Pharmacology - Corey Lab

Research output

Research output per year 1985 1995 1997 1999 2001 2002 2003 2004 2005 2006 2007 2009 2010 2011 2012 2014 2015 2016 2020 2024

• 174 Article
• 23 Review article
• 5 Short survey
• 4 Chapter
• 9 More
  • 4 Comment/debate
  • 3 Editorial
  • 1 Conference contribution
  • 1 Letter

Research output per year

Research output per year

Search results

• 2003

  Binding of nonphysiological protein and peptide substrates to proteases: Differences between urokinase-type plasminogen activator and trypsin and contributions to the evolution of regulated proteolysis

  Bergstrom, R. C., Coombs, G. S., Ye, S., Madison, E. L., Goldsmith, E. J. & Corey, D. R., May 13 2003, In: Biochemistry. 42, 18, p. 5395-5402 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Urokinase-Type Plasminogen Activator 100%
  • Protein Hydrolysis 95%
  • Trypsin 89%
  • Proteolysis 82%
  • Carrier Proteins 74%
  6 Scopus citations

• Consequences of telomerase inhibition and combination treatments for the proliferation of cancer cells

  Chen, Z., Koeneman, K. S. & Corey, D. R., Sep 15 2003, In: Cancer research. 63, 18, p. 5917-5925 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Telomerase 100%
  • Cell Proliferation 57%
  • Telomere Shortening 43%
  • Neoplasms 28%
  • Carboplatin 24%
  75 Scopus citations

• Extending Recognition by Peptide Nucleic Acids (PNAs): Binding to Duplex DNA and Inhibition of Transcription by Tail-Clamp PNA-Peptide Conjugates

  Kaihatsu, K., Shah, R. H., Zhao, X. & Corey, D. R., Dec 2 2003, In: Biochemistry. 42, 47, p. 13996-14003 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptide Nucleic Acids 100%
  • Peptide Nucleic Acid 85%
  • Peptides 43%
  • Peptide 39%
  • DNA 37%
  71 Scopus citations

• Inhibition of telomerase by BIBR 1532 and related analogues

  Barma, D. K., Elayadi, A., Falck, J. R. & Corey, D. R., Apr 7 2003, In: Bioorganic and Medicinal Chemistry Letters. 13, 7, p. 1333-1336 4 p.

  Research output: Contribution to journal › Article › peer-review

  • BIBR 1532 100%
  • Telomerase 56%
  • Enzyme Assays 18%
  • Cell Extracts 17%
  • Molecule 17%
  43 Scopus citations

• Inhibition of transcription by bisPNA-peptide conjugates

  Zhao, X., Kaihatsu, K. & Corey, D. R., 2003, In: Nucleosides, Nucleotides and Nucleic Acids. 22, 5-8, p. 535-546 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptides 100%
  • Peptide 90%
  • DNA 58%
  • Double-Stranded DNA 55%
  • Magnesium 52%
  5 Scopus citations

• RNA interference in mammalian cells by chemically-modified RNA

  Braasch, D. A., Jensen, S., Liu, Y., Kaur, K., Arar, K., White, M. A. & Corey, D. R., Jul 8 2003, In: Biochemistry. 42, 26, p. 7967-7975 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Mammalian Cell 100%
  • Locked Nucleic Acid 95%
  • RNA Interference 92%
  • RNA 66%
  • Modification 53%
  501 Scopus citations

• The synaptic complex of RecA protein participates in hybridization and inverse strand exchange reactions

  Gamper, H. B., Nulf, C. J., Corey, D. R. & Kmiec, E. B., Mar 11 2003, In: Biochemistry. 42, 9, p. 2643-2655 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Rec A Recombinases 100%
  • Oligonucleotides 68%
  • Oligonucleotide 58%
  • Protein 27%
  • Deoxyribose 25%
  7 Scopus citations

• Transcription activation by a PNA-Peptide chimera in a mammalian cell extract

  Liu, B., Han, Y., Ferdous, A., Corey, D. R. & Kodadek, T., Oct 2003, In: Chemistry and Biology. 10, 10, p. 909-916 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptide Nucleic Acids 100%
  • Peptide Nucleic Acid 85%
  • Cell Extracts 72%
  • Mammalian Cell 70%
  • Transcriptional Activation 61%
  32 Scopus citations
• 2002

  Cellular delivery of locked nucleic acids (LNAs).

  Braasch, D. A. & Corey, D. R., Aug 2002, In: Current protocols in nucleic acid chemistry / edited by Serge L. Beaucage ... [et al.]. Chapter 4, p. Unit 4.13

  Research output: Contribution to journal › Article › peer-review

  • locked nucleic acid 100%
  • Locked Nucleic Acid 96%
  • Oligomer 34%
  • RNA 30%
  • Ribose 29%
  2 Scopus citations

• DNA assembly using bis-peptide nucleic acids (bisPNAs)

  Nulf, C. J. & Corey, D. R., Jul 1 2002, In: Nucleic acids research. 30, 13, p. 2782-2789 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Peptide Nucleic Acids 100%
  • Oligonucleotides 39%
  • DNA 37%
  • Nanostructures 17%
  • Molecular Computers 12%
  10 Scopus citations

• Enhanced strand invasion by peptide nucleic acid-peptide conjugates

  Kaihatsu, K., Braasch, D. A., Cansizoglu, A. & Corey, D. R., Sep 17 2002, In: Biochemistry. 41, 37, p. 11118-11125 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptide Nucleic Acids 100%
  • Peptide Nucleic Acid 85%
  • Peptides 43%
  • Peptide 39%
  • DNA-Binding Proteins 25%
  41 Scopus citations

• Imaging gene expression in the brain in vivo in a transgenic mouse model of Huntington's disease with an antisense radiopharmaceutical and drug-targeting technology

  Lee, H. J., Boado, R. J., Braasch, D. A., Corey, D. R. & Pardridge, W. M., Jul 20 2002, In: Journal of Nuclear Medicine. 43, 7, p. 948-956 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptide Nucleic Acids 100%
  • Radiopharmaceuticals 81%
  • Huntington Disease 75%
  • Drug Delivery Systems 66%
  • Transgenic Mice 60%
  64 Scopus citations

• Implications of high-affinity hybridization by locked nucleic acid oligomers for inhibition of human telomerase

  Elayadi, A. N., Braasch, D. A. & Corey, D. R., Aug 6 2002, In: Biochemistry. 41, 31, p. 9973-9981 9 p.

  Research output: Contribution to journal › Article › peer-review

  • locked nucleic acid 100%
  • Locked Nucleic Acid 96%
  • Telomerase 73%
  • Oligonucleotide 57%
  • Oligomer 51%
  95 Scopus citations

• Lipid-mediated introduction of peptide nucleic acids into cells.

  Braasch, D. A. & Corey, D. R., 2002, In: Methods in molecular biology (Clifton, N.J.). 208, p. 211-223 13 p.

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• Non-Watson-Crick interactions between PNA and DNA inhibit the ATPase activity of bacteriophage T4 Dda helicase

  Tackett, A. J., Corey, D. R. & Raney, K. D., Feb 15 2002, In: Nucleic acids research. 30, 4, p. 950-957 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Peptide Nucleic Acids 100%
  • Bacteriophage T4 92%
  • Adenosine Triphosphatases 67%
  • Single-Stranded DNA 52%
  • DNA 37%
  45 Scopus citations

• Novel antisense and peptide nucleic acid strategies for controlling gene expression

  Braasch, D. A. & Corey, D. R., Apr 9 2002, In: Biochemistry. 41, 14, p. 4503-4510 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptide Nucleic Acids 100%
  • Peptide Nucleic Acid 85%
  • Oligonucleotides 70%
  • Oligonucleotide 59%
  • Oligomer 53%
  242 Scopus citations

• Synthesis and purification of peptide nucleic acids.

  Braasch, D. A., Nulf, C. J. & Corey, D. R., Aug 2002, In: Current protocols in nucleic acid chemistry / edited by Serge L. Beaucage ... [et al.]. Chapter 4, p. Unit 4.11

  Research output: Contribution to journal › Article › peer-review

  • Peptide Nucleic Acids 100%
  • Peptide Nucleic Acid 85%
  • Purification 45%
  • Peptides 14%
  • Peptide 13%
  13 Scopus citations

• Telomerase-dependent reactivation of DNA synthesis in macrophages implies alteration of telomeres

  Yegorov, Y. E., Kazimirchuk, E. V., Terekhov, S. M., Karachentsev, D. N., Shirokova, E. A., Khandazhinskaya, A. L., Meshcheryakova, J. A., Corey, D. R. & Zelenin, A. V., 2002, In: Cell Biology International. 26, 12, p. 1019-1027 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Telomerase 100%
  • Telomere 96%
  • Macrophages 61%
  • Fibroblasts 52%
  • DNA 49%
  5 Scopus citations

• Telomerase inhibition, telomere shortening, and decreased cell proliferation by cell permeable 2′-O-methoxyethyl oligonucleotides

  Chen, Z., Monia, B. P. & Corey, D. R., Dec 5 2002, In: Journal of Medicinal Chemistry. 45, 25, p. 5423-5425 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Telomere Shortening 100%
  • Telomerase 86%
  • Shortening 84%
  • Oligonucleotides 78%
  • Oligonucleotide 66%
  21 Scopus citations

• Toward synthetic transcription activators: Recruitment of transcription factors to DNA by a PNA-peptide chimera

  Liu, B., Han, Y., Corey, D. R. & Kodadek, T., Mar 6 2002, In: Journal of the American Chemical Society. 124, 9, p. 1838-1839 2 p.

  Research output: Contribution to journal › Article › peer-review

  • Transcription factors 100%
  • Peptides 91%
  • Transcription 80%
  • DNA 71%
  • Transcription Factors 52%
  34 Scopus citations
• 2001

  A bridge between the RNA and protein worlds? Accelerating delivery of chemical reactivity to RNA and DNA by a specific short peptide (AAKK)₄

  Bergstrom, R. C., Mayfield, L. D. & Corey, D. R., 2001, In: Chemistry and Biology. 8, 2, p. 199-205 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Chemical Reactivity 100%
  • RNA 66%
  • Peptides 60%
  • Peptide 55%
  • DNA 53%
  8 Scopus citations

• Engineering orthogonal ligand-receptor pairs from "near drugs"

  Doyle, D. F., Braasch, D. A., Jackson, L. K., Weiss, H. E., Boehm, M. F., Mangelsdorf, D. J. & Corey, D. R., Nov 21 2001, In: Journal of the American Chemical Society. 123, 46, p. 11367-11371 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Ligands 100%
  • Retinoid 49%
  • Cytoplasmic and Nuclear Receptors 47%
  • Drug 39%
  • Hormone 37%
  33 Scopus citations

• Inhibition of gene expression inside cells by peptide nucleic acids: Effect of mRNA target sequence, mismatched bases, and PNA length

  Doyle, D. F., Braasch, D. A., Simmons, C. G., Janowski, B. A. & Corey, D. R., Jan 9 2001, In: Biochemistry. 40, 1, p. 53-64 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptide Nucleic Acids 100%
  • Peptide Nucleic Acid 85%
  • Gene Expression 40%
  • Length 40%
  • Messenger RNA 38%
  137 Scopus citations

• Inhibition of telomerase by 2′-O-(2-methoxyethyl) RNA oligomers: Effect of length, phosphorothioate substitution and time inside cells

  Elayadi, A. N., Demieville, A., Wancewicz, E. V., Monia, B. P. & Corey, D. R., Apr 15 2001, In: Nucleic acids research. 29, 8, p. 1683-1689 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 2'-O-(2-methoxyethyl)-RNA 100%
  • Telomerase 48%
  • Cell Extracts 22%
  • Oligonucleotides 21%
  • Inhibitory Concentration 50 19%
  58 Scopus citations

• Liver cell specific targeting of peptide nucleic acid oligomers

  Zhang, X., Simmons, C. G. & Corey, D. R., May 21 2001, In: Bioorganic and Medicinal Chemistry Letters. 11, 10, p. 1269-1272 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptide Nucleic Acids 100%
  • Peptide Nucleic Acid 85%
  • Lactose 79%
  • Oligomer 53%
  • Liver 34%
  46 Scopus citations

• Synthesis, analysis, purification, and intracellular delivery of peptide nucleic acids

  Braasch, D. A. & Corey, D. R., 2001, In: Methods. 23, 2, p. 97-107 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptide Nucleic Acids 100%
  • Peptide Nucleic Acid 85%
  • Purification 45%
  • Mammalian Cell 23%
  • Cell Culture Techniques 17%
  56 Scopus citations

• The structure of a Michaelis serpin-protease complex

  Ye, S., Cech, A. L., Belmares, R., Bergstrom, R. C., Tong, Y., Corey, D. R., Kanost, M. R. & Goldsmith, E. J., 2001, In: Nature Structural Biology. 8, 11, p. 979-983 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Serine Protease Inhibitor 100%
  • Serine Proteinase Inhibitors 89%
  • Protease Inhibitor 83%
  • Serine 66%
  • Peptide Hydrolases 59%
  148 Scopus citations
• 2000

  Negative selectivity and the evolution of protease cascades: The specificity of plasmin for peptide and protein substrates

  Hervio, L. S., Coombs, G. S., Bergstrom, R. C., Trivedi, K., Corey, D. R. & Madison, E. L., Jun 1 2000, In: Chemistry and Biology. 7, 6, p. 443-452 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Fibrinolysin 100%
  • Peptide Hydrolases 70%
  • Protein Hydrolysis 60%
  • Peptides 53%
  • Peptide 48%
  58 Scopus citations

• Strand invasion by mixed base PNAs and a PNA-peptide chimera

  Zhang, X., Ishihara, T. & Corey, D. R., Sep 1 2000, In: Nucleic acids research. 28, 17, p. 3332-3338 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Peptides 100%
  • DNA 87%
  • Psychology Recognition 69%
  • Plasmids 63%
  • Peptide Nucleic Acids 57%
  67 Scopus citations

• Telomerase: An unusual target for cytotoxic agents

  Corey, D. R., 2000, In: Chemical Research in Toxicology. 13, 10, p. 957-960 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Cytotoxic Agent 100%
  • Telomerase 90%
  • Cytotoxins 89%
  • Oligonucleotide 70%
  • Oligonucleotides 20%
  12 Scopus citations
• 1999

  Automated synthesis of peptide nucleic acids and peptide nucleic acid- peptide conjugates

  Mayfield, L. D. & Corey, D. R., Mar 15 1999, In: Analytical biochemistry. 268, 2, p. 401-404 4 p.

  Research output: Contribution to journal › Article › peer-review
  49 Scopus citations

• Cellular delivery of peptide nucleic acids and inhibition of human telomerase

  Hamilton, S. E., Simmons, C. G., Kathiriya, I. S. & Corey, D. R., Jun 1999, In: Chemistry and Biology. 6, 6, p. 343-351 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptide Nucleic Acids 100%
  • Peptide Nucleic Acid 85%
  • Telomerase 77%
  • telomerase RNA 24%
  • Telomerase Inhibitor 13%
  171 Scopus citations

• Enhancing solid phase synthesis by a noncovalent protection strategy - Efficient coupling of rhodamine to resin-bound peptide nucleic acids

  Mayfield, L. D. & Corey, D. R., May 17 1999, In: Bioorganic and Medicinal Chemistry Letters. 9, 10, p. 1419-1422 4 p.

  Research output: Contribution to journal › Article › peer-review

  • polyethylene glycol-polystyrene 100%
  • Solid-Phase Synthesis Techniques 73%
  • Peptide Nucleic Acids 67%
  • Rhodamines 63%
  • Peptide Nucleic Acid 57%
  19 Scopus citations

• Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

  Herbert, B. S., Pitts, A. E., Baker, S. I., Hamilton, S. E., Wright, W. E., Shay, J. W. & Corey, D. R., Dec 7 1999, In: Proceedings of the National Academy of Sciences of the United States of America. 96, 25, p. 14276-14281 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Telomere Shortening 100%
  • Telomerase 86%
  • Cell Death 57%
  • Peptide Nucleic Acids 18%
  • Telomere 13%
  507 Scopus citations

• Rules for strand invasion by chemically modified oligonucleotides

  Ishihara, T. & Corey, D. R., Mar 17 1999, In: Journal of the American Chemical Society. 121, 10, p. 2012-2020 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptide Nucleic Acids 100%
  • Oligonucleotides 86%
  • Peptide Nucleic Acid 73%
  • DNA 59%
  • Oligonucleotide 51%
  31 Scopus citations

• Strand invasion by DNA-peptide conjugates and peptide nucleic acids.

  Ishihara, T. & Corey, D. R., 1999, In: Nucleic acids symposium series. 42, p. 141-142 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • AT Rich Sequence 100%
  • Peptide Nucleic Acids 96%
  • Oligonucleotides 67%
  • Peptides 41%
  • DNA 36%
  5 Scopus citations

• Telomerase inhibition by peptide nucleic acids reverses 'immortality' of transformed human cells

  Shammas, M. A., Simmons, C. G., Corey, D. R. & Shmookler Reis, R. J., Nov 4 1999, In: Oncogene. 18, 46, p. 6191-6200 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptide Nucleic Acids 100%
  • Telomerase 77%
  • Diploidy 24%
  • Tumor Cell Line 22%
  • Plasmids 18%
  138 Scopus citations
• 1998

  Directing sequence-specific proteolysis to new targets. The influence of loop size and target sequence on selective proteolysis by tissue-type plasminogen activator and urokinase-type plasminogen activator

  Coombs, G. S., Bergstrom, R. C., Madison, E. L. & Corey, D. R., Feb 20 1998, In: Journal of Biological Chemistry. 273, 8, p. 4323-4328 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Plasminogen Activators 100%
  • Urokinase-Type Plasminogen Activator 96%
  • Protein Hydrolysis 91%
  • Tissue Plasminogen Activator 90%
  • Proteolysis 79%
  27 Scopus citations

• Engineering novel specificities for ligand-activated transcription in the nuclear hormone receptor RXR

  Peet, D. J., Doyle, D. F., Corey, D. R. & Mangelsdorf, D. J., Jan 1998, In: Chemistry and Biology. 5, 1, p. 13-21 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Retinoid X Receptors 100%
  • Retinoid 96%
  • Cytoplasmic and Nuclear Receptors 75%
  • Hormone 73%
  • Ligands 51%
  46 Scopus citations

• Inhibition of human telomerase by 2′-O-methyl-RNA

  Pitts, A. E. & Corey, D. R., Sep 29 1998, In: Proceedings of the National Academy of Sciences of the United States of America. 95, 20, p. 11549-11554 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Telomerase 100%
  • Peptide Nucleic Acids 64%
  • RNA 60%
  • Oligonucleotides 22%
  • telomerase RNA 16%
  140 Scopus citations

• Substrate specificity of prostate-specific antigen (PSA)

  Coombs, G. S., Bergstrom, R. C., Pellequer, J. L., Baker, S. I., Navre, M., Smith, M. M., Tainer, J. A., Madison, E. L. & Corey, D. R., Sep 1998, In: Chemistry and Biology. 5, 9, p. 475-488 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Substrate Specificity 100%
  • Prostate-Specific Antigen 91%
  • Antigen 75%
  • Serine Proteases 25%
  • Cleavage 23%
  110 Scopus citations
• 1997

  Distinguishing the specificities of closely related proteases: role of p3 in substrate and inhibitor discrimination between tissue type plasminogen activator and urokinase

  Ke, S. H., Coombs, G. S., Tachias, K., Navre, M., Corey, D. R. & Madison, E. L., 1997, In: Fibrinolysis and Proteolysis. 11, SUPPL. 3, p. 51 1 p.

  Research output: Contribution to journal › Article › peer-review

  • Plasminogen Activators 100%
  • Urokinase-Type Plasminogen Activator 96%
  • Tissue Plasminogen Activator 90%
  • Peptide Hydrolases 71%
  • Plasminogen Activator Inhibitor 1 47%

• Distinguishing the specificities of closely related proteases

  Madison, E. L., Ke, S. H., Coombs, G. S., Corey, D. R. & Navre, M., Dec 1 1997, In: FASEB Journal. 11, 9, p. A1122

  Research output: Contribution to journal › Article › peer-review

  • Molecular Recognition 100%
  • Serine 93%
  • Peptide Hydrolases 83%
  • Drug Design 57%
  • Enzyme Inhibitors 57%

• Distinguishing the specificities of closely related proteases: Role of P3 in substrate and inhibitor discrimination between tissue-type plasminogen activator and urokinase

  Ke, S. H., Coombs, G. S., Tachias, K., Navre, M., Corey, D. R. & Madison, E. L., Jun 27 1997, In: Journal of Biological Chemistry. 272, 26, p. 16603-16609 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Plasminogen Activator Inhibitor 100%
  • Plasminogen Activators 76%
  • Urokinase-Type Plasminogen Activator 74%
  • Tissue Plasminogen Activator 69%
  • Peptide Hydrolases 54%
  55 Scopus citations

• Enhanced hybridization by peptide nucleic acids

  Corey, D. R., Hamilton, S., Simmons, C., Mayfield, L. & Pitts, A., 1997, In: Fibrinolysis and Proteolysis. 11, SUPPL. 3, p. 52 1 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptide Nucleic Acids 100%
  • Solid-Phase Synthesis Techniques 18%
  • Chromosome Mapping 13%
  • Amides 13%
  • DNA 12%

• Identification of determinants for inhibitor binding within the RNA active site of human telomerase using PNA scanning

  Hamilton, S. E., Pitts, A. E., Katipally, R. R., Jia, X., Rutter, J. P., Davies, B. A., Shay, J. W., Wright, W. E. & Corey, D. R., Sep 30 1997, In: Biochemistry. 36, 39, p. 11873-11880 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptide Nucleic Acids 100%
  • Peptide Nucleic Acid 85%
  • Telomerase 77%
  • Catalytic Domain 60%
  • RNA 46%
  86 Scopus citations

• Optimal subsite occupancy and design of a selective inhibitor of urokinase

  Ke, S. H., Coombs, G. S., Tachias, K., Corey, D. R. & Madison, E. L., Aug 15 1997, In: Journal of Biological Chemistry. 272, 33, p. 20456-20462 7 p.

  Research output: Contribution to journal › Article › peer-review

  • urokinase inhibitor 100%
  • Urokinase-Type Plasminogen Activator 64%
  • Peptide 32%
  • Peptides 25%
  • Plasminogen Activators 19%
  102 Scopus citations

• Peptide nucleic acids: Expanding the scope of nucleic acid recognition

  Corey, D. R., Jun 1997, In: Trends in Biotechnology. 15, 6, p. 224-229 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Peptide Nucleic Acids 100%
  • Nucleic acids 67%
  • Peptide Nucleic Acid 58%
  • Nucleic Acids 45%
  • Nucleic Acid 39%
  104 Scopus citations

• Synthesis and membrane permeability of PNA-peptide conjugates

  Simmons, C. G., Pitts, A. E., Mayfield, L. D., Shay, J. W. & Corey, D. R., Dec 2 1997, In: Bioorganic and Medicinal Chemistry Letters. 7, 23, p. 3001-3006 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Permeability 100%
  • Peptide Nucleic Acids 85%
  • Peptides 74%
  • Peptide Nucleic Acid 73%
  • Membranes 69%
  100 Scopus citations

• Targeting proteolysis to non-physiological protein substrates

  Corey, D. R., Coombs, G. S., Bergstrom, R. C. & Madison, E. L., 1997, In: Fibrinolysis and Proteolysis. 11, SUPPL. 3, p. 51 1 p.

  Research output: Contribution to journal › Article › peer-review

  • Proteolysis 100%
  • Peptides 40%
  • Proteins 39%
  • Micrococcal Nuclease 30%
  • Serine Proteases 23%