Obstetrics & Gynecology - Green Center

Research output

Research output per year 2002 2006 2007 2011 2013 2016 2017 2018 2023

• 55 Article
• 5 Review article
• 4 Comment/debate
• 3 Chapter
• 1 More
  • 1 Short survey

Research output per year

Research output per year

Search results

• Article

  A grid-enabled web service for low-resolution crystal structure refinement

  Odonovan, D. J., Stokes-Rees, I., Nam, Y., Blacklow, S. C., Schröder, G. F., Brunger, A. T. & Sliz, P., Mar 2012, In: Acta Crystallographica Section D: Biological Crystallography. 68, 3, p. 261-267 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Running 100%
  • Datasets 75%
  • X-Rays 73%
  15 Scopus citations

• A mechanism-based inactivator for histone demethylase LSD1

  Culhane, J. C., Szewczuk, L. M., Liu, X., Da, G., Marmorstein, R. & Cole, P. A., Apr 12 2006, In: Journal of the American Chemical Society. 128, 14, p. 4536-4537 2 p.

  Research output: Contribution to journal › Article › peer-review

  • Oxidoreductases 100%
  • Histone Demethylases 96%
  • Peptides 86%
  • Histone 70%
  • propargylamine 62%
  131 Scopus citations

• An Evolutionarily Conserved Structural Platform for PRC2 Inhibition by a Class of Ezh2 Inhibitors

  Bratkowski, M., Yang, X. & Liu, X., Dec 1 2018, In: Scientific reports. 8, 1, 9092.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • GSK126 100%
  • Polycomb Repressive Complex 2 94%
  • GSK343 21%
  • Fungi 18%
  • Chaetomium 17%
  25 Scopus citations

• Architecture of an RNA polymerase II transcription pre-initiation complex

  Murakami, K., Elmlund, H., Kalisman, N., Bushnell, D. A., Adams, C. M., Azubel, M., Elmlund, D., Levi-Kalisman, Y., Liu, X., Gibbons, B. J., Levitt, M. & Kornberg, R. D., 2013, In: Science. 342, 6159, 1238724.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • General Transcription Factors 100%
  • RNA Polymerase II 78%
  • DNA Polymerase II 53%
  • Mass Spectrometry 30%
  • Electron Microscopy 28%
  136 Scopus citations

• A role for the two-helix finger of the SecA ATPase in protein translocation

  Erlandson, K. J., Miller, S. B. M., Nam, Y., Osborne, A. R., Zimmer, J. & Rapoport, T. A., Oct 16 2008, In: Nature. 455, 7215, p. 984-987 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Protein Transport 100%
  • Adenosine Triphosphatases 90%
  • Fingers 82%
  • Peptides 57%
  • Tyrosine 55%
  107 Scopus citations

• Astemizole arrests the proliferation of cancer cells by disrupting the EZH2-EED interaction of polycomb repressive complex 2

  Kong, X., Chen, L., Jiao, L., Jiang, X., Lian, F., Lu, J., Zhu, K., Du, D., Liu, J., Ding, H., Zhang, N., Shen, J., Zheng, M., Chen, K., Liu, X., Jiang, H. & Luo, C., Nov 26 2014, In: Journal of Medicinal Chemistry. 57, 22, p. 9512-9521 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Astemizole 100%
  • Polycomb Repressive Complex 2 86%
  • Cell Proliferation 37%
  • H3K27Me3 36%
  • Histone 20%
  87 Scopus citations

• Catalytic mechanism of histone acetyltransferase p300: From the proton transfer to acetylation reaction

  Zhang, X., Ouyang, S., Kong, X., Liang, Z., Lu, J., Zhu, K., Zhao, D., Zheng, M., Jiang, H., Liu, X., Marmorstein, R. & Luo, C., Feb 27 2014, In: Journal of Physical Chemistry B. 118, 8, p. 2009-2019 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Proton transfer 100%
  • Acetylation 94%
  • acetylation 94%
  • Molecular dynamics 61%
  • Histone 59%
  28 Scopus citations

• Conformational locking upon cooperative assembly of notch transcription complexes

  Choi, S. H., Wales, T. E., Nam, Y., O'Donovan, D. J., Sliz, P., Engen, J. R. & Blacklow, S. C., Feb 8 2012, In: Structure. 20, 2, p. 340-349 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Ankyrins 100%
  • Ankyrin Repeat 67%
  • Kinetics 34%
  • DNA Probes 28%
  • Dimerization 26%
  52 Scopus citations

• Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2

  Long, Y., Bolanos, B., Gong, L., Liu, W., Goodrich, K. J., Yang, X., Chen, S., Gooding, A. R., Maegley, K. A., Gajiwala, K. S., Brooun, A., Cech, T. R. & Liu, X., Nov 29 2017, In: eLife. 6, e31558.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Polycomb Repressive Complex 2 100%
  • Histone 69%
  • Lysine 61%
  • Deuterium(.) 58%
  • Mutation 55%
  68 Scopus citations

• Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription

  Nam, Y., Sliz, P., Pear, W. S., Aster, J. C. & Blacklow, S. C., Feb 13 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 7, p. 2103-2108 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Genes 100%
  • Notch Receptors 86%
  • Drosophila 57%
  • Binding Sites 47%
  • Transcription Factors 46%
  125 Scopus citations

• Data publication with the structural biology data grid supports live analysis

  Meyer, P. A., Socias, S., Key, J., Ransey, E., Tjon, E. C., Buschiazzo, A., Lei, M., Botka, C., Withrow, J., Neau, D., Rajashankar, K., Anderson, K. S., Baxter, R. H., Blacklow, S. C., Boggon, T. J., Bonvin, A. M. J. J., Borek, D., Brett, T. J., Caflisch, A., Chang, C. I., & 50 othersChazin, W. J., Corbett, K. D., Cosgrove, M. S., Crosson, S., Dhe-Paganon, S., Di Cera, E., Drennan, C. L., Eck, M. J., Eichman, B. F., Fan, Q. R., Ferré-D'Amaré, A. R., Fromme, J. C., Garcia, K. C., Gaudet, R., Gong, P., Harrison, S. C., Heldwein, E. E., Jia, Z., Keenan, R. J., Kruse, A. C., Kvansakul, M., McLellan, J. S., Modis, Y., Nam, Y., Otwinowski, Z., Pai, E. F., Pereira, P. J. B., Petosa, C., Raman, C. S., Rapoport, T. A., Roll-Mecak, A., Rosen, M. K., Rudenko, G., Schlessinger, J., Schwartz, T. U., Shamoo, Y., Sondermann, H., Tao, Y. J., Tolia, N. H., Tsodikov, O. V., Westover, K. D., Wu, H., Foster, I., Fraser, J. S., Maia, F. R. N. C., Gonen, T., Kirchhausen, T., Diederichs, K., Crosas, M. & Sliz, P., Mar 7 2016, In: Nature communications. 7, 10882.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • biology 100%
  • Publications 78%
  • grids 76%
  • Datasets 74%
  • biomedical data 60%
  97 Scopus citations

• Developing EZH2-targeted therapy for lung cancer

  Frankel, A. E., Liu, X. & Minna, J. D., Sep 2016, In: Cancer discovery. 6, 9, p. 949-952 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adenocarcinoma of Lung 100%
  • Drug Discovery 96%
  • Epigenomics 81%
  • Lung Neoplasms 74%
  • In Vitro Techniques 40%
  24 Scopus citations

• Dynamic change of transcription pausing through modulating NELF protein stability regulates granulocytic differentiation

  Liu, X., Gogate, A. A., Tastemel, M., Malladi, V. S., Yao, H., Nguyen, K., Huang, L. J. S. & Bai, X., Aug 8 2017, In: Blood Advances. 1, 18, p. 1358-1367 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • negative elongation factor 100%
  • Protein Stability 64%
  • Granulocytes 6%
  • Proteins 5%
  • Stem Cells 5%
  8 Scopus citations

• Formation and fate of a complete 31-protein RNA polymerase II transcription preinitiation complex

  Murakami, K., Calero, G., Brown, C. R., Liu, X., Davis, R. E., Boeger, H. & Kornberg, R. D., Mar 1 2013, In: Journal of Biological Chemistry. 288, 9, p. 6325-6332 8 p.

  Research output: Contribution to journal › Article › peer-review

  • RNA Polymerase II 100%
  • General Transcription Factors 63%
  • Psoralen 60%
  • Ficusin 60%
  • TATA Box 55%
  25 Scopus citations

• Functional Interplay between Histone H2B ADP-Ribosylation and Phosphorylation Controls Adipogenesis

  Huang, D., Camacho, C. V., Setlem, R., Ryu, K. W., Parameswaran, B., Gupta, R. K. & Kraus, W. L., Sep 17 2020, In: Molecular cell. 79, 6, p. 934-949.e14

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • ADP-Ribosylation 100%
  • Adipogenesis 87%
  • Histones 68%
  • Phosphorylation 50%
  • NAD+ synthase 35%
  37 Scopus citations

• Generation and Characterization of Recombinant Antibody-like ADP-Ribose Binding Proteins

  Gibson, B. A., Conrad, L. B., Huang, D. & Kraus, W. L., Dec 5 2017, In: Biochemistry. 56, 48, p. 6305-6316 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Adenosine Diphosphate Ribose 100%
  • Carrier Proteins 58%
  • Antibodies 38%
  • Protein 28%
  • ADP-Ribosylation 23%
  66 Scopus citations

• Genetic suppressor screens in haploids

  Bai, X., Yang, Z., Jiang, H., Lin, S. & Zon, L. I., 2011, In: Methods in Cell Biology. 104, p. 129-136 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Haploidy 100%
  • Zebrafish 80%
  • Vertebrates 23%
  • Phenotype 15%
  • Erythropoiesis 15%
  2 Scopus citations

• Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of NOTCH signaling

  Weng, A. P., Nam, Y., Wolfe, M. S., Pear, W. S., Griffin, J. D., Blacklow, S. C. & Aster, J. C., Jan 2003, In: Molecular and cellular biology. 23, 2, p. 655-664 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Presenilins 43%
  • Growth 38%
  • Notch Receptors 21%
  • Transformed Cell Line 19%
  333 Scopus citations

• Heme enables proper positioning of Drosha and DGCR8 on primary microRNAs

  Partin, A. C., Ngo, T. D., Herrell, E., Jeong, B. C., Hon, G. & Nam, Y., Dec 1 2017, In: Nature communications. 8, 1, 1737.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • MicroRNA 100%
  • microprocessors 98%
  • Heme 90%
  • positioning 80%
  • MicroRNAs 68%
  45 Scopus citations

• HP1BP3, a Chromatin Retention Factor for Co-transcriptional MicroRNA Processing

  Liu, H., Liang, C., Kollipara, R. K., Matsui, M., Ke, X., Jeong, B. C., Wang, Z., Yoo, K. S., Yadav, G. P., Kinch, L. N., Grishin, N. V., Nam, Y., Corey, D. R., Kittler, R. & Liu, Q., Aug 4 2016, In: Molecular cell. 63, 3, p. 420-432 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Chromatin 100%
  • MicroRNAs 95%
  • Microcomputers 24%
  • Chromatin Immunoprecipitation 11%
  • Histones 9%
  26 Scopus citations

• Identification of a conserved negative regulatory sequence that influences the leukemogenic activity of NOTCH1

  Chiang, M. Y., Xu, M. L., Histen, G., Shestova, O., Roy, M., Nam, Y., Blacklow, S. C., Sacks, D. B., Pear, W. S. & Aster, J. C., Aug 2006, In: Molecular and cellular biology. 26, 16, p. 6261-6271 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Alleles 36%
  • Conserved Sequence 30%
  • Sequence Deletion 28%
  • DNA-Binding Proteins 28%
  80 Scopus citations

• Identification of PARP-7 substrates reveals a role for marylation in microtubule control in Ovarian cancer cells

  Palavalli Parsons, L. H., Challa, S., Gibson, B. A., Nandu, T., Stokes, M. S., Huang, D., Lea, J. S. & Lee Kraus, W., Jan 2021, In: eLife. 10, p. 1-61 61 p., e60481.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • ADP-Ribosylation 100%
  • Microtubules 70%
  • Ovarian Neoplasms 66%
  • Biological Role 30%
  • Protein 30%
  30 Scopus citations

• Initiation complex structure and promoter proofreading

  Liu, X., Bushnell, D. A., Silva, D. A., Huang, X. & Kornberg, R. D., Jul 29 2011, In: Science. 333, 6042, p. 633-637 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • RNA 100%
  • Nucleotides 58%
  • RNA Polymerase II 27%
  • X-Rays 18%
  • DNA 13%
  49 Scopus citations

• Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers

  Huang, F., Ni, M., Chalishazar, M. D., Huffman, K. E., Kim, J., Cai, L., Shi, X., Cai, F., Zacharias, L. G., Ireland, A. S., Li, K., Gu, W., Kaushik, A. K., Liu, X., Gazdar, A. F., Oliver, T. G., Minna, J. D., Hu, Z. & DeBerardinis, R. J., Sep 4 2018, In: Cell Metabolism. 28, 3, p. 369-382.e5

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Inosine Monophosphate 100%
  • Small Cell Lung Carcinoma 83%
  • Oxidoreductases 68%
  • Guanosine 46%
  • Nucleotides 22%
  116 Scopus citations

• LIN28 Zinc Knuckle Domain Is Required and Sufficient to Induce let-7 Oligouridylation

  Wang, L., Nam, Y., Lee, A. K., Yu, C., Roth, K., Chen, C., Ransey, E. M. & Sliz, P., Mar 14 2017, In: Cell Reports. 18, 11, p. 2664-2675 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Zinc 100%
  • MicroRNA 63%
  • UTP-RNA uridylyltransferase 54%
  • MicroRNAs 43%
  • RNA-Binding Proteins 30%
  47 Scopus citations

• Molecular Basis for Bre5 Cofactor Recognition by the Ubp3 Deubiquitylating Enzyme

  Li, K., Ossareh-Nazari, B., Liu, X., Dargemont, C. & Marmorstein, R., Sep 7 2007, In: Journal of Molecular Biology. 372, 1, p. 194-204 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Enzymes 100%
  • Hydrogen Bonding 73%
  • Protein Transport 67%
  • Proteins 67%
  • Mutagenesis 60%
  17 Scopus citations

• Molecular basis for interaction of let-7 MicroRNAs with Lin28

  Nam, Y., Chen, C., Gregory, R. I., Chou, J. J. & Sliz, P., Nov 23 2011, In: Cell. 147, 5, p. 1080-1091 12 p.

  Research output: Contribution to journal › Article › peer-review

  • MicroRNA 100%
  • MicroRNAs 68%
  • RNA 56%
  • Small Untranslated RNA 49%
  • Psychology Recognition 35%
  299 Scopus citations

• Multiple roles for acetylation in the interaction of p300 HAT with ATF-2

  Karanam, B., Wang, L., Wang, D., Liu, X., Marmorstein, R., Cotter, R. & Cole, P. A., Jul 17 2007, In: Biochemistry. 46, 28, p. 8207-8216 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Acetylation 100%
  • Lysine 46%
  • Histone 40%
  • Histones 29%
  • p300-CBP Transcription Factors 26%
  35 Scopus citations

• Notch ankyrin repeat domain variation influences leukemogenesis and Myc transactivation

  Aster, J. C., Bodnar, N., Xu, L., Karnell, F., Milholland, J. M., Maillard, I., Histen, G., Nam, Y., Blacklow, S. C. & Pear, W. S., Oct 13 2011, In: PloS one. 6, 10, e25645.

  Research output: Contribution to journal › Article › peer-review

  • Ankyrin Repeat 100%
  • ankyrins 99%
  • transcriptional activation 77%
  • lymphocytic leukemia 68%
  • T-lymphocytes 63%
  8 Scopus citations

• Oncohistone Mutations Occur at Functional Sites of Regulatory ADP-Ribosylation

  Huang, D., Camacho, C. V., Martire, S., Nagari, A., Setlem, R., Gong, X., Edwards, A. D., Chiu, S. P., Banaszynski, L. A. & Lee Kraus, W., Jul 1 2022, In: Cancer research. 82, 13, p. 2361-2377 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • ADP-Ribosylation 100%
  • Histones 68%
  • Mutation 40%
  • Growth 26%
  • Neoplasms 20%
  4 Scopus citations

• Polycomb repressive complex 2 in an autoinhibited state

  Bratkowski, M., Yang, X. & Liu, X., Aug 11 2017, In: Journal of Biological Chemistry. 292, 32, p. 13323-13332 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • H3K27Me3 100%
  • Polycomb Repressive Complex 2 80%
  • Enzyme Kinetics 63%
  • Histone 56%
  • Lysine 49%
  13 Scopus citations

• Regional control of chromatin organization by noncoding roX RNAs and the NURF remodeling complex in Drosophila melanogaster

  Bai, X., Larschan, E., Kwon, S. Y., Badenhorst, P. & Kuroda, M. I., Jul 2007, In: Genetics. 176, 3, p. 1491-1499 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Untranslated RNA 100%
  • Drosophila melanogaster 96%
  • Chromatin 78%
  • X Chromosome 71%
  • RNA 61%
  33 Scopus citations

• RNA polymerase II pausing modulates hematopoietic stem cell emergence in zebrafish

  Yang, Q., Liu, X., Zhou, T., Cook, J., Nguyen, K. & Bai, X., Sep 29 2016, In: Blood. 128, 13, p. 1701-1710 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • RNA Polymerase II 100%
  • Effector 93%
  • Zebrafish 87%
  • Hematopoietic Stem Cells 85%
  • Reduction 38%
  22 Scopus citations

• Sequence-specific targeting of Drosophila roX genes by the MSL dosage compensation complex

  Park, Y., Mengus, G., Bai, X., Kageyama, Y., Meller, V. H., Becker, P. B. & Kuroda, M. I., Apr 1 2003, In: Molecular cell. 11, 4, p. 977-986 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Genetic Dosage Compensation 100%
  • Drosophila 49%
  • RNA 36%
  • X Chromosome 23%
  • Binding Sites 16%
  61 Scopus citations

• Sequence-specific targeting of MSL complex regulates transcription of the roX RNA genes

  Bai, X., Alekseyenko, A. A. & Kuroda, M. I., Jul 21 2004, In: EMBO Journal. 23, 14, p. 2853-2861 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Lethal 100%
  • RNA 58%
  • Spreading 53%
  • Genes 33%
  • Untranslated RNA 13%
  43 Scopus citations

• Small-Molecule Inhibitors Disrupt let-7 Oligouridylation and Release the Selective Blockade of let-7 Processing by LIN28

  Wang, L., Rowe, R. G., Jaimes, A., Yu, C., Nam, Y., Pearson, D. S., Zhang, J., Xie, X., Marion, W., Heffron, G. J., Daley, G. Q. & Sliz, P., Jun 5 2018, In: Cell Reports. 23, 10, p. 3091-3101 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cold-Shock Response 100%
  • MicroRNA 92%
  • Zinc 72%
  • N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine 63%
  • MicroRNAs 63%
  73 Scopus citations

• Specific Binding of snoRNAs to PARP-1 Promotes NAD⁺-Dependent Catalytic Activation

  Huang, D., Kim, D. S. & Kraus, W. L., Apr 28 2020, In: Biochemistry. 59, 16, p. 1559-1564 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Small Nucleolar RNA 100%
  • Poly (ADP-Ribose) Polymerase-1 95%
  • Poly(ADPribose) 94%
  • NAD 71%
  • RNA 27%
  17 Scopus citations

• Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases

  Wang, P., Doxtader, K. A. & Nam, Y., Jul 21 2016, In: Molecular cell. 63, 2, p. 306-317 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Methyltransferases 100%
  • N(6)-methyladenosine 35%
  • S-Adenosylhomocysteine 34%
  • S-Adenosylmethionine 29%
  • Adenosine 22%
  776 Scopus citations

• Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes

  Nam, Y., Sliz, P., Song, L., Aster, J. C. & Blacklow, S. C., Mar 10 2006, In: Cell. 124, 5, p. 973-983 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Transcriptional Activation 100%
  • Polypeptide 90%
  • Ankyrins 77%
  • Notch Receptors 76%
  • Peptides 70%
  361 Scopus citations

• Structural Basis for Regulation of METTL16, an S-Adenosylmethionine Homeostasis Factor

  Doxtader, K. A., Wang, P., Scarborough, A. M., Seo, D., Conrad, N. K. & Nam, Y., Sep 20 2018, In: Molecular cell. 71, 6, p. 1001-1011.e4

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • S-Adenosylmethionine 100%
  • Homeostasis 55%
  • N(6)-methyladenosine 40%
  • RNA 35%
  • Methyltransferases 28%
  137 Scopus citations

• Structural basis of histone H3K27 trimethylation by an active polycomb repressive complex 2

  Jiao, L. & Liu, X., Oct 16 2015, In: Science. 350, 6258, aac4383.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Polycomb Repressive Complex 2 100%
  • Histones 61%
  • Chaetomium 37%
  • PR-SET Domains 33%
  • Peptides 27%
  281 Scopus citations

• Structural dissection of an interaction between transcription initiation and termination factors implicated in promoter-terminator cross-talk

  Bratkowski, M., Unarta, I. C., Zhu, L., Shubbar, M., Huang, X. & Liu, X., Feb 2 2018, In: Journal of Biological Chemistry. 293, 5, p. 1651-1665 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Transcription Factor TFIIB 100%
  • Peptide Initiation Factors 81%
  • Dissection 54%
  • Transcription Factors 47%
  • Plastic Property 36%
  11 Scopus citations

• Structural requirements for assembly of the CSL·intracellular Notch1·Mastermind-like 1 transcriptional activation complex

  Nam, Y., Weng, A. P., Aster, J. C. & Blacklow, S. C., Jun 6 2003, In: Journal of Biological Chemistry. 278, 23, p. 21232-21239 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Transcriptional Activation 100%
  • DNA 61%
  • Polypeptide 45%
  • Protein 45%
  • Circular Dichroism 44%
  173 Scopus citations

• Structure of a complex of the ATPase SecA and the protein-translocation channel

  Zimmer, J., Nam, Y. & Rapoport, T. A., Oct 16 2008, In: Nature. 455, 7215, p. 936-943 8 p.

  Research output: Contribution to journal › Article › peer-review

  • SecA Proteins 100%
  • Protein Transport 61%
  • Adenosine Triphosphatases 56%
  • Thermotoga maritima 46%
  • Peptides 35%
  361 Scopus citations

• Structure of an RNA polymerase II-TFIIB complex and the transcription initiation mechanism

  Liu, X., Bushnell, D. A., Wang, D., Calero, G. & Kornbergt, R. D., 2010, In: Science. 327, 5962, p. 206-209 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Transcription Factor TFIIB 100%
  • RNA Polymerase II 73%
  • General Transcription Factors 62%
  • Fingers 38%
  • X-Rays 16%
  166 Scopus citations

• Structure of human O-GlcNAc transferase and its complex with a peptide substrate

  Lazarus, M. B., Nam, Y., Jiang, J., Sliz, P. & Walker, S., Jan 27 2011, In: Nature. 469, 7331, p. 564-569 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • O-GlcNAc transferase 100%
  • Uridine Diphosphate N-Acetylglucosamine 99%
  • Uridine Diphosphate 79%
  • UDP-N-acetylglucosamine-peptide beta-N-acetylglucosaminyltransferase 54%
  • Protamine Kinase 51%
  354 Scopus citations

• Structure of the human Papillomavirus E7 oncoprotein and its mechanism for inactivation of the retinoblastoma tumor suppressor

  Liu, X., Clements, A., Zhao, K. & Marmorstein, R., Jan 6 2006, In: Journal of Biological Chemistry. 281, 1, p. 578-586 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Retinoblastoma 100%
  • Oncogene Proteins 94%
  • Tumor Suppressor Protein 66%
  • Chemical Transformation 53%
  • E2F Transcription Factors 49%
  188 Scopus citations

• Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressor

  Liu, X. & Marmorstein, R., Nov 1 2007, In: Genes and Development. 21, 21, p. 2711-2716 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Virus Inactivation 100%
  • Retinoblastoma Protein 89%
  • Oncogene Proteins 78%
  • Adenoviridae 68%
  • E2F Transcription Factors 51%
  75 Scopus citations

• Targeting dosage compensation to the X chromosome of Drosophila males

  Oh, H., Bai, X., Park, Y., Bone, J. R. & Kuroda, M. I., 2004, In: Cold Spring Harbor symposia on quantitative biology. 69, p. 81-88 8 p.

  Research output: Contribution to journal › Article › peer-review
  9 Scopus citations

• Tfb6, a previously unidentified subunit of the general transcription factor TFIIH, facilitates dissociation of Ssl2 helicase after transcription initiation

  Murakami, K., Gibbons, B. J., Davis, R. E., Nagai, S., Liu, X., Robinson, P. J. J., Wu, T., Kaplan, C. D. & Kornberg, R. D., Mar 27 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 13, p. 4816-4821 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Transcription Factor TFIIH 100%
  • General Transcription Factors 88%
  • DNA Helicases 83%
  • Factor V 76%
  • Cell Nucleus Active Transport 70%
  20 Scopus citations