Research output per year
Research output per year
- 1 - 50 out of 382 results
Search results
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2024
Associations of postprandial ghrelin, liver-expressed antimicrobial peptide 2 and leptin levels with body composition, disease progression and survival in patients with amyotrophic lateral sclerosis
Howe, S. L., Holdom, C. J., McCombe, P. A., Henderson, R. D., Zigman, J. M., Ngo, S. T. & Steyn, F. J., Jan 2024, In: European Journal of Neurology. 31, 1, e16052.Research output: Contribution to journal › Article › peer-review
Open Access -
E3 ubiquitin ligase Herc3 deficiency leads to accumulation of subretinal microglia and retinal neurodegeneration
Zegeye, Y., Aredo, B., Yuksel, S., Kirman, D. C., Kumar, A., Chen, B., Turpin, E., Shresta, S., He, Y. G., Gautron, L., Tang, M., Li, X., DiCesare, S. M., Hulleman, J. D., Xing, C., Ludwig, S., Moresco, E. M. Y., Beutler, B. A. & Ufret-Vincenty, R. L., Dec 2024, In: Scientific reports. 14, 1Research output: Contribution to journal › Article › peer-review
Open Access -
Gpr149 is involved in energy homeostasis in the male mouse
Wyler, S., Surbhi, Cao, N., Merchant, W., Bookout, A. & Gautron, L., 2024, In: PeerJ. 12, e16739.Research output: Contribution to journal › Article › peer-review
Open Access -
Leptin Reduction as a Required Component for Weight Loss
Zhao, S., Li, N., Xiong, W., Li, G., He, S., Zhang, Z., Zhu, Q., Jiang, N., Ikejiofor, C., Zhu, Y., Wang, M. Y., Han, X., Zhang, N., Solis-Herrera, C., Kusminski, C., An, Z., Elmquist, J. K. & Scherer, P. E., Feb 2024, In: Diabetes. 73, 2, p. 197-210 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Effects of thermoneutrality on food intake, body weight, and body composition in a Prader-Willi syndrome mouse model
Osborne-Lawrence, S., Lawrence, C., Metzger, N. P., Klavon, J., Baig, H. R., Richard, C., Varshney, S., Gupta, D., Singh, O., Ogden, S. B., Shankar, K., Paul, S., Butler, R. K. & Zigman, J. M., Jun 2023, In: Obesity. 31, 6, p. 1644-1654 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Endogenous renal adiponectin drives gluconeogenesis through enhancing pyruvate and fatty acid utilization
Onodera, T., Wang, M. Y., Rutkowski, J. M., Deja, S., Chen, S., Balzer, M. S., Kim, D. S., Sun, X., An, Y. A., Field, B. C., Lee, C., Matsuo, E. I., Mizerska, M., Sanjana, I., Fujiwara, N., Kusminski, C. M., Gordillo, R., Gautron, L., Marciano, D. K., Hu, M. C., & 4 others, Dec 2023, In: Nature communications. 14, 1, 6531.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Evidence of extraganglionic vagal mechanoreceptors in the mouse vagus nerve
Leon-Mercado, L., Tinajero, A. & Gautron, L., Dec 2023, In: Journal of Anatomy. 243, 6, p. 936-950 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
FGF21 counteracts alcohol intoxication by activating the noradrenergic nervous system
Choi, M., Schneeberger, M., Fan, W., Bugde, A., Gautron, L., Vale, K., Hammer, R. E., Zhang, Y., Friedman, J. M., Mangelsdorf, D. J. & Kliewer, S. A., Mar 7 2023, In: Cell Metabolism. 35, 3, p. 429-437.e5Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Forward genetic screening using fundus spot scale identifies an essential role for Lipe in murine retinal homeostasis
Yuksel, S., Aredo, B., Zegeye, Y., Zhao, C. X., Tang, M., Li, X., Hulleman, J. D., Gautron, L., Ludwig, S., Moresco, E. M. Y., Butovich, I. A., Beutler, B. A. & Ufret-Vincenty, R. L., Dec 2023, In: Communications Biology. 6, 1, 533.Research output: Contribution to journal › Article › peer-review
Open Access -
Ghrelin deletion and conditional ghrelin cell ablation increase pancreatic islet size in mice
Gupta, D., Burstein, A. W., Schwalbe, D. C., Shankar, K., Varshney, S., Singh, O., Paul, S., Ogden, S. B., Osborne-Lawrence, S., Metzger, N. P., Richard, C. P., Campbell, J. N. & Zigman, J. M., Dec 1 2023, In: Journal of Clinical Investigation. 133, 24, e16934.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Ghrelin does not impact the blunted counterregulatory response to recurrent hypoglycemia in mice
Shankar, K., Varshney, S., Gupta, D., Mani, B. K., Osborne-Lawrence, S., Metzger, N. P., Richard, C. P. & Zigman, J. M., 2023, In: Frontiers in Endocrinology. 14, 1181856.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Ghrelin-responsive mediobasal hypothalamic neurons mediate exercise-associated food intake and exercise endurance
Singh, O., Ogden, S. B., Varshney, S., Shankar, K., Gupta, D., Paul, S., Osborne-Lawrence, S., Richard, C. P., Metzger, N. P., Lawrence, C., Mercado, L. L. & Zigman, J. M., 2023, In: JCI Insight. 8, 24, e172549.Research output: Contribution to journal › Article › peer-review
Open Access -
Ghrelin signalling in AgRP neurons links metabolic state to the sensory regulation of AgRP neural activity
So, W. L., Hu, J., Jeffs, L., Dempsey, H., Lockie, S. H., Zigman, J. M., Stark, R., Reichenbach, A. & Andrews, Z. B., Dec 2023, In: Molecular Metabolism. 78, 101826.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Ghrelin's orexigenic action in the lateral hypothalamic area involves indirect recruitment of orexin neurons and arcuate nucleus activation
Barrile, F., Cassano, D., Fernandez, G., De Francesco, P. N., Reynaldo, M., Cantel, S., Fehrentz, J. A., Donato, J., Schiöth, H. B., Zigman, J. M. & Perello, M., Oct 2023, In: Psychoneuroendocrinology. 156, 106333.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Hyperleptinemia contributes to antipsychotic drug–associated obesity and metabolic disorders
Zhao, S., Lin, Q., Xiong, W., Li, L., Straub, L., Zhang, D., Zapata, R., Zhu, Q., Sun, X. N., Zhang, Z., Funcke, J. B., Li, C., Chen, S., Zhu, Y., Jiang, N., Li, G., Xu, Z., Wyler, S. C., Wang, M. Y., Bai, J., & 8 others, Nov 15 2023, In: Science translational medicine. 15, 723, eade8460.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Liver-expressed antimicrobial peptide 2 elevation contributes to age-associated cognitive decline
Tian, J., Guo, L., Wang, T., Jia, K., Swerdlow, R. H., Zigman, J. M. & Du, H., May 8 2023, In: JCI Insight. 8, 10, e166175.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Melanocortin 4 receptor signaling in Sim1 neurons permits sexual receptivity in female mice
Semple, E. A., Harberson, M. T., Xu, B., Rashleigh, R., Cartwright, T. L., Braun, J. J., Custer, A. C., Liu, C. & Hill, J. W., 2023, In: Frontiers in Endocrinology. 14, 983670.Research output: Contribution to journal › Article › peer-review
Open Access -
Peut-on affranchir la recherche biomédicale du modèle managérial ?
Translated title of the contribution :Can we save biomedical research from the managerial model? Research output: Contribution to journal › Article › peer-review
Open Access -
Sample enrichment for single-nucleus sequencing using concanavalin A-conjugated magnetic beads
Li, L., Xu, B. & Liu, C., Dec 15 2023, In: STAR Protocols. 4, 4, 102595.Research output: Contribution to journal › Article › peer-review
Open Access -
VMHdm/cSF-1 neuronal circuits regulate skeletal muscle PGC1-α via the sympathoadrenal drive
Yoshida, T., Fujitani, M., Farmer, S., Harada, A., Shi, Z., Lee, J. J., Tinajero, A., Singha, A. K. & Fujikawa, T., Nov 2023, In: Molecular Metabolism. 77, 101792.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
A closer look at alcohol-induced changes in the ghrelin system: novel insights from preclinical and clinical data
Deschaine, S. L., Farokhnia, M., Gregory-Flores, A., Zallar, L. J., You, Z. B., Sun, H., Harvey, D. M., Marchette, R. C. N., Tunstall, B. J., Mani, B. K., Moose, J. E., Lee, M. R., Gardner, E., Akhlaghi, F., Roberto, M., Hougland, J. L., Zigman, J. M., Koob, G. F., Vendruscolo, L. F. & Leggio, L., Jan 2022, In: Addiction Biology. 27, 1, e13033.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Activating Connexin43 gap junctions primes adipose tissue for therapeutic intervention
Zhu, Y., Li, N., Huang, M., Chen, X., An, Y. A., Li, J., Zhao, S., Funcke, J. B., Cao, J., He, Z., Zhu, Q., Zhang, Z., Wang, Z. V., Xu, L., Williams, K. W., Li, C., Grove, K. & Scherer, P. E., Jul 2022, In: Acta Pharmaceutica Sinica B. 12, 7, p. 3063-3072 10 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure
Katsumura, S., Siddiqui, N., Goldsmith, M. R., Cheah, J. H., Fujikawa, T., Minegishi, G., Yamagata, A., Yabuki, Y., Kobayashi, K., Shirouzu, M., Inagaki, T., Huang, T. H. M., Musi, N., Topisirovic, I., Larsson, O. & Morita, M., Apr 5 2022, In: Cell Metabolism. 34, 4, p. 564-580.e8Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Delineating a serotonin 1B receptor circuit for appetite suppression in mice
Li, L., Wyler, S. C., León-Mercado, L. A., Xu, B., Oh, Y., Swati, Chen, X., Wan, R., Arnold, A. G., Jia, L., Wang, G., Nautiyal, K., Hen, R., Sohn, J. W. & Liu, C., Aug 1 2022, In: Journal of Experimental Medicine. 219, 8, e20212307.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Growth hormone secretagogue receptor signaling in the supramammillary nucleus targets nitric oxide-producing neurons and controls recognition memory in mice
Aguggia, J. P., Cornejo, M. P., Fernandez, G., De Francesco, P. N., Mani, B. K., Cassano, D., Cabral, A., Valdivia, S., García Romero, G., Reynaldo, M., Fehrentz, J. A., Zigman, J. M. & Perello, M., May 2022, In: Psychoneuroendocrinology. 139, 105716.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Hepatic non-parenchymal S100A9-TLR4-mTORC1 axis normalizes diabetic ketogenesis
Ursino, G., Ramadori, G., Höfler, A., Odouard, S., Teixeira, P. D. S., Visentin, F., Veyrat-Durebex, C., Lucibello, G., Firnkes, R., Ricci, S., Vianna, C. R., Jia, L., Dirlewanger, M., Klee, P., Elmquist, J. K., Roth, J., Vogl, T., Schwitzgebel, V. M., Jornayvaz, F. R., Boland, A., & 1 others, Dec 2022, In: Nature communications. 13, 1, 4107.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Leptin-inhibited neurons in the lateral parabrachial nucleus do not alter food intake or glucose balance
Park, S., Williams, K. W. & Sohn, J. W., 2022, In: Animal Cells and Systems. 26, 3, p. 92-98 7 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Sustained inhibition of NPY/AgRP neuronal activity by FGF1
Hwang, E., Scarlett, J. M., Baquero, A. F., Bennett, C. M., Dong, Y., Chau, D., Brown, J. M., Mercer, A. J., Meek, T. H., Grove, K. L., Phan, B. A. N., Morton, G. J., Williams, K. W. & Schwartz, M. W., Sep 8 2022, In: JCI Insight. 7, 17, e160891.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2021
Adipocyte iron levels impinge on a fat-gut crosstalk to regulate intestinal lipid absorption and mediate protection from obesity
Zhang, Z., Funcke, J. B., Zi, Z., Zhao, S., Straub, L. G., Zhu, Y., Zhu, Q., Crewe, C., An, Y. A., Chen, S., Li, N., Wang, M. Y., Ghaben, A. L., Lee, C., Gautron, L., Engelking, L. J., Raj, P., Deng, Y., Gordillo, R., Kusminski, C. M., & 1 others, Aug 3 2021, In: Cell Metabolism. 33, 8, p. 1624-1639.e9Research output: Contribution to journal › Article › peer-review
Open Access49 Scopus citations -
Cannabinoid receptor 1 signaling in hepatocytes and stellate cells does not contribute to NAFLD
Wang, S., Zhu, Q., Liang, G., Franks, T., Boucher, M., Bence, K. K., Lu, M., Castorena, C. M., Zhao, S., Elmquist, J. K., Scherer, P. E. & Horton, J. D., Nov 15 2021, In: Journal of Clinical Investigation. 131, 22, e152242.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
CB1Rs in VMH neurons regulate glucose homeostasis but not body weight
Castorena, C. M., Caron, A., Michael, N. J., Ahmed, N. I., Arnold, A. G., Lee, J., Lee, C., Limboy, C., Tinajero, A. S., Granier, M., Wang, S., Horton, J. D., Holland, W. L., Lee, S., Liu, C., Fujikawa, T. & Elmquist, J. K., Jul 2021, In: American Journal of Physiology - Endocrinology and Metabolism. 321, 1, p. E146–E155Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Central regulation of glucose metabolism in an insulin-dependent and -independent manner
Fujikawa, T., Apr 2021, In: Journal of Neuroendocrinology. 33, 4, e12941.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Characterization of a cell bridge variant connecting the nodose and superior cervical ganglia in the mouse: Prevalence, anatomical features, and practical implications
Bookout, A. L. & Gautron, L., Jan 2021, In: Journal of Comparative Neurology. 529, 1, p. 111-128 18 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Detection of g protein-coupled receptor expression in mouse vagal afferent neurons using multiplex in situ hybridization
Bob-Manuel, J. & Gautron, L., Sep 2021, In: Journal of Visualized Experiments. 2021, 175, e62945.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Disrupting the ghrelin-growth hormone axis limits ghrelin's orexigenic but not glucoregulatory actions
Gupta, D., Patterson, A. M., Osborne-Lawrence, S., Bookout, A. L., Varshney, S., Shankar, K., Singh, O., Metzger, N. P., Richard, C. P., Wyler, S. C., Elmquist, J. K. & Zigman, J. M., Nov 2021, In: Molecular Metabolism. 53, 101258.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Genetic deletion of the ghrelin receptor (GHSR) impairs growth and blunts endocrine response to fasting in Ghsr-IRES-Cre mice
Peris-Sampedro, F., Stoltenborg, I., Le May, M. V., Zigman, J. M., Adan, R. A. H. & Dickson, S. L., Sep 2021, In: Molecular Metabolism. 51, 101223.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Ghrelin cell–expressed insulin receptors mediate meal- And obesity-induced declines in plasma ghrelin
Shankar, K., Takemi, S., Gupta, D., Varshney, S., Mani, B. K., Osborne-Lawrence, S., Metzger, N. P., Richard, C. P., Berglund, E. D. & Zigman, J. M., Sep 22 2021, In: JCI Insight. 6, 18, e146983.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Gαi/o-coupled Htr2c in the paraventricular nucleus of the hypothalamus antagonizes the anorectic effect of serotonin agents
Yoo, E. S., Li, L., Jia, L., Lord, C. C., Lee, C. E., Birnbaum, S. G., Vianna, C. R., Berglund, E. D., Cunningham, K. A., Xu, Y., Sohn, J. W. & Liu, C., Nov 16 2021, In: Cell Reports. 37, 7, 109997.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Hepatic Krüppel-like factor 16 (KLF16) targets PPARα to improve steatohepatitis and insulin resistance
Sun, N., Shen, C., Zhang, L., Wu, X., Yu, Y., Yang, X., Yang, C., Zhong, C., Gao, Z., Miao, W., Yang, Z., Gao, W., Hu, L., Williams, K., Liu, C., Chang, Y. & Gao, Y., Nov 1 2021, In: Gut. 70, 11, p. 2183-2195 13 p.Research output: Contribution to journal › Article › peer-review
Open Access54 Scopus citations -
High coexpression of the ghrelin and LEAP2 receptor GHSR with pancreatic polypeptide in mouse and human islets
Gupta, D., Dowsett, G. K. C., Mani, B. K., Shankar, K., Osborne-Lawrence, S., Metzger, N. P., Lam, B. Y. H., Yeo, G. S. H. & Zigman, J. M., Oct 1 2021, In: Endocrinology. 162, 10Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
LEAP2 deletion in mice enhances ghrelin's actions as an orexigen and growth hormone secretagogue
Shankar, K., Metzger, N. P., Singh, O., Mani, B. K., Osborne-Lawrence, S., Varshney, S., Gupta, D., Ogden, S. B., Takemi, S., Richard, C. P., Nandy, K., Liu, C. & Zigman, J. M., Nov 2021, In: Molecular Metabolism. 53, 101327.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation
Landy, M. A., Goyal, M., Casey, K. M., Liu, C. & Lai, H. C., Mar 30 2021, In: Cell Reports. 34, 13, 108913.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Maintenance of quiescent oocytes by noradrenergic signals
Kim, J., Hyun, M., Hibi, M. & You, Y. J., Dec 2021, In: Nature communications. 12, 1, 6925.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
PERK in POMC neurons connects celastrol with metabolism
He, Z., Lieu, L., Dong, Y., Afrin, S., Chau, D., Kabahizi, A., Wallace, B., Cao, J., Hwang, E. S., Yao, T., Huang, Y., Okolo, J., Cheng, B., Gao, Y., Hu, L. & Williams, K. W., Sep 22 2021, In: JCI Insight. 6, 18, e145306.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Regulation of Satiety Quiescence by Neuropeptide Signaling in Caenorhabditis elegans
Makino, M., Ulzii, E., Shirasaki, R., Kim, J. & You, Y. J., Jul 15 2021, In: Frontiers in Neuroscience. 15, 678590.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
The microbiota coordinates diurnal rhythms in innate immunity with the circadian clock
Brooks, J. F., Behrendt, C. L., Ruhn, K. A., Lee, S., Raj, P., Takahashi, J. S. & Hooper, L. V., Aug 5 2021, In: Cell. 184, 16, p. 4154-4167.e12Research output: Contribution to journal › Article › peer-review
Open Access85 Scopus citations -
The Phantom Satiation Hypothesis of Bariatric Surgery
Gautron, L., Feb 1 2021, In: Frontiers in Neuroscience. 15, 626085.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Time and metabolic state-dependent effects of GLP-1R agonists on NPY/AgRP and POMC neuronal activity in vivo
Dong, Y., Carty, J., Goldstein, N., He, Z., Hwang, E., Chau, D., Wallace, B., Kabahizi, A., Lieu, L., Peng, Y., Gao, Y., Hu, L., Betley, J. N. & Williams, K. W., Dec 2021, In: Molecular Metabolism. 54, 101352.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
TLR4 signaling selectively and directly promotes CGRP release from Vagal afferents in the mouse
Jia, L., Lee, S., Tierney, J. A., Elmquist, J. K., Burton, M. D. & Gautron, L., Jan 1 2021, In: eNeuro. 8, 1, p. 1-16 16 p., ENEURO.0254-20.2020.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Vagal neuron expression of the microbiota-derived metabolite receptor, free fatty acid receptor (FFAR3), is necessary for normal feeding behavior
Cook, T. M., Gavini, C. K., Jesse, J., Aubert, G., Gornick, E., Bonomo, R., Gautron, L., Layden, B. T. & Mansuy-Aubert, V., Dec 2021, In: Molecular Metabolism. 54, 101350.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations