Immunology - Wakeland Lab

Research output

Research output per year 1990 2004 2006 2007 2008 2010 2011 2023

• 132 Article
• 2 Chapter
• 2 Comment/debate
• 2 Review article
• 2 More
  • 1 Letter
  • 1 Short survey

Research output per year

Research output per year

Search results

• 2023

  Macrophages regulate gastrointestinal motility through complement component 1q

  Pendse, M., De Selle, H., Vo, N., Quinn, G., Dende, C., Li, Y., Salinas, C. N., Srinivasan, T., Propheter, D. C., Crofts, A. A., Koo, E., Hassell, B., Ruhn, K. A., Raj, P., Obata, Y. & Hooper, L. V., Apr 2023, In: eLife. 12, e78558.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Complement C1q 100%
  • Enteric Coating 89%
  • Gastrointestinal Motility 80%
  • Macrophages 46%
  • Neurogenic 37%
  3 Scopus citations
• 2022

  Association between Antibiotic Exposure and Systemic Immune Parameters in Cancer Patients Receiving Checkpoint Inhibitor Therapy

  von Itzstein, M. S., Gonugunta, A. S., Sheffield, T., Homsi, J., Dowell, J. E., Koh, A. Y., Raj, P., Fattah, F., Wang, Y., Basava, V. S., Khan, S., Park, J. Y., Popat, V., Saltarski, J. M., Gloria-Mccutchen, Y., Hsiehchen, D., Ostmeyer, J., Xie, Y., Li, Q., Wakeland, E. K., & 1 othersGerber, D. E., Mar 1 2022, In: Cancers. 14, 5, 1327.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Anti-Bacterial Agents 100%
  • nucleolin 66%
  • Antibodies 60%
  • Neoplasms 49%
  • Cytokines 40%
  9 Scopus citations
• 2021

  Impact of Bead-Beating Intensity on the Genus- and Species-Level Characterization of the Gut Microbiome Using Amplicon and Complete 16S rRNA Gene Sequencing

  Zhang, B., Brock, M., Arana, C., Dende, C., van Oers, N. S., Hooper, L. V. & Raj, P., Oct 1 2021, In: Frontiers in Cellular and Infection Microbiology. 11, 678522.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ruminococcus 100%
  • rRNA Genes 81%
  • 16S Ribosomal RNA 81%
  • Gastrointestinal Microbiome 77%
  • Microbiota 62%
  13 Scopus citations
• 2020

  Finding a unifying SLE expression signature in a sea of heterogeneity

  Wakeland, E. & Raj, P., Jul 1 2020, In: Nature Reviews Rheumatology. 16, 7, p. 357-358 2 p.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• sncRNA-1 Is a Small Noncoding RNA Produced by Mycobacterium tuberculosis in Infected Cells That Positively Regulates Genes Coupled to Oleic Acid Biosynthesis

  Coskun, F. S., Srivastava, S., Raj, P., Dozmorov, I., Belkaya, S., Mehra, S., Golden, N. A., Bucsan, A. N., Chapagain, M. L., Wakeland, E. K., Kaushal, D., Gumbo, T. & van Oers, N. S. C., Jul 28 2020, In: Frontiers in Microbiology. 11, 1631.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Small Untranslated RNA 100%
  • Oleic Acid 95%
  • Mycobacterium tuberculosis 80%
  • Genes 33%
  • RNA 21%
  3 Scopus citations

• Transcriptional profiling identifies caspase-1 as a T cell–intrinsic regulator of Th17 differentiation

  Gao, Y., Deason, K., Jain, A., Irizarry-Caro, R. A., Dozmorov, I., Coughlin, L. A., Rauch, I., Evers, B. M., Koh, A. Y., Wakeland, E. K. & Pasare, C., 2020, In: Journal of Experimental Medicine. 217, 4, e20190476.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Caspase 1 100%
  • Th17 Cells 80%
  • T-Lymphocytes 50%
  • Dendritic Cells 48%
  • Cell Differentiation 33%
  15 Scopus citations
• 2019

  FOXN1 compound heterozygous mutations cause selective thymic hypoplasia in humans

  Du, Q., Huynh, L. K., Coskun, F., Molina, E., King, M. A., Raj, P., Khan, S., Dozmorov, I., Seroogy, C. M., Wysocki, C. A., Padron, G. T., Yates, T. R., Louise Markert, M., Teresa de la Morena, M. & van Oers, N. S. C., Nov 1 2019, In: Journal of Clinical Investigation. 129, 11, p. 4724-4738 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mutation 100%
  • Nails 45%
  • Hair 44%
  • Phenotype 40%
  • Epithelial Cells 31%
  30 Scopus citations

• Immune dysregulation in cancer patients developing immune-related adverse events

  Khan, S., Khan, S., Luo, X., Fattah, F. J., Saltarski, J., Gloria-McCutchen, Y., Lu, R., Xie, Y., Li, Q., Wakeland, E. K. & Gerber, D. E., Jan 8 2019, In: British journal of cancer. 120, 1, p. 63-68 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neoplasms 100%
  • Cytokines 72%
  • atezolizumab 61%
  • Therapeutics 38%
  • Interleukin-10 34%
  121 Scopus citations

• MIR205HG Is a Long Noncoding RNA that Regulates Growth Hormone and Prolactin Production in the Anterior Pituitary

  Du, Q., Hoover, A. R., Dozmorov, I., Raj, P., Khan, S., Molina, E., Chang, T. C., de la Morena, M. T., Cleaver, O. B., Mendell, J. T. & van Oers, N. S. C., May 20 2019, In: Developmental cell. 49, 4, p. 618-631.e5

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Prolactin 100%
  • Growth Hormone 90%
  • Long Noncoding RNA 75%
  • MicroRNA 36%
  • MicroRNAs 25%
  30 Scopus citations
• 2018

  A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus

  Patel, Z. H., Lu, X., Miller, D., Forney, C. R., Lee, J., Lynch, A., Schroeder, C., Parks, L., Magnusen, A. F., Chen, X., Pujato, M., Maddox, A., Zoller, E. E., Namjou, B., Brunner, H. I., Henrickson, M., Huggins, J. L., Williams, A. H., Ziegler, J. T., Comeau, M. E., & 49 othersMarion, M. C., Glenn, S. B., Adler, A., Shen, N., Nath, S. K., Stevens, A. M., Freedman, B. I., Pons-Estel, B. A., Tsao, B. P., Jacob, C. O., Kamen, D. L., Brown, E. E., Gilkeson, G. S., Alarcón, G. S., Martin, J., Reveille, J. D., Anaya, J. M., James, J. A., Sivils, K. L., Criswell, L. A., Vilá, L. M., Petri, M., Scofield, R. H., Kimberly, R. P., Edberg, J. C., Ramsey-Goldman, R., Bang, S. Y., Lee, H. S., Bae, S. C., Boackle, S. A., Graham, D. C., Vyse, T. J., Merrill, J. T., Niewold, T. B., Ainsworth, H. C., Silverman, E. D., Weisman, M. H., Wallace, D. J., Raj, P., Guthridge, J. M., Gaffney, P. M., Kelly, J. A., Alarcón-Riquelme, M. E., Langefeld, C. D., Wakeland, E. K., Kaufman, K. M., Weirauch, M. T., Harley, J. B. & Kottyan, L. C., Jul 1 2018, In: Human molecular genetics. 27, 13, p. 2392-2404 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Alleles 100%
  • AT-Hook Motifs 45%
  • B-Lymphocytes 42%
  • Transcription Factors 41%
  • Genetic Databases 35%
  28 Scopus citations

• Co-circulation dynamics and persistence of newly introduced clades of 2012 outbreak associated West Nile Virus in Texas, 2012–2015

  Aroh, C., Liang, C., Raj, P., Wakeland, B., Yan, N. & Wakeland, E., Dec 1 2018, In: Infection, Genetics and Evolution. 66, p. 13-17 5 p.

  Research output: Contribution to journal › Article › peer-review

  • West Nile virus 100%
  • Satellite Viruses 90%
  • Disease Outbreaks 59%
  • persistence 56%
  • ecological niche 17%

• Drug-penetration gradients associated with acquired drug resistance in patients with tuberculosis

  Dheda, K., Lenders, L., Magombedze, G., Srivastava, S., Raj, P., Arning, E., Ashcraft, P., Bottiglieri, T., Wainwright, H., Pennel, T., Linegar, A., Moodley, L., Pooran, A., Pasipanodya, J. G., Sirgel, F. A., Van Helden, P. D., Wakeland, E. K., Warren, R. M. & Gumbo, T., Nov 1 2018, In: American journal of respiratory and critical care medicine. 198, 9, p. 1208-1219 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Drug Resistance 100%
  • Tuberculosis 89%
  • Pharmaceutical Preparations 45%
  • Sputum 30%
  • Anti-Bacterial Agents 30%
  106 Scopus citations

• The impact of Staphylococcus aureus genomic variation on clinical phenotype of children with acute hematogenous osteomyelitis

  Collins, A., Wakeland, E. K., Raj, P., Kim, M. S., Kim, J., Tareen, N. G. & Copley, L. A. B., Jun 2018, In: Heliyon. 4, 6, e00674.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Osteomyelitis 100%
  • Staphylococcus aureus 79%
  • Virulence 70%
  • Phenotype 55%
  • Child 40%
  7 Scopus citations
• 2017

  Distinct patterns of innate immune activation by clinical isolates of respiratory syncytial virus

  Levitz, R., Gao, Y., Dozmorov, I., Song, R., Wakeland, E. K. & Kahn, J., Sep 2017, In: PloS one. 12, 9, e0184318.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Respiratory Syncytial Viruses 100%
  • Interleukin-6 32%
  • Cercopithecine Herpesvirus 1 28%
  • Viruses 28%
  • Macrophages 22%
  20 Scopus citations

• Linezolid dose that maximizes sterilizing effect while minimizing toxicity and resistance emergence for tuberculosis

  Srivastava, S., Magombedze, G., Koeuth, T., Sherman, C., Pasipanodya, J. G., Raj, P., Wakeland, E., Deshpande, D. & Gumbo, T., Aug 2017, In: Antimicrobial agents and chemotherapy. 61, 8, e00751.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Linezolid 100%
  • Tuberculosis 64%
  • Whole Genome Sequencing 9%
  • RNA Sequence Analysis 8%
  • Pharmacokinetics 5%
  85 Scopus citations

• RAD51 interconnects between DNA replication, DNA repair and immunity

  Bhattacharya, S., Srinivasan, K., Abdisalaam, S., Su, F., Raj, P., Dozmorov, I., Mishra, R., Wakeland, E. K., Ghose, S., Mukherjee, S. & Asaithamby, A., May 5 2017, In: Nucleic acids research. 45, 8, p. 4590-4605 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • DNA Replication 100%
  • DNA Repair 92%
  • Innate Immunity 92%
  • Immunity 81%
  • Exonucleases 33%
  124 Scopus citations

• Transancestral mapping and genetic load in systemic lupus erythematosus

  Langefeld, C. D., Ainsworth, H. C., Graham, D. S. C., Kelly, J. A., Comeau, M. E., Marion, M. C., Howard, T. D., Ramos, P. S., Croker, J. A., Morris, D. L., Sandling, J. K., Almlöf, J. C., Acevedo-Vásquez, E. M., Alarcón, G. S., Babini, A. M., Baca, V., Bengtsson, A. A., Berbotto, G. A., Bijl, M., Brown, E. E., & 88 othersBrunner, H. I., Cardiel, M. H., Catoggio, L., Cervera, R., Cucho-Venegas, J. M., Dahlqvist, S. R., D'Alfonso, S., Da Silva, B. M., De La RúaFigueroa, I., Doria, A., Edberg, J. C., Endreffy, E., Esquivel-Valerio, J. A., Fortin, P. R., Freedman, B. I., Frostegård, J., Garcýá, M. A., De La Torre, I. G., Gilkeson, G. S., Gladman, D. D., Gunnarsson, I., Guthridge, J. M., Huggins, J. L., James, J. A., Kallenberg, C. G. M., Kamen, D. L., Karp, D. R., Kaufman, K. M., Kottyan, L. C., Kovács, L., Laustrup, H., Lauwerys, B. R., Li, Q. Z., Maradiaga-Ceceną, M. A., Martín, J., McCune, J. M., McWilliams, D. R., Merrill, J. T., Miranda, P., Moctezuma, J. F., Nath, S. K., Niewold, T. B., Orozco, L., Ortego-Centeno, N., Petri, M., Pineau, C. A., Pons-Estel, B. A., Pope, J., Raj, P., Ramsey-Goldman, R., Reveille, J. D., Russell, L. P., Sabio, J. M., Aguilar-Salinas, C. A., Scherbarth, H. R., Scorza, R., Seldin, M. F., Sjöwall, C., Svenungsson, E., Thompson, S. D., Toloza, S. M. A., Truedsson, L., Tusié-Luna, T., Vasconcelos, C., Vilá, L. M., Wallace, D. J., Weisman, M. H., Wither, J. E., Bhangale, T., Oksenberg, J. R., Rioux, J. D., Gregersen, P. K., Syvänen, A. C., Rönnblom, L., Criswell, L. A., Jacob, C. O., Sivils, K. L., Tsao, B. P., Schanberg, L. E., Behrens, T. W., Silverman, E. D., Alarcón-Riquelme, M. E., Kimberly, R. P., Harley, J. B., Wakeland, E. K., Graham, R. R., Gaffney, P. M. & Vyse, T. J., Jul 17 2017, In: Nature communications. 8, 16021.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Genetic Load 100%
  • Systemic Lupus Erythematosus 56%
  • Hispanic Americans 19%
  • Autoimmune Diseases 17%
  • histories 16%
  267 Scopus citations
• 2016

  DNA polymerase-α regulates the activation of type i interferons through cytosolic RNA:DNA synthesis

  Starokadomskyy, P., Gemelli, T., Rios, J. J., Xing, C., Wang, R. C., Li, H., Pokatayev, V., Dozmorov, I., Khan, S., Miyata, N., Fraile, G., Raj, P., Xu, Z., Xu, Z., Ma, L., Lin, Z., Wang, H., Yang, Y., Ben-Amitai, D., Orenstein, N., & 11 othersMussaffi, H., Baselga, E., Tadini, G., Grunebaum, E., Sarajlija, A., Krzewski, K., Wakeland, E. K., Yan, N., De La Morena, M. T., Zinn, A. R. & Burstein, E., May 1 2016, In: Nature immunology. 17, 5, p. 495-504 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Interferon Type I 100%
  • DNA-Directed DNA Polymerase 94%
  • Nucleic Acids 82%
  • Interferons 77%
  • Catalytic DNA 62%
  110 Scopus citations

• Erratum: Personalized immunomonitoring uncovers molecular networks that stratify lupus patients ((Cell (2016) 165 (551-565))

  Banchereau, R., Hong, S., Cantarel, B., Baldwin, N., Baisch, J., Edens, M., Cepika, A. M., Acs, P., Turner, J., Anguiano, E., Vinod, P., Khan, S., Obermoser, G., Blankenship, D., Wakeland, E., Nassi, L., Gotte, A., Punaro, M., Liu, Y. J., Banchereau, J., & 3 othersRossello-Urgell, J., Wright, T. & Pascual, V., Jun 2 2016, In: Cell. 165, 6, p. 1548-1550 3 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access
  84 Scopus citations

• Fatty acid amide hydrolase regulates peripheral B cell receptor revision, polyreactivity, and B1 cells in lupus

  Pathak, S., Kumar, K. R., Kanta, H., Carr-Johnson, F., Han, J., Bashmakov, A., Faure, L., Ding, H., Vanarsa, K., Khan, S., Li, Q. Z., Chapman, K., Wakeland, E. K. & Mohan, C., Feb 15 2016, In: Journal of Immunology. 196, 4, p. 1507-1516 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • fatty-acid amide hydrolase 100%
  • B-Lymphocytes 51%
  • Autoantibodies 31%
  • Central Tolerance 25%
  • Tissue Array Analysis 24%
  11 Scopus citations

• MicroRNA-205 maintains T cell development following stress by regulating forkhead box N1 and selected chemokines

  Hoover, A. R., Dozmorov, I., MacLeod, J., Du, Q., De La Teresa Morena, M., Forbess, J., Guleserian, K., Cleaver, O. B. & Van Oers, N. S. C., Oct 28 2016, In: Journal of Biological Chemistry. 291, 44, p. 23237-23247 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Chemokines 100%
  • MicroRNAs 89%
  • T-Lymphocytes 65%
  • MicroRNA 65%
  • Stem Cell Factor 64%
  19 Scopus citations

• Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity

  Raj, P., Rai, E., Song, R., Khan, S., Wakeland, B. E., Viswanathan, K., Arana, C., Liang, C., Zhang, B., Dozmorov, I., Carr-Johnson, F., Mitrovic, M., Wiley, G. B., Kelly, J. A., Lauwerys, B. R., Olsen, N. J., Cotsapas, C., Garcia, C. K., Wise, C. A., Harley, J. B., & 9 othersNath, S. K., James, J. A., Jacob, C. O., Tsao, B. P., Pasare, C., Karp, D. R., Li, Q. Z., Gaffney, P. M. & Wakeland, E. K., Feb 15 2016, In: eLife. 5, FEBRUARY2016, e12089.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Autoimmunity 100%
  • Systemic Lupus Erythematosus 96%
  • Binding Site 72%
  • HLA-DQA1 antigen 39%
  • HLA-D Antigens 37%
  97 Scopus citations

• RNA sequencing reveals the consequences of a novel insertion in dedicator of cytokinesis-8

  Khan, S., Kuruvilla, M., Hagin, D., Wakeland, B., Liang, C., Vishwanathan, K., Gatti, R. A., Torgersen, T. R., Abraham, R. S., Wakeland, E. K., van Oers, N. S. C. & de la Morena, M. T., Jul 1 2016, In: Journal of Allergy and Clinical Immunology. 138, 1, p. 289-292.e6

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations
• 2015

  A genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpression

  Shields, B. B., Pecot, C. V., Gao, H., McMillan, E., Potts, M., Nagel, C., Purinton, S., Wang, Y., Ivan, C., Kim, H. S., Borkowski, R. J., Khan, S., Rodriguez-Aguayo, C., Lopez-Berestein, G., Lea, J., Gazdar, A., Baggerly, K. A., Sood, A. K. & White, M. A., Dec 1 2015, In: Molecular Systems Biology. 11, 12, p. 1-17 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • MicroRNA 100%
  • Ovarian Cancer 97%
  • ovarian neoplasms 87%
  • Genome 67%
  • Genomics 63%
  8 Scopus citations

• Cutting edge: Inhibiting TBK1 by compound II ameliorates autoimmune disease in mice

  Hasan, M., Dobbs, N., Khan, S., White, M. A., Wakeland, E. K., Li, Q. Z. & Yan, N., Nov 15 2015, In: Journal of Immunology. 195, 10, p. 4573-4577 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Autoimmune Diseases 100%
  • Phosphotransferases 89%
  • Systemic Lupus Erythematosus 31%
  • Poly I-C 21%
  • Protein-Serine-Threonine Kinases 18%
  60 Scopus citations

• Differential outcome of TRIF-mediated signaling in TLR4 and TLR3 induced DC maturation

  Hu, W., Jain, A., Gao, Y., Dozmorov, I. M., Mandraju, R., Wakeland, E. K. & Pasare, C., Nov 10 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 45, p. 13994-13999 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dendritic Cells 100%
  • Interferon Regulatory Factor-3 41%
  • Myeloid Differentiation Factor 88 20%
  • Toll-Like Receptor 3 19%
  • Pathogen-Associated Molecular Pattern Molecules 18%
  52 Scopus citations

• Ribosomal and immune transcripts associate with relapse in acquired ADAMTS13-deficient thrombotic thrombocytopenic purpura

  Edgar, C. E., Terrell, D. R., Vesely, S. K., Wren, J. D., Dozmorov, I. M., Niewold, T. B., Brown, M., Zhou, F., Frank, M. B., Merrill, J. T., Kremer Hovinga, J. A., Lä Mmle, B., James, J. A., George, J. N. & Farris, A. D., Feb 11 2015, In: PloS one. 10, 2, e0117614.

  Research output: Contribution to journal › Article › peer-review

  • Thrombotic Thrombocytopenic Purpura 100%
  • Recurrence 42%
  • Autoantibodies 38%
  • Interferon Type I 19%
  • RNA-Binding Proteins 19%
  3 Scopus citations

• RNA sensing by conventional dendritic cells is central to the development of lupus nephritis

  Celhar, T., Hopkins, R., Thornhill, S. I., De Magalhaes, R., Hwang, S. H., Lee, H. Y., Yasuga, H., Jones, L. A., Casco, J., Lee, B., Thamboo, T. P., Zhou, X. J., Poidinger, M., Connolly, J. E., Wakeland, E. K. & Fairhurst, A. M., Nov 10 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 45, p. E6195-E6204

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Toll-Like Receptor 7 100%
  • Lupus Nephritis 82%
  • Dendritic Cells 60%
  • RNA 46%
  • Systemic Lupus Erythematosus 38%
  44 Scopus citations

• RNA Seq profiling reveals a novel expression pattern of TGF-β target genes in human blood eosinophils

  Shen, Z. J., Hu, J., Esnault, S., Dozmorov, I. & Malter, J. S., Sep 1 2015, In: Immunology Letters. 167, 1, p. 1-10 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • RNA-Seq 100%
  • Eosinophils 82%
  • Genes 34%
  • Asthma 22%
  • Airway Remodeling 18%
  29 Scopus citations
• 2014

  Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations

  Kim-Howard, X., Sun, C., Molineros, J. E., Maiti, A. K., Chandru, H., Adler, A., Wiley, G. B., Kaufman, K. M., Kottyan, L., Guthridge, J. M., Rasmussen, A., Kelly, J., Sánchez, E., Raj, P., Li, Q. Z., Bang, S. Y., Lee, H. S., Kim, T. H., Kang, Y. M., Suh, C. H., & 35 othersChung, W. T., Park, Y. B., Choe, J. Y., Shim, S. C., Lee Shin-Seok, S. S., Han, B. G., Olsen, N. J., Karp, D. R., Moser, K., Pons-Estel, B. A., Wakeland, E. K., James, J. A., Harley, J. B., Bae, S. C., Gaffney, P. M., Alarcón-Riquelme, M., Acevedo, E., La Torre, I. G. D., Maradiaga-Ceceña, M. A., Cardiel, M. H., Esquivel-Valerio, J. A., Rodriguez-Amado, J., Moctezuma, J. F., Miranda, P., Perandones, C., Castel, C., Laborde, H. A., Alba, P., Musuruana, J., Goecke, A., Foster, C., Orozco, L., Baca, V., Looger, L. L. & Nath, S. K., Mar 2014, In: Human molecular genetics. 23, 6, p. 1656-1668 13 p., ddt532.

  Research output: Contribution to journal › Article › peer-review

  • Systemic Lupus Erythematosus 100%
  • Single Nucleotide Polymorphism 89%
  • Hispanic Americans 81%
  • African Americans 59%
  • NADPH Oxidases 48%
  62 Scopus citations

• Dysregulated cytokine production by dendritic cells modulates B cell responses in the NZM2410 mouse model of lupus

  Sang, A., Zheng, Y. Y., Yin, Y., Dozmorov, I., Li, H., Hsu, H. C., Mountz, J. D. & Morel, L., Aug 5 2014, In: PloS one. 9, 8, e102151.

  Research output: Contribution to journal › Article › peer-review

  • Dendritic Cells 100%
  • B-Lymphocytes 86%
  • Cytokines 69%
  • Interleukin-6 34%
  • Interferons 20%
  27 Scopus citations

• Erratum: The Indian origin of paternal haplogroup R1a1* substantiates the autochthonous origin of Brahmins and the caste system (Journal of Human Genetics (2014) 59 (415-416) DOI:10.1038/jhg.2014.42)

  Sharma, S., Rai, E., Sharma, P., Jena, M., Singh, S., Darvishi, K., Bhat, A. K., Bhanwer, A. J. S., Tiwari, P. K. & Bamezai, R. N. K., Jul 2014, In: Journal of Human Genetics. 59, 7, p. 415-416 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

• NOS2A promoter (CCTTT)_n association with TB lacks independent functional correlation amongst Indians

  Jena, M., Srivastava, A. K., Singh, R. K., Sharma, P. R., Das, P. K. & Bamezai, R. N. K., Jan 2014, In: Tuberculosis. 94, 1, p. 81-86 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Microsatellite Repeats 100%
  • Tuberculosis 78%
  • Rubiaceae 43%
  • Reporter Genes 31%
  • Genetic Promoter Regions 30%
  2 Scopus citations

• T/B-cell interactions are more transient in response to weak stimuli in SLE-prone mice

  Sinai, P., Dozmorov, I. M., Song, R., Schwartzberg, P. L., Wakeland, E. K. & Wülfing, C., Dec 2014, In: European Journal of Immunology. 44, 12, p. 3522-3531 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Systemic Lupus Erythematosus 100%
  • Cell Communication 99%
  • B-Lymphocytes 81%
  • T-Lymphocytes 43%
  • Antinuclear Antibodies 20%
  17 Scopus citations
• 2013

  Evidence of Dynamically Dysregulated Gene Expression Pathways in Hyperresponsive B Cells from African American Lupus Patients

  Dozmorov, I., Dominguez, N., Sestak, A. L., Robertson, J. M., Harley, J. B., James, J. A. & Guthridge, J. M., Aug 15 2013, In: PloS one. 8, 8, e71397.

  Research output: Contribution to journal › Article › peer-review

  • B-lymphocytes 100%
  • African Americans 95%
  • B-Lymphocytes 78%
  • gene expression 61%
  • Gene Expression 60%
  3 Scopus citations

• Signature MicroRNA expression patterns identified in humans with 22q11.2 deletion/DiGeorge syndrome

  De la Morena, M. T., Eitson, J. L., Dozmorov, I. M., Belkaya, S., Hoover, A. R., Anguiano, E., Pascual, M. V. & van Oers, N. S. C., Apr 2013, In: Clinical Immunology. 147, 1, p. 11-22 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • DiGeorge Syndrome 100%
  • MicroRNAs 61%
  • Hypocalcemia 19%
  • Chromosome Deletion 10%
  • Regulator Genes 8%
  54 Scopus citations

• Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes

  Hasan, M., Koch, J., Rakheja, D., Pattnaik, A. K., Brugarolas, J. B., Dozmorov, I., Levine, B., Wakeland, E. K., Lee-Kirsch, M. A. & Yan, N., Jan 2013, In: Nature immunology. 14, 1, p. 61-71 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Interferons 100%
  • Transcriptional Activation 99%
  • Antiviral Agents 93%
  • three prime repair exonuclease 1 32%
  • Genes 25%
  119 Scopus citations

• XBeclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism

  He, C., Wei, Y., Sun, K., Li, B., Dong, X., Zou, Z., Liu, Y., Kinch, L. N., Khan, S., Sinha, S., Xavier, R. J., Grishin, N. V., Xiao, G., Eskelinen, E. L., Scherer, P. E., Whistler, J. L. & Levine, B., Aug 29 2013, In: Cell. 154, 5, p. X1085-1099

  Research output: Contribution to journal › Article › peer-review

  • Cannabinoid 100%
  • Insulin Derivative 80%
  • G-Protein-Coupled Receptors 79%
  • Autophagy 75%
  • Pharmacological Metabolism 61%
  127 Scopus citations
• 2012

  Chemical-induced estrogenicity

  Safe, S. H., Khan, S., Wu, F., Li, X. & Sreevalsan, S., 2012, Veterinary Toxicology. Elsevier Inc., p. 999-1011 13 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  2 Scopus citations

• External Qi of Yan Xin Qigong induces cell death and gene expression alterations promoting apoptosis and inhibiting proliferation, migration and glucose metabolism in small-cell lung cancer cells

  Yan, X., Li, F., Dozmorov, I., Frank, M. B., Dao, M., Centola, M., Cao, W. & Hu, D., Apr 2012, In: Molecular and Cellular Biochemistry. 363, 1-2, p. 245-255 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Qigong 100%
  • Qi 86%
  • Small Cell Lung Carcinoma 70%
  • Cell Death 67%
  • Pharmacological Metabolism 49%
  22 Scopus citations

• Genetic polymorphisms of CCL2, CCL5, CCR2 and CCR5 genes in Sahariya tribe of North Central India: An association study with pulmonary tuberculosis

  Mishra, G., Poojary, S. S., Raj, P. & Tiwari, P. K., Jul 2012, In: Infection, Genetics and Evolution. 12, 5, p. 1120-1127 8 p.

  Research output: Contribution to journal › Article › peer-review

  • tuberculosis 100%
  • polymorphism 79%
  • Genetic Polymorphisms 79%
  • Pulmonary Tuberculosis 78%
  • India 66%
  33 Scopus citations

• Murine lupus susceptibility locus Sle1c2 mediates CD4⁺ T cell activation and maps to estrogen-related receptor γ

  Perry, D. J., Yin, Y., Telarico, T., Baker, H. V., Dozmorov, I., Perl, A. & Morel, L., Jul 15 2012, In: Journal of Immunology. 189, 2, p. 793-803 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptors 100%
  • T-Lymphocytes 66%
  • Graft vs Host Disease 22%
  • Orphan Nuclear Receptors 15%
  • Congenic Mice 14%
  57 Scopus citations

• Pre-B cell leukemia homeobox 1 is associated with lupus susceptibility in mice and humans

  Cuda, C. M., Li, S., Liang, S., Yin, Y., Potula, H. H. S. K., Xu, Z., Sengupta, M., Chen, Y., Butfiloski, E., Baker, H., Chang, L. J., Dozmorov, I., Sobel, E. S. & Morel, L., Jan 15 2012, In: Journal of Immunology. 188, 2, p. 604-614 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Homeobox Genes 74%
  • T-Lymphocytes 39%
  • Tretinoin 21%
  • Regulatory T-Lymphocytes 21%
  30 Scopus citations

• Prevalence of smear-positive pulmonary tuberculosis in different ethnic groups in India: Evaluation of public health

  Raj, P., Prakash, R., Mishra, G., Singh, T. D., Poojary, S., Mehra, N. K. & Tiwari, P. K., Apr 2012, In: Public Health. 126, 4, p. 295-299 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Pulmonary Tuberculosis 100%
  • contagious disease 93%
  • India 84%
  • ethnic group 76%
  • Population Groups 74%
  13 Scopus citations
• 2011

  Activation of nuclear TR3 (NR4A1) by a diindolylmethane analog induces apoptosis and proapoptotic genes in pancreatic cancer cells and tumors

  Yoon, K., Lee, S. O., Cho, S. D., Kim, K., Khan, S. & Safe, S., Jun 2011, In: Carcinogenesis. 32, 6, p. 836-842 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 3,3'-diindolylmethane 100%
  • Pancreatic Neoplasms 56%
  • Activating Transcription Factor 3 38%
  • Apoptosis 36%
  • Growth 30%
  70 Scopus citations

• Anthrax Lethal Toxin-induced gene expression changes in mouse lung

  Dumas, E. K., Cox, P. M., Fullenwider, C. O. C., Nguyen, M., Centola, M., Frank, M. B., Dozmorov, I., James, J. A. & Darise Farris, A., Sep 2011, In: Toxins. 3, 9, p. 1111-1130 20 p.

  Research output: Contribution to journal › Article › peer-review

  • anthrax toxin 100%
  • Lethal 81%
  • Toxin 65%
  • Gene Expression 40%
  • Lung 36%
  5 Scopus citations

• Coding and non-coding polymorphisms in VDR gene and susceptibility to pulmonary tuberculosis in tribes, castes and Muslims of Central India

  Sharma, P. R., Singh, S., Jena, M., Mishra, G., Prakash, R., Das, P. K., Bamezai, R. N. K. & Tiwari, P. K., Aug 2011, In: Infection, Genetics and Evolution. 11, 6, p. 1456-1461 6 p.

  Research output: Contribution to journal › Article › peer-review

  • calcitriol receptors 100%
  • caste 91%
  • Muslims 86%
  • tuberculosis 82%
  • Islam 81%
  44 Scopus citations

• Cyclin-dependent kinase inhibitor Cdkn2c regulates B cell homeostasis and function in the NZM2410-derived murine lupus susceptibility locus Sle2c1

  Xu, Z., Potula, H. H. S. K., Vallurupalli, A., Perry, D., Baker, H., Croker, B. P., Dozmorov, I. & Morel, L., Jun 15 2011, In: Journal of Immunology. 186, 12, p. 6673-6682 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Cyclin-Dependent Kinases 100%
  • B-Lymphocytes 65%
  • Homeostasis 62%
  • Peritoneal Cavity 27%
  • G1 Phase Cell Cycle Checkpoints 15%
  29 Scopus citations

• DAZL 260A>G and MTHFR 677C>T variants in sperm DNA of infertile

  Kumar, K., Venkatesh, S., Sharma, P. R., Tiwari, P. K. & Dada, R., Dec 2011, In: Indian Journal of Biochemistry and Biophysics. 48, 6, p. 422-426 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Tetrahydrofolate 100%
  • Methylenetetrahydrofolate Reductase (NADPH2) 89%
  • Azoospermia 87%
  • Spermatozoa 64%
  • DNA 38%
  17 Scopus citations

• Identification of outcome-correlated cytokine clusters in chronic lymphocytic leukemia

  Yan, X. J., Dozmorov, I., Li, W., Yancopoulos, S., Sison, C., Centola, M., Jain, P., Allen, S. L., Kolitz, J. E., Rai, K. R., Chiorazzi, N. & Sherry, B., Nov 10 2011, In: Blood. 118, 19, p. 5201-5210 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • B-Cell Chronic Lymphocytic Leukemia 100%
  • Indicator 82%
  • Mutation 79%
  • Serum Level 64%
  • Molecular Cluster 60%
  96 Scopus citations