Research output per year
Research output per year
- 1 - 50 out of 786 results
Search results
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2024
AXL/WRNIP1 Mediates Replication Stress Response and Promotes Therapy Resistance and Metachronous Metastasis in HER2+ Breast Cancer
Marquez-Palencia, M., Herrera, L. R., Parida, P. K., Ghosh, S., Kim, K., Das, N. M., Gonzalez-Ericsson, P. I., Sanders, M. E., Mobley, B. C., Diegeler, S., Aguilera, T. A., Peng, Y., Lewis, C. M., Arteaga, C. L., Hanker, A. B., Whitehurst, A. W., Lorens, J. B., Brekken, R. A., Davis, A. J. & Malladi, S., Mar 1 2024, In: Cancer research. 84, 5, p. 675-687 13 p.Research output: Contribution to journal › Article › peer-review
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2023
A longitudinal study of polygenic score and cognitive function decline considering baseline cognitive function, lifestyle behaviors, and diabetes among middle-aged and older US adults
Liu, T., Li, C., Zhang, R., Millender, E. F., Miao, H., Ormsbee, M., Guo, J., Westbrook, A., Pan, Y., Wang, J. & Kelly, T. N., Dec 2023, In: Alzheimer's Research and Therapy. 15, 1, 196.Research output: Contribution to journal › Article › peer-review
Open Access -
An injectable subcutaneous colon-specific immune niche for the treatment of ulcerative colitis
Au, K. M., Wilson, J. E., Ting, J. P. Y. & Wang, A. Z., 2023, (Accepted/In press) In: Nature Biomedical Engineering.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
A single photodynamic priming protocol augments delivery of ⍺-PD-L1 mAbs and induces immunogenic cell death in head and neck tumors*
Bhandari, C., Moffat, A., Fakhry, J., Malkoochi, A., Nguyen, A., Trinh, B., Hoyt, K., Story, M. D., Hasan, T. & Obaid, G., 2023, (Accepted/In press) In: Photochemistry and Photobiology.Research output: Contribution to journal › Article › peer-review
Open Access -
ATM phosphorylates the FATC domain of DNA-PKcsat threonine 4102 to promote non-homologous end joining
Lu, H., Zhang, Q., Laverty, D. J., Puncheon, A. C., Augustine, M. M., Williams, G. J., Nagel, Z. D., Chen, B. P. C. & Davis, A. J., Jul 21 2023, In: Nucleic acids research. 51, 13, p. 6770-6783 14 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Biomimetic Human Lung Alveolar Interstitium Chip with Extended Longevity
Man, K., Liu, J., Liang, C., Corona, C., Story, M. D., Meckes, B. & Yang, Y., Aug 2 2023, In: ACS Applied Materials and Interfaces. 15, 30, p. 36888-36898 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
DNAJA2 deficiency activates cGAS-STING pathway via the induction of aberrant mitosis and chromosome instability
Huang, Y., Lu, C., Wang, H., Gu, L., Fu, Y. X. & Li, G. M., Dec 2023, In: Nature communications. 14, 1, 5246.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
DNA-PKcs and ATM modulate mitochondrial ADP-ATP exchange as an oxidative stress checkpoint mechanism
Chen, W. M., Chiang, J. C., Shang, Z., Palchik, G., Newman, C., Zhang, Y., Davis, A. J., Lee, H. & Chen, B. P. C., Mar 15 2023, In: EMBO Journal. 42, 6, e112094.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining
Head, P. S. E., Kapoor-Vazirani, P., Nagaraju, G. P., Zhang, H., Rath, S. K., Luong, N. C., Haji-Seyed-Javadi, R., Sesay, F., Wang, S. Y., Duong, D. M., Daddacha, W., Minten, E. V., Song, B., Danelia, D., Liu, X., Li, S., Ortlund, E. A., Seyfried, N. T., Smalley, D. M., Wang, Y., & 5 others, Aug 25 2023, In: Nucleic acids research. 51, 15, p. 7972-7987 16 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Dynamic ultrasound molecular-targeted imaging of senescence in evaluation of lapatinib resistance in HER2-positive breast cancer
Chen, X., Li, Y., Zhou, Z., Zhang, Y., Chang, L., Gao, X., Li, Q., Luo, H., Westover, K. D., Zhu, J. & Wei, X., Oct 2023, In: Cancer Medicine. 12, 19, p. 19904-19920 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
GLUT3 promotes macrophage signaling and function via RAS-mediated endocytosis in atopic dermatitis and wound healing
Yu, D. M., Zhao, J., Lee, E. E., Kim, D., Mahapatra, R., Rose, E. K., Zhou, Z., Hosler, C., El Kurdi, A., Choe, J. Y., Abel, E. D., Hoxhaj, G., Westover, K. D., Cho, R. J., Cheng, J. B. & Wang, R. C., Nov 1 2023, In: Journal of Clinical Investigation. 133, 21, e170706.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Heat shock protein DNAJA2 regulates transcription-coupled repair by triggering CSB degradation via chaperone-mediated autophagy
Huang, Y., Gu, L. & Li, G. M., Dec 2023, In: Cell Discovery. 9, 1, 107.Research output: Contribution to journal › Article › peer-review
Open Access -
Integrated Small Animal PET/CT/RT with Onboard PET/CT Image Guidance for Preclinical Radiation Oncology Research
Cheng, X., Yang, D., Saha, D., Sun, X. & Shao, Y., Apr 2023, In: Tomography. 9, 2, p. 567-578 12 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
miR-551a and miR-551b-3p target GLIPR2 and promote tumor growth in high-risk head and neck cancer by modulating autophagy
Karanam, N. K., Ding, L., Vo, D. T., Giri, U., Yordy, J. S. & Story, M. D., Jul 2023, In: Advances in Cancer Biology - Metastasis. 7, 100085.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Persistent changes in expression of genes involved in inflammation and fibrosis in the lungs of rats exposed to airborne lunar dust
Zhang, Y., Story, M., Yeshitla, S., Wang, X., Scully, R. R., Theriot, C., Wu, H., Ryder, V. E. & Lam, C. W., 2023, In: Inhalation Toxicology. 35, 5-6, p. 139-156 18 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
The cancer testes antigen, HORMAD1, limits genomic instability in cancer cells by protecting stalled replication forks
Herrera, L. R., Johnson, R. A., McGlynn, K., Gibbs, Z. A., Davis, A. J. & Whitehurst, A. W., Nov 2023, In: Journal of Biological Chemistry. 299, 11, 105348.Research output: Contribution to journal › Article › peer-review
Open Access -
Towards precision radiation oncology: endocrine therapy response as a biomarker for personalization of breast radiotherapy
Udden, S. M. N., Baek, G. H., Pandey, K., Vidal, C., Liu, Y., Rahimi, A. S., Kim, D. N., Nwachukwu, C. R., Mani, R. S. & Alluri, P. G., Dec 2023, In: npj Precision Oncology. 7, 1, 11.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
CXCR4 knockdown enhances sensitivity of paclitaxel via the PI3K/Akt/mTOR pathway in ovarian carcinoma
Zi, D., Li, Q., Xu, C. X., Zhou, Z. W., Song, G. B., Hu, C. B., Wen, F., Yang, H. L., Nie, L., Zhao, X., Tan, J., Zhou, S. F. & He, Z. X., 2022, In: Aging. 14, 11, p. 4673-4698 26 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Dimensionality-Dependent Mechanical Stretch Regulation of Cell Behavior
Man, K., Liu, J., Phan, K. M., Wang, K., Lee, J. Y., Sun, X., Story, M., Saha, D., Liao, J., Sadat, H. & Yang, Y., Apr 20 2022, In: ACS Applied Materials and Interfaces. 14, 15, p. 17081-17092 12 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
DNA-PKcs-dependent phosphorylation of RECQL4 promotes NHEJ by stabilizing the NHEJ machinery at DNA double-strand breaks
Lu, H., Guan, J., Wang, S. Y., Li, G. M., Bohr, V. A. & Davis, A. J., Jun 10 2022, In: Nucleic acids research. 50, 10, p. 5635-5651 17 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Evaluation of the Response of HNSCC Cell Lines to γ-Rays and 12C Ions: Can Radioresistant Tumors Be Identified and Selected for 12C Ion Radiotherapy?
Ding, L., Sishc, B. J., Polsdofer, E., Yordy, J. S., Facoetti, A., Ciocca, M., Saha, D., Pompos, A., Davis, A. J. & Story, M. D., Feb 25 2022, In: Frontiers in Oncology. 12, 812961.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Immune Checkpoint Ligand Bioengineered Schwann Cells as Antigen-Specific Therapy for Experimental Autoimmune Encephalomyelitis
Au, K. M., Tisch, R. & Wang, A. Z., Feb 3 2022, In: Advanced Materials. 34, 5, 2107392.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Interplay between H3K36me3, methyltransferase SETD2, and mismatch recognition protein MutSα facilitates processing of oxidative DNA damage in human cells
Guo, S., Fang, J., Xu, W., Ortega, J., Liu, C. Y., Gu, L., Chang, Z. & Li, G. M., Jul 2022, In: Journal of Biological Chemistry. 298, 7, 102102.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Lung Cancer Targeted Chemoradiotherapy via Dual-Stimuli Responsive Biodegradable Core-Shell Nanoparticles
Iyer, R., Ramachandramoorthy, H., Nguyen, T., Xu, C., Fu, H., Kotadia, T., Chen, B., Hong, Y., Saha, D. & Nguyen, K. T., Aug 2022, In: Pharmaceutics. 14, 8, 1525.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Lysophosphatidic Acid Receptor 3 Promotes Mitochondrial Homeostasis against Oxidative Stress: Potential Therapeutic Approaches for Hutchinson–Gilford Progeria Syndrome
Chiang, J. C., Chen, W. M., Newman, C., Chen, B. P. C. & Lee, H., Feb 2022, In: Antioxidants. 11, 2, 351.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Mitotic phosphorylation of tumor suppressor DAB2IP maintains spindle assembly checkpoint and chromosomal stability through activating PLK1-Mps1 signal pathway and stabilizing mitotic checkpoint complex
Yu, L., Lang, Y., Hsu, C. C., Chen, W. M., Chiang, J. C., Hsieh, J. T., Story, M. D., Shang, Z. F., Chen, B. P. C. & Saha, D., Jan 21 2022, In: Oncogene. 41, 4, p. 489-501 13 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
NBS1-CtIP-mediated DNA end resection suppresses cGAS binding to micronuclei
Abdisalaam, S., Mukherjee, S., Bhattacharya, S., Kumari, S., Sinha, D., Ortega, J., Li, G. M., Sadek, H. A., Krishnan, S. & Asaithamby, A., Mar 21 2022, In: Nucleic acids research. 50, 5, p. 2681-2699 19 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Orthologs of human circulating miRNAs associated with hepatocellular carcinoma are elevated in mouse plasma months before tumour detection
Ding, L. H., Fallgren, C. M., Yu, Y., McCarthy, M., Edmondson, E. F., Ullrich, R. L., Weil, M. M. & Story, M. D., Dec 2022, In: Scientific reports. 12, 1, 10927.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
PD-L1P146R is prognostic and a negative predictor of response to immunotherapy in gastric cancer
Li, Q., Zhou, Z. W., Lu, J., Luo, H., Wang, S. N., Peng, Y., Deng, M. S., Song, G. B., Wang, J. M., Wei, X., Wang, D., Westover, K. D. & Xu, C. X., Feb 2 2022, In: Molecular Therapy. 30, 2, p. 621-631 11 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Phase II Trial of Sipuleucel-T and Stereotactic Ablative Body Radiation for Patients with Metastatic Castrate-Resistant Prostate Cancer
Hannan, R., Dohopolski, M. J., Pop, L. M., Mannala, S., Watumull, L., Mathews, D., Gao, A., Garant, A., Arriaga, Y. E., Bowman, I., Chung, J. S., Wang, J., Ariizumi, K., Ahn, C., Timmerman, R. & Courtney, K., Jun 2022, In: Biomedicines. 10, 6, 1419.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Protein Phosphatase 2A–Dependent Mitotic hnRNPA1 Dephosphorylation and TERRA Formation Facilitate Telomere Capping
Sui, J. D., Tang, Z., Chen, B. P. C., Huang, P., Yang, M. Q., Wang, N. H., Yang, H. N., Tu, H. L., Jiang, Q. M., Zhang, J., Wang, Y. & Wu, Y. Z., Apr 2022, In: Molecular Cancer Research. 20, 4, p. 583-595 13 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Restoration of DNA repair mitigates genome instability and increases productivity of Chinese hamster ovary cells
Spahn, P. N., Zhang, X., Hu, Q., Lu, H., Hamaker, N. K., Hefzi, H., Li, S., Kuo, C. C., Huang, Y., Lee, J. C., Davis, A. J., Ly, P., Lee, K. H. & Lewis, N. E., Mar 2022, In: Biotechnology and Bioengineering. 119, 3, p. 963-982 20 p.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Targeting radioresistance and replication fork stability in prostate cancer
Li, X., Baek, G. H., Carreira, S., Yuan, W., Ma, S., Hofstad, M., Lee, S., Gao, Y., Bertan, C., de los Dolores Fenor de la Maza, M., Alluri, P. G., Burma, S., Chen, B. P. C., Raj, G. V., de Bono, J., Pommier, Y. & Mani, R. S., May 9 2022, In: JCI Insight. 7, 9, e152955.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
The mismatch recognition protein MutSα promotes nascent strand degradation at stalled replication forks
Zhang, J., Zhao, X., Liu, L., Li, H. D., Gu, L., Castrillon, D. H. & Li, G. M., Oct 4 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 40, e2201738119.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2021
Ablating putative Ku70 phosphorylation sites results in defective DNA damage repair and spontaneous induction of hepatocellular carcinoma
Saha, J., Bae, J., Wang, S. Y., Lu, H., Chappell, L. J., Gopal, P. & Davis, A. J., Sep 27 2021, In: Nucleic acids research. 49, 17, p. 9836-9850 15 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
A structural model of a Ras–Raf signalosome
Mysore, V. P., Zhou, Z. W., Ambrogio, C., Li, L., Kapp, J. N., Lu, C., Wang, Q., Tucker, M. R., Okoro, J. J., Nagy-Davidescu, G., Bai, X., Plückthun, A., Jänne, P. A., Westover, K. D., Shan, Y. & Shaw, D. E., Oct 2021, In: Nature Structural and Molecular Biology. 28, 10, p. 847-857 11 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
Avasopasem manganese synergizes with hypofractionated radiation to ablate tumors through the generation of hydrogen peroxide
Sishc, B. J., Ding, L., Nam, T. K., Heer, C. D., Rodman, S. N., Schoenfeld, J. D., Fath, M. A., Saha, D., Pulliam, C. F., Langen, B., Beardsley, R. A., Riley, D. P., Keene, J. L., Spitz, D. R. & Story, M. D., May 12 2021, In: Science translational medicine. 13, 593, eabb3768.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Blood-based biomarkers of human papillomavirus–associated cancers: A systematic review and meta-analysis
Balachandra, S., Kusin, S. B., Lee, R., Blackwell, J. M., Tiro, J. A., Cowell, L. G., Chiang, C. M., Wu, S. Y., Varma, S., Rivera, E. L., Mayo, H. G., Ding, L., Sumer, B. D., Lea, J. S., Bagrodia, A., Farkas, L. M., Wang, R., Fakhry, C., Dahlstrom, K. R., Sturgis, E. M., & 1 others, Mar 15 2021, In: Cancer. 127, 6, p. 850-864 15 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Boosted efficientnet: Detection of lymph node metastases in breast cancer using convolutional neural networks
Wang, J., Liu, Q., Xie, H., Yang, Z. & Zhou, H., Feb 2 2021, In: Cancers. 13, 4, p. 1-14 14 p., 661.Research output: Contribution to journal › Article › peer-review
Open Access64 Scopus citations -
BRCA1-BARD1 regulates transcription through modulating topoisomerase IIβ
Bunch, H., Jeong, J., Kang, K., Jo, D. S., Cong, A. T. Q., Kim, D., Kim, D., Cho, D. H., Lee, Y. M., Chen, B. P. C., Schellenberg, M. J. & Calderwood, S. K., Oct 1 2021, In: Open Biology. 11, 10, 210221.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
DNA-PKcs inhibition impairs HDAC6-mediated HSP90 chaperone function on Aurora A and enhances HDACs inhibitor-induced cell killing by increasing mitotic aberrant spindle assembly
Yu, L., Lang, Y., Guo, J., Cai, J., Shang, Z. F. & Chen, B. P. C., 2021, In: Cell Cycle. 20, 2, p. 211-224 14 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
DNA polymerase θ promotes CAG CTG repeat expansions in Huntington’s disease via insertion sequences of its catalytic domain
Chan, K. Y., Li, X., Ortega, J., Gu, L. & Li, G. M., Oct 1 2021, In: Journal of Biological Chemistry. 297, 4, 101144.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity
Lu, C., Guan, J., Lu, S., Jin, Q., Rousseau, B., Lu, T., Stephens, D., Zhang, H., Zhu, J., Yang, M., Ren, Z., Liang, Y., Liu, Z., Han, C., Liu, L., Cao, X., Zhang, A., Qiao, J., Batten, K., Chen, M., & 6 others, Jan 11 2021, In: Cancer Cell. 39, 1, p. 96-108.e6Research output: Contribution to journal › Article › peer-review
Open Access142 Scopus citations -
Elimination of Radiation-Induced Senescence in the Brain Tumor Microenvironment Attenuates Glioblastoma Recurrence
Fletcher-Sananikone, E., Kanji, S., Tomimatsu, N., Cristofaro, L. F. M. E. D., Kollipara, R. K., Saha, D., Floyd, J. R., Sung, P., Hromas, R., Burns, T. C., Kittler, R., Habib, A. A., Mukherjee, B. & Burma, S., Dec 1 2021, In: Cancer research. 81, 23, p. 5935-5947 13 p.Research output: Contribution to journal › Article › peer-review
Open Access56 Scopus citations -
Facile and direct detection of human papillomavirus (HPV) DNA in cells using loop-mediated isothermal amplification (LAMP)
Vo, D. T. & Story, M. D., Oct 2021, In: Molecular and Cellular Probes. 59, 101760.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Impaired DNA Repair Fidelity in a Breast Cancer Patient With Adverse Reactions to Radiotherapy
Alsbeih, G., Al-Harbi, N., Ismail, S. & Story, M., Jun 7 2021, In: Frontiers in Public Health. 9, 647563.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Inhibiting the redox function of APE1 suppresses cervical cancer metastasis via disengagement of ZEB1 from E-cadherin in EMT
Li, Q., Zhou, Z. W., Duan, W., Qian, C. Y., Wang, S. N., Deng, M. S., Zi, D., Wang, J. M., Mao, C. Y., Song, G., Wang, D., Westover, K. D. & Xu, C. X., Dec 2021, In: Journal of Experimental and Clinical Cancer Research. 40, 1, 220.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations -
In Vivo Bioengineering of Beta Cells with Immune Checkpoint Ligand as a Treatment for Early-Onset Type 1 Diabetes Mellitus
Au, K. M., Tisch, R. & Wang, A. Z., Dec 28 2021, In: ACS Nano. 15, 12, p. 19990-20002 13 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
LncRNA HOTAIR regulates glucose transporter Glut1 expression and glucose uptake in macrophages during inflammation
Obaid, M., Udden, S. M. N., Alluri, P. & Mandal, S. S., Dec 2021, In: Scientific reports. 11, 1, 232.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
Lysophosphatidic acid receptors 2 and 3 regulate erythropoiesis at different hematopoietic stages
Chiang, J. C., Chen, W. M., Lin, K. H., Hsia, K., Ho, Y. H., Lin, Y. C., Shen, T. L., Lu, J. H., Chen, S. K., Yao, C. L., Chen, B. P. C. & Lee, H., Jan 2021, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1866, 1, 158818.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations