Research output per year
Research output per year
- 23 results
Search results
-
2018
BCAP links IL-1R to the PI3K-mTOR pathway and regulates pathogenic Th17 cell differentiation
Deason, K., Troutman, T. D., Jain, A., Challa, D. K., Mandraju, R., Brewer, T., Ward, E. S. & Pasare, C., 2018, In: Journal of Experimental Medicine. 215, 9, p. 2413-2428 16 p.Research output: Contribution to journal › Article › peer-review
Open Access42 Scopus citations -
MyD88 signaling in T cells is critical for effector CD4 T cell differentiation following a transitional T follicular helper cell stage
Mandraju, R., Jain, A., Gao, Y., Ouyang, Z., Norgard, M. V. & Pasare, C., May 1 2018, In: Infection and immunity. 86, 5, e00791-17.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Regulation of contact sensitivity in non-obese diabetic (NOD) mice by innate immunity
Szczepanik, M., Majewska-Szczepanik, M., Wong, F. S., Kowalczyk, P., Pasare, C. & Wen, L., Oct 2018, In: Contact Dermatitis. 79, 4, p. 197-207 11 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
T cell-intrinsic IL-1R signaling licenses effector cytokine production by memory CD4 T cells
Jain, A., Song, R., Wakeland, E. K. & Pasare, C., Dec 1 2018, In: Nature communications. 9, 1, 3185.Research output: Contribution to journal › Article › peer-review
Open Access70 Scopus citations -
2017
Inhibition of IRAK1 ubiquitination determines glucocorticoid sensitivity for tlr9-induced inflammation in macrophages
Kong, F., Liu, Z., Jain, V. G., Shima, K., Suzuki, T., Muglia, L. J., Starczynowski, D. T., Pasare, C. & Bhattacharyya, S., Nov 15 2017, In: Journal of Immunology. 199, 10, p. 3654-3667 14 p.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
2016
ARC Syndrome-Linked Vps33B Protein Is Required for Inflammatory Endosomal Maturation and Signal Termination
Akbar, M. A., Mandraju, R., Tracy, C., Hu, W., Pasare, C. & Krämer, H., 2016, In: Immunity. 45, 2, p. 267-279 13 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Comprehensive RNAi-based screening of human and mouse TLR pathways identifies species-specific preferences in signaling protein use
Sun, J., Li, N., Oh, K. S., Dutta, B., Vayttaden, S. J., Lin, B., Ebert, T. S., De Nardo, D., Davis, J., Bagirzadeh, R., Lounsbury, N. W., Pasare, C., Latz, E., Hornung, V. & Fraser, I. D. C., Jan 5 2016, In: Science signaling. 9, 409, ra3.Research output: Contribution to journal › Article › peer-review
Open Access57 Scopus citations -
Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity
Raj, P., Rai, E., Song, R., Khan, S., Wakeland, B. E., Viswanathan, K., Arana, C., Liang, C., Zhang, B., Dozmorov, I., Carr-Johnson, F., Mitrovic, M., Wiley, G. B., Kelly, J. A., Lauwerys, B. R., Olsen, N. J., Cotsapas, C., Garcia, C. K., Wise, C. A., Harley, J. B., & 9 others, Feb 15 2016, In: eLife. 5, FEBRUARY2016, e12089.Research output: Contribution to journal › Article › peer-review
Open Access97 Scopus citations -
2015
Differential outcome of TRIF-mediated signaling in TLR4 and TLR3 induced DC maturation
Hu, W., Jain, A., Gao, Y., Dozmorov, I. M., Mandraju, R., Wakeland, E. K. & Pasare, C., Nov 10 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 45, p. 13994-13999 6 p.Research output: Contribution to journal › Article › peer-review
Open Access52 Scopus citations -
The DNA Sensor AIM2 Maintains Intestinal Homeostasis via Regulation of Epithelial Antimicrobial Host Defense
Hu, S., Peng, L., Kwak, Y. T., Tekippe, E. M., Pasare, C., Malter, J. S., Hooper, L. V. & Zaki, M. H., Dec 1 2015, In: Cell Reports. 13, 9, p. 1922-1936 15 p.Research output: Contribution to journal › Article › peer-review
Open Access92 Scopus citations -
2014
Differential ability of surface and endosomal TLRs to Induce CD8 T Cell Responses in Vivo
Mandraju, R., Murray, S., Forman, J. & Pasare, C., May 1 2014, In: Journal of Immunology. 192, 9, p. 4303-4315 13 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
Enhancement of anti-tumor CD8 immunity by IgG1-mediated targeting of Fc receptors
Furlan, S. N., Mandraju, R., Brewer, T., Roybal, K., Troutman, T. D., Hu, W., Palm, N. W., Unni, A. & Pasare, C., Jan 2014, In: mAbs. 6, 1, p. 108-118 11 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
IRAK-1 bypasses priming and directly links TLRs torapid NLRP3 inflammasome activation
Lin, K. M., Hu, W., Troutman, T. D., Jennings, M., Brewer, T., Li, X., Nanda, S., Cohen, P., Thomas, J. A. & Pasare, C., 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 2, p. 775-780 6 p.Research output: Contribution to journal › Article › peer-review
206 Scopus citations -
2012
Role for B-cell adapter for PI3K (BCAP) as a signaling adapter linking Toll-like receptors (TLRs) to serine/threonine kinases PI3K/Akt
Troutman, T. D., Hu, W., Fulenchek, S., Yamazaki, T., Kurosaki, T., Bazand, J. F. & Pasare, C., Jan 3 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 1, p. 273-278 6 p.Research output: Contribution to journal › Article › peer-review
139 Scopus citations -
2011
Priming Microenvironments Dictate Cytokine Requirements for T Helper 17 Cell Lineage Commitment
Hu, W., Troutman, T. D., Edukulla, R. & Pasare, C., Dec 23 2011, In: Immunity. 35, 6, p. 1010-1022 13 p.Research output: Contribution to journal › Article › peer-review
88 Scopus citations -
2005
Control of B-cell responses by Toll-like receptors
Pasare, C. & Medzhitov, R., Nov 17 2005, In: Nature. 438, 7066, p. 364-368 5 p.Research output: Contribution to journal › Article › peer-review
627 Scopus citations -
Toll-like receptors: Linking innate and adaptive immunity
Pasare, C. & Medzhitov, R., 2005, In: Advances in experimental medicine and biology. 560, p. 11-18 8 p.Research output: Contribution to journal › Article › peer-review
458 Scopus citations -
2004
Toll-dependent control mechanisms of CD4 T cell activation
Pasare, C. & Medzhitov, R., Nov 2004, In: Immunity. 21, 5, p. 733-741 9 p.Research output: Contribution to journal › Article › peer-review
321 Scopus citations -
Toll-like receptors and acquired immunity
Pasare, C. & Medzhitov, R., Feb 2004, In: Seminars in Immunology. 16, 1, p. 23-26 4 p.Research output: Contribution to journal › Article › peer-review
176 Scopus citations -
2003
Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
Pasare, C. & Medzhitov, R., Feb 14 2003, In: Science. 299, 5609, p. 1033-1036 4 p.Research output: Contribution to journal › Article › peer-review
Open Access1823 Scopus citations -
2001
T cells in mice expressing a transgenic human TCRβ chain get positively selected but cannot be activated in the periphery by signaling through TCR
Pasare, C., Mukherjee, P., Verhoef, A., Bansal, P., Mendiratta, S. K., George, A., Lamb, J. R., Rath, S. & Bal, V., 2001, In: International Immunology. 13, 1, p. 53-62 10 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
1999
Expression of an immunoglobulin heavy chain transgene in macrophage as well as lymphocyte lineages in vivo
Pasare, C., Noggle, S., Entringer, M., Heinzelmann, A., Bansal, P., George, A., Bal, V., Rath, S. & Durdik, J. M., 1999, In: European Journal of Immunology. 29, 4, p. 1219-1227 9 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
1998
Presence of activated antigen-binding B cells during immunization enhances relative levels of IFN-γ in T cell responses
Pasare, C., Morafo, V., Entringer, M., Bansal, P., George, A., Bal, V., Rath, S. & Durdik, J. M., Jan 15 1998, In: Journal of Immunology. 160, 2, p. 778-787 10 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations