution to journal › Article › peer-review
55 Scopus citations -
1998
Dynamic regulation of RGS2 suggests a novel mechanism in G-protein signaling and neuronal plasticity
Ingi, T., Krumins, A. M., Chidiac, P., Brothers, G. M., Chung, S., Snow, B. E., Barnes, C. A., Lanahan, A. A., Siderovski, D. P., Ross, E. M., Gilman, A. G. & Worley, P. F., Sep 15 1998, In: Journal of Neuroscience. 18, 18, p. 7178-7188 11 p.Research output: Contribution to journal › Article › peer-review
Open Access270 Scopus citations -
RGSZ1, a G(z)-selective rgs protein in brain: Structure, membrane association, regulation by Gα(z) phosphorylation, and relationship to a G(z) gtpase-activating protein subfamily
Wang, J., Ducret, A., Tu, Y., Kozasa, T., Aebersold, R. & Ross, E. M., Oct 2 1998, In: Journal of Biological Chemistry. 273, 40, p. 26014-26025 12 p.Research output: Contribution to journal › Article › peer-review
137 Scopus citations -
The N-terminal domain of RGS4 confers receptor-selective inhibition of G protein signaling
Zeng, W., Xu, X., Popov, S., Mukhopadhyay, S., Chidiac, P., Swistok, J., Danho, W., Yagaloff, K. A., Fisher, S. L., Ross, E. M., Muallem, S. & Wilkie, T. M., Dec 25 1998, In: Journal of Biological Chemistry. 273, 52, p. 34687-34690 4 p.Research output: Contribution to journal › Article › peer-review
221 Scopus citations -
1997
A G(s)-selective analog of the receptor-mimetic peptide mastoparan binds to G(s)α in a kinked helical conformation
Sukumar, M., Ross, E. M. & Higashijima, T., Mar 25 1997, In: Biochemistry. 36, 12, p. 3632-3639 8 p.Research output: Contribution to journal › Article › peer-review
34 Scopus citations -
A GTPase-activating protein for the G protein Gα(z). Identification, purification, and mechanism of action
Wang, J., Tu, Y., Woodson, J., Song, X. & Ross, E. M., Feb 28 1997, In: Journal of Biological Chemistry. 272, 9, p. 5732-5740 9 p.Research output: Contribution to journal › Article › peer-review
65 Scopus citations -
Colloquium on signaling and molecular structure in pharmacology (La Jolla, California, March 11-12, 1997)
Taylor, P., Ross, E. M., Sternweis, P. C., Neubig, R. R. & McCammon, J. A., 1997, In: Molecular Pharmacology. 52, 1, p. 1-5 5 p.Research output: Contribution to journal › Article › peer-review
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Expression of human muscarinic cholinergic receptors in tobacco
Mu, J. H., Chua, N. H. & Ross, E. M., May 1997, In: Plant Molecular Biology. 34, 2, p. 357-362 6 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Guanosine Triphosphatase-Activating Proteins for Heterotrimeric G-Proteins
Ross, E. M., Wang, J., Tu, Y. & Biddlecome, G. H., 1997, In: Advances in Pharmacology. 42, C, p. 458-461 4 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Inhibition of brain G(z) GAP and other RGS proteins by palmitoylation of G protein α subunits
Tu, Y., Wang, J. & Ross, E. M., Nov 7 1997, In: Science. 278, 5340, p. 1132-1135 4 p.Research output: Contribution to journal › Article › peer-review
130 Scopus citations -
1996
Carboxyl-terminal fragments of phospholipase C-β1 with intrinsic G(q) GTPase-activating protein (GAP) activity
Paulssen, R. H., Woodson, J., Liu, Z. & Ross, E. M., 1996, In: Journal of Biological Chemistry. 271, 43, p. 26622-26629 8 p.Research output: Contribution to journal › Article › peer-review
59 Scopus citations -
Functional importance of the amino terminus of Gqα
Hepler, J. R., Biddlecome, G. H., Kleuss, C., Camp, L. A., Hofmann, S. L., Ross, E. M. & Gilman, A. G., Jan 5 1996, In: Journal of Biological Chemistry. 271, 1, p. 496-504 9 p.Research output: Contribution to journal › Article › peer-review
Open Access101 Scopus citations -
Purification and characterization of phospholipase C-β1 mutants expressed in E. coli
Meij, J. T. A. & Ross, E. M., Aug 23 1996, In: Biochemical and Biophysical Research Communications. 225, 3, p. 705-711 7 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Regulation of phospholipase C-β1 by Gq and m1 muscarinic cholinergic receptor: Steady-state balance of receptor-mediated activation and GTPase-activating protein-promoted deactivation
Biddlecome, G. H., Berstein, G. & Ross, E. M., Apr 5 1996, In: Journal of Biological Chemistry. 271, 14, p. 7999-8007 9 p.Research output: Contribution to journal › Article › peer-review
Open Access213 Scopus citations -
1995
Carboxyl-terminal domains in the avian β1-adrenergic receptor that regulate agonist-promoted endocytosis
Parker, E. M., Swigart, P., Nunnally, M. H., Perkins, J. P. & Ross, E. M., Mar 24 1995, In: Journal of Biological Chemistry. 270, 12, p. 6482-6487 6 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
G protein GTPase-activating proteins: Regulation of speed, amplitude, and signaling selectivity
Ross, E. M., 1995, In: Recent progress in hormone research. 50, 1, p. 207-221 15 p.Research output: Contribution to journal › Article › peer-review
42 Scopus citations -
Protein Modification: Palmitoylation in G-protein signaling pathways
Ross, E. M., Feb 1995, In: Current Biology. 5, 2, p. 107-109 3 p.Research output: Contribution to journal › Article › peer-review
75 Scopus citations -
The carboxyl-terminal anchorage domain of the Turkey β1-adrenergic receptor is encoded by an alternatively spliced exon
Wang, J. & Ross, E. M., Mar 24 1995, In: Journal of Biological Chemistry. 270, 12, p. 6488-6495 8 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
1994
Chimeric muscarinic cholinergic:β-adrenergic receptors that are functionally promiscuous among G proteins
Wong, S. K. F. & Ross, E. M., Jul 22 1994, In: Journal of Biological Chemistry. 269, 29, p. 18968-18976 9 p.Research output: Contribution to journal › Article › peer-review
74 Scopus citations -
Gs Regulation of Endosome Fusion Suggests a Role for Signal Transduction Pathways in Endocytosis
Colombo, M. I., Mayorga, L. S., Nishimoto, I., Ross, E. M. & Stahl, P. D., May 27 1994, In: Journal of Biological Chemistry. 269, 21, p. 14919-14923 5 p.Research output: Contribution to journal › Article › peer-review
55 Scopus citations -
Regulation of G-protein activation by mastoparans and other cationic peptides
Ross, E. M. & Higashijima, T., Jan 1 1994, In: Methods in Enzymology. 237, C, p. 26-37 12 p.Research output: Contribution to journal › Article › peer-review
98 Scopus citations -
1993
GAP-43 augments G protein-coupled receptor transduction in Xenopus laevis oocytes
Strittmatter, S. M., Cannon, S. C., Ross, E. M., Higashijima, T. & Fishman, M. C., Jun 1 1993, In: Proceedings of the National Academy of Sciences of the United States of America. 90, 11, p. 5327-5331 5 p.Research output: Contribution to journal › Article › peer-review
71 Scopus citations -
Regulation of the M1 muscarinic receptor-Gg-phospholipase C-β pathway by nucleotide exchange and GTP hydrolysis
Ross, E. M. & Berstein, G., 1993, In: Life Sciences. 52, 5-6, p. 413-419 7 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations