Children's Medical Center Research Institute At Ut Southwestern

Research output

Research output per year 1994 2011 2012 2014 2015 2016 2017 2019 2020 2021 2022 2023 2024

• 663 Article
• 95 Review article
• 35 Comment/debate
• 19 Short survey
• 37 More
  • 11 Letter
  • 10 Conference contribution
  • 9 Chapter
  • 7 Editorial

Research output per year

Research output per year

Search results

• 2023

  Apoptotic cell death in disease—Current understanding of the NCCD 2023

  Vitale, I., Pietrocola, F., Guilbaud, E., Aaronson, S. A., Abrams, J. M., Adam, D., Agostini, M., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., Aqeilan, R. I., Arama, E., Baehrecke, E. H., Balachandran, S., Bano, D., Barlev, N. A., Bartek, J., Bazan, N. G., & 208 othersBecker, C., Bernassola, F., Bertrand, M. J. M., Bianchi, M. E., Blagosklonny, M. V., Blander, J. M., Blandino, G., Blomgren, K., Borner, C., Bortner, C. D., Bove, P., Boya, P., Brenner, C., Broz, P., Brunner, T., Damgaard, R. B., Calin, G. A., Campanella, M., Candi, E., Carbone, M., Carmona-Gutierrez, D., Cecconi, F., Chan, F. K. M., Chen, G. Q., Chen, Q., Chen, Y. H., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Ciliberto, G., Conrad, M., Cubillos-Ruiz, J. R., Czabotar, P. E., D’Angiolella, V., Daugaard, M., Dawson, T. M., Dawson, V. L., De Maria, R., De Strooper, B., Debatin, K. M., Deberardinis, R. J., Degterev, A., Del Sal, G., Deshmukh, M., Di Virgilio, F., Diederich, M., Dixon, S. J., Dynlacht, B. D., El-Deiry, W. S., Elrod, J. W., Engeland, K., Fimia, G. M., Galassi, C., Ganini, C., Garcia-Saez, A. J., Garg, A. D., Garrido, C., Gavathiotis, E., Gerlic, M., Ghosh, S., Green, D. R., Greene, L. A., Gronemeyer, H., Häcker, G., Hajnóczky, G., Hardwick, J. M., Haupt, Y., He, S., Heery, D. M., Hengartner, M. O., Hetz, C., Hildeman, D. A., Ichijo, H., Inoue, S., Jäättelä, M., Janic, A., Joseph, B., Jost, P. J., Kanneganti, T. D., Karin, M., Kashkar, H., Kaufmann, T., Kelly, G. L., Kepp, O., Kimchi, A., Kitsis, R. N., Klionsky, D. J., Kluck, R., Krysko, D. V., Kulms, D., Kumar, S., Lavandero, S., Lavrik, I. N., Lemasters, J. J., Liccardi, G., Linkermann, A., Lipton, S. A., Lockshin, R. A., López-Otín, C., Luedde, T., MacFarlane, M., Madeo, F., Malorni, W., Manic, G., Mantovani, R., Marchi, S., Marine, J. C., Martin, S. J., Martinou, J. C., Mastroberardino, P. G., Medema, J. P., Mehlen, P., Meier, P., Melino, G., Melino, S., Miao, E. A., Moll, U. M., Muñoz-Pinedo, C., Murphy, D. J., Niklison-Chirou, M. V., Novelli, F., Núñez, G., Oberst, A., Ofengeim, D., Opferman, J. T., Oren, M., Pagano, M., Panaretakis, T., Pasparakis, M., Penninger, J. M., Pentimalli, F., Pereira, D. M., Pervaiz, S., Peter, M. E., Pinton, P., Porta, G., Prehn, J. H. M., Puthalakath, H., Rabinovich, G. A., Rajalingam, K., Ravichandran, K. S., Rehm, M., Ricci, J. E., Rizzuto, R., Robinson, N., Rodrigues, C. M. P., Rotblat, B., Rothlin, C. V., Rubinsztein, D. C., Rudel, T., Rufini, A., Ryan, K. M., Sarosiek, K. A., Sawa, A., Sayan, E., Schroder, K., Scorrano, L., Sesti, F., Shao, F., Shi, Y., Sica, G. S., Silke, J., Simon, H. U., Sistigu, A., Stephanou, A., Stockwell, B. R., Strapazzon, F., Strasser, A., Sun, L., Sun, E., Sun, Q., Szabadkai, G., Tait, S. W. G., Tang, D., Tavernarakis, N., Troy, C. M., Turk, B., Urbano, N., Vandenabeele, P., Vanden Berghe, T., Vander Heiden, M. G., Vanderluit, J. L., Verkhratsky, A., Villunger, A., von Karstedt, S., Voss, A. K., Vousden, K. H., Vucic, D., Vuri, D., Wagner, E. F., Walczak, H., Wallach, D., Wang, R., Wang, Y., Weber, A., Wood, W., Yamazaki, T., Yang, H. T., Zakeri, Z., Zawacka-Pankau, J. E., Zhang, L., Zhang, H., Zhivotovsky, B., Zhou, W., Piacentini, M., Kroemer, G. & Galluzzi, L., May 2023, In: Cell Death and Differentiation. 30, 5, p. 1097-1154 58 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Terminology 100%
  • Cell Death 75%
  • Apoptosis 60%
  • Regulated Cell Death 51%
  • Homeostasis 48%
  69 Scopus citations

• DNA damage in IDH-mutant gliomas: mechanisms and clinical implications

  Shi, D. D., Anand, S., Abdullah, K. & McBrayer, S. K., May 2023, In: Journal of Neuro-Oncology. 162, 3, p. 515-523 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Glioma 100%
  • DNA Damage 94%
  • Mutation 50%
  • Alkylating Agents 42%
  • Brain Neoplasms 33%
  5 Scopus citations

• Emerging roles of nucleotide metabolism in cancer

  Shi, D. D., Savani, M. R., Abdullah, K. G. & McBrayer, S. K., Aug 2023, In: Trends in Cancer. 9, 8, p. 624-635 12 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Nucleotides 100%
  • Neoplasms 40%
  • Transcriptome 19%
  • Homeostasis 15%
  • RNA 14%
  3 Scopus citations

• Isocitrate dehydrogenase mutations in gliomas: A review of current understanding and trials

  Sharma, N., Mallela, A. N., Shi, D. D., Tang, L. W., Abou-Al-Shaar, H., Gersey, Z. C., Zhang, X., Mcbrayer, S. K. & Abdullah, K., Jan 1 2023, In: Neuro-Oncology Advances. 5, 1, vdad053.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Isocitrate Dehydrogenase 100%
  • Glioma 67%
  • Mutation 41%
  • Poly(ADP-ribose) Polymerase Inhibitors 24%
  • Subunit Vaccines 22%
  6 Scopus citations

• Metabolic pathway analysis using stable isotopes in patients with cancer

  Bartman, C. R., Faubert, B., Rabinowitz, J. D. & DeBerardinis, R. J., Dec 2023, In: Nature Reviews Cancer. 23, 12, p. 863-878 16 p.

  Research output: Contribution to journal › Review article › peer-review

  • Isotopes 100%
  • Metabolic Networks and Pathways 93%
  • Neoplasms 29%
  • Nutrients 12%
  • Intrinsic Factor 8%
  5 Scopus citations

• Preclinical modeling of lower-grade gliomas

  Tang, L. W., Mallela, A. N., Deng, H., Richardson, T. E., Hervey-Jumper, S. L., McBrayer, S. K. & Abdullah, K. G., 2023, In: Frontiers in Oncology. 13, 1139383.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Glioma 100%
  • Direction compound 13%
  • Therapeutics 8%
  • Neoplasms 5%
  1 Scopus citations

• Spotlight on GOT2 in Cancer Metabolism

  Kerk, S. A., Garcia-Bermudez, J., Birsoy, K., Sherman, M. H., Shah, Y. M. & Lyssiotis, C. A., 2023, In: OncoTargets and Therapy. 16, p. 695-702 8 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Neoplasms 100%
  • Nexus 87%
  • Cell Plasticity 82%
  • Critical Pathways 72%
  • Metabolic Networks and Pathways 62%
  2 Scopus citations
• 2022

  Chromosomal instability in adult-type diffuse gliomas

  Richardson, T. E., Walker, J. M., Abdullah, K. G., McBrayer, S. K., Viapiano, M. S., Mussa, Z. M., Tsankova, N. M., Snuderl, M. & Hatanpaa, K. J., Dec 2022, In: Acta Neuropathologica Communications. 10, 1, 115.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Chromosomal Instability 100%
  • Glioma 74%
  • Neoplasms 26%
  • Chromothripsis 19%
  • Mutation 12%
  3 Scopus citations

• Creation and Development of Patient-Derived Organoids for Therapeutic Screening in Solid Cancer

  Hicks, W. H., Bird, C. E., Gattie, L. C., Shami, M. E., Traylor, J. I., Shi, D. D., McBrayer, S. K. & Abdullah, K. G., Jun 2022, In: Current Stem Cell Reports. 8, 2, p. 107-117 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Organoids 100%
  • Neoplasms 24%
  • Therapeutics 12%
  • Gastrointestinal Neoplasms 7%
  • Clinical Decision-Making 6%
  1 Scopus citations

• Metabolic analysis as a driver for discovery, diagnosis, and therapy

  DeBerardinis, R. J. & Keshari, K. R., Jul 21 2022, In: Cell. 185, 15, p. 2678-2689 12 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Metabolomics 100%
  • Organelles 86%
  • Metabolic 73%
  • Physiological Stress 54%
  • Technology 29%
  51 Scopus citations

• Metabolic regulation of somatic stem cells in vivo

  Meacham, C. E., DeVilbiss, A. W. & Morrison, S. J., Jun 2022, In: Nature Reviews Molecular Cell Biology. 23, 6, p. 428-443 16 p.

  Research output: Contribution to journal › Review article › peer-review

  • Adult Stem Cells 100%
  • Stem Cells 63%
  • Regeneration 24%
  • Homeostasis 14%
  • Lysosomes 9%
  29 Scopus citations
• 2021

  Contemporary mouse models in glioma research

  Hicks, W. H., Bird, C. E., Traylor, J. I., Shi, D. D., El Ahmadieh, T. Y., Richardson, T. E., McBrayer, S. K. & Abdullah, K. G., Mar 2021, In: Cells. 10, 3, 712.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Glioma 100%
  • Heterogeneity 99%
  • Mutation 91%
  • Isocitrate Dehydrogenase 49%
  • Brain Neoplasms 16%
  21 Scopus citations

• Extrachromosomal DNA: An Emerging Hallmark in Human Cancer

  Wu, S., Bafna, V., Chang, H. Y. & Mischel, P. S., 2021, In: Annual Review of Pathology: Mechanisms of Disease. 17, p. 367-386 20 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • DNA 100%
  • Neoplasms 57%
  • Chromosomes 47%
  • Regulator Genes 30%
  • Oncogenes 28%
  36 Scopus citations

• Metabolic Plasticity of Neutrophils: Relevance to Pathogen Responses and Cancer

  Rogers, T. & DeBerardinis, R. J., Aug 2021, In: Trends in Cancer. 7, 8, p. 700-713 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Neutrophils 100%
  • Neoplasms 41%
  • Foreign Bodies 19%
  • Tumor Microenvironment 18%
  • Metabolic Networks and Pathways 18%
  26 Scopus citations

• Molecular and metabolic mechanisms underlying selective 5-aminolevulinic acid-induced fluorescence in gliomas

  Traylor, J. I., Pernik, M. N., Sternisha, A. C., McBrayer, S. K. & Abdullah, K. G., Feb 1 2021, In: Cancers. 13, 3, p. 1-15 15 p., 580.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Aminolevulinic Acid 100%
  • Glioma 71%
  • Fluorescence 63%
  • protoporphyrin IX 44%
  • Heme 24%
  37 Scopus citations

• Niches that regulate stem cells and hematopoiesis in adult bone marrow

  Comazzetto, S., Shen, B. & Morrison, S. J., Jul 12 2021, In: Developmental cell. 56, 13, p. 1848-1860 13 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Leptin 100%
  • Stem Cell Niche 75%
  • Growth Factor 68%
  • Hematopoiesis 63%
  • Hematopoietic Stem Cells 57%
  100 Scopus citations

• Stable isotope tracing to assess tumor metabolism in vivo

  Faubert, B., Tasdogan, A., Morrison, S. J., Mathews, T. P. & DeBerardinis, R. J., Nov 2021, In: Nature Protocols. 16, 11, p. 5123-5145 23 p.

  Research output: Contribution to journal › Review article › peer-review

  • Stable Isotope 100%
  • Isotopes 98%
  • Metabolic 74%
  • Pharmacological Metabolism 70%
  • Isotope Labeling 66%
  30 Scopus citations
• 2020

  Cancer-associated fibroblasts: Versatile players in the tumor microenvironment

  Ganguly, D., Chandra, R., Karalis, J., Teke, M., Aguilera, T., Maddipati, R., Wachsmann, M. B., Ghersi, D., Siravegna, G., Zeh, H. J., Brekken, R., Ting, D. T. & Ligorio, M., Sep 2020, In: Cancers. 12, 9, p. 1-35 35 p., 2652.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Cancer-Associated Fibroblasts 100%
  • Tumor Microenvironment 74%
  • Neoplasms 10%
  • Physiological Adaptation 7%
  • Drug Approval 7%
  65 Scopus citations

• Establishment and function of chromatin modification at enhancers: Chromatin Landscape at Enhancers

  Tafessu, A. & Banaszynski, L. A., Oct 14 2020, In: Open Biology. 10, 10, 200255.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Enhancer 100%
  • Chromatin 74%
  • Modification 46%
  • Histone 36%
  • Histones 26%
  11 Scopus citations

• Metabolic reprogramming and cancer progression

  Faubert, B., Solmonson, A. & DeBerardinis, R. J., Apr 10 2020, In: Science. 368, 6487, eaaw5473.

  Research output: Contribution to journal › Review article › peer-review

  • Neoplasms 100%
  • Theoretical Models 27%
  • Therapeutics 11%
  955 Scopus citations

• Mitochondrial DNA Haplotypes as Genetic Modifiers of Cancer

  Tasdogan, A., McFadden, D. G. & Mishra, P., Dec 2020, In: Trends in Cancer. 6, 12, p. 1044-1058 15 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Mitochondrial DNA 100%
  • Haplotypes 89%
  • Mitochondria 78%
  • Mitochondrial Genome 59%
  • Reactive Oxygen Species 38%
  12 Scopus citations

• The PI3K–AKT network at the interface of oncogenic signalling and cancer metabolism

  Hoxhaj, G. & Manning, B. D., Feb 1 2020, In: Nature Reviews Cancer. 20, 2, p. 74-88 15 p.

  Research output: Contribution to journal › Review article › peer-review

  • Intercellular Signaling Peptides and Proteins 100%
  • Cell Survival 93%
  • Phosphatidylinositol 3-Kinase 83%
  • Cell Proliferation 54%
  • Neoplasms 52%
  1003 Scopus citations

• The roles of histone variants in fine-tuning chromatin organization and function

  Martire, S. & Banaszynski, L. A., Sep 1 2020, In: Nature Reviews Molecular Cell Biology. 21, 9, p. 522-541 20 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Histones 100%
  • Chromatin 94%
  • Chromatin Assembly and Disassembly 25%
  • Post Translational Protein Processing 21%
  • Histone Chaperones 16%
  194 Scopus citations
• 2019

  Mechanisms and Implications of Metabolic Heterogeneity in Cancer

  Kim, J. & DeBerardinis, R. J., Sep 3 2019, In: Cell Metabolism. 30, 3, p. 434-446 13 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Neoplasms 100%
  • Tumor Microenvironment 49%
  • Cellular Microenvironment 29%
  • Intrinsic Factor 29%
  • Glycolysis 25%
  323 Scopus citations

• The origins and functions of hepatic polyploidy

  Zhang, S., Lin, Y. H., Tarlow, B. & Zhu, H., Jun 18 2019, In: Cell Cycle. 18, 12, p. 1302-1315 14 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Polyploidy 100%
  • Liver 40%
  • Liver Diseases 7%
  • Regeneration 7%
  • Chromosomes 6%
  30 Scopus citations
• 2018

  Applications of metabolomics to study cancer metabolism

  Kaushik, A. K. & DeBerardinis, R. J., Aug 2018, In: Biochimica et Biophysica Acta - Reviews on Cancer. 1870, 1, p. 2-14 13 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Metabolomics 100%
  • Neoplasms 29%
  • Systems Biology 27%
  • Isotopes 24%
  • Mass Spectrometry 20%
  129 Scopus citations

• Lipoic acid metabolism and mitochondrial redox regulation

  Solmonson, A. & DeBerardinis, R. J., May 18 2018, In: Journal of Biological Chemistry. 293, 20, p. 7522-7530 9 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Lipoic Acid 100%
  • Thioctic Acid 95%
  • Pyruvate Dehydrogenase Complex 69%
  • Oxidation-Reduction 68%
  • Pharmacological Metabolism 55%
  218 Scopus citations

• Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications

  Fischer, G. M., Vashisht Gopal, Y. N., McQuade, J. L., Peng, W., DeBerardinis, R. J. & Davies, M. A., Jan 2018, In: Pigment Cell and Melanoma Research. 31, 1, p. 11-30 20 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Tumor Microenvironment 100%
  • Cell Communication 90%
  • Melanoma 79%
  • Metabolic 78%
  • Pharmacological Metabolism 49%
  123 Scopus citations

• Molecular mechanisms of cell death: Recommendations of the Nomenclature Committee on Cell Death 2018

  Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., Annicchiarico-Petruzzelli, M., Antonov, A. V., Arama, E., Baehrecke, E. H., Barlev, N. A., Bazan, N. G., Bernassola, F., Bertrand, M. J. M., Bianchi, K., Blagosklonny, M. V., & 149 othersBlomgren, K., Borner, C., Boya, P., Brenner, C., Campanella, M., Candi, E., Carmona-Gutierrez, D., Cecconi, F., Chan, F. K. M., Chandel, N. S., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Cohen, G. M., Conrad, M., Cubillos-Ruiz, J. R., Czabotar, P. E., D'Angiolella, V., Dawson, T. M., Dawson, V. L., De Laurenzi, V., De Maria, R., Debatin, K. M., Deberardinis, R. J., Deshmukh, M., Di Daniele, N., Di Virgilio, F., Dixit, V. M., Dixon, S. J., Duckett, C. S., Dynlacht, B. D., El-Deiry, W. S., Elrod, J. W., Fimia, G. M., Fulda, S., García-Sáez, A. J., Garg, A. D., Garrido, C., Gavathiotis, E., Golstein, P., Gottlieb, E., Green, D. R., Greene, L. A., Gronemeyer, H., Gross, A., Hajnoczky, G., Hardwick, J. M., Harris, I. S., Hengartner, M. O., Hetz, C., Ichijo, H., Jäättelä, M., Joseph, B., Jost, P. J., Juin, P. P., Kaiser, W. J., Karin, M., Kaufmann, T., Kepp, O., Kimchi, A., Kitsis, R. N., Klionsky, D. J., Knight, R. A., Kumar, S., Lee, S. W., Lemasters, J. J., Levine, B., Linkermann, A., Lipton, S. A., Lockshin, R. A., López-Otín, C., Lowe, S. W., Luedde, T., Lugli, E., MacFarlane, M., Madeo, F., Malewicz, M., Malorni, W., Manic, G., Marine, J. C., Martin, S. J., Martinou, J. C., Medema, J. P., Mehlen, P., Meier, P., Melino, S., Miao, E. A., Molkentin, J. D., Moll, U. M., Muñoz-Pinedo, C., Nagata, S., Nuñez, G., Oberst, A., Oren, M., Overholtzer, M., Pagano, M., Panaretakis, T., Pasparakis, M., Penninger, J. M., Pereira, D. M., Pervaiz, S., Peter, M. E., Piacentini, M., Pinton, P., Prehn, J. H. M., Puthalakath, H., Rabinovich, G. A., Rehm, M., Rizzuto, R., Rodrigues, C. M. P., Rubinsztein, D. C., Rudel, T., Ryan, K. M., Sayan, E., Scorrano, L., Shao, F., Shi, Y., Silke, J., Simon, H. U., Sistigu, A., Stockwell, B. R., Strasser, A., Szabadkai, G., Tait, S. W. G., Tang, D., Tavernarakis, N., Thorburn, A., Tsujimoto, Y., Turk, B., Vanden Berghe, T., Vandenabeele, P., Vander Heiden, M. G., Villunger, A., Virgin, H. W., Vousden, K. H., Vucic, D., Wagner, E. F., Walczak, H., Wallach, D., Wang, Y., Wells, J. A., Wood, W., Yuan, J., Zakeri, Z., Zhivotovsky, B., Zitvogel, L., Melino, G. & Kroemer, G., Mar 1 2018, In: Cell Death and Differentiation. 25, 3, p. 486-541 56 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Terminology 100%
  • Cell Death 75%
  • Parthanatos 20%
  • Ferroptosis 17%
  • Immunogenic Cell Death 17%
  3855 Scopus citations
• 2017

  Adult haematopoietic stem cell niches

  Crane, G. M., Jeffery, E. & Morrison, S. J., Sep 1 2017, In: Nature Reviews Immunology. 17, 9, p. 573-590 18 p.

  Research output: Contribution to journal › Review article › peer-review

  • Stem Cell Niche 100%
  • Adult Stem Cells 90%
  • Hematopoietic Stem Cells 76%
  • Maintenance 21%
  • Mesenchymal Stem Cells 13%
  474 Scopus citations

• Understanding the Intersections between Metabolism and Cancer Biology

  Vander Heiden, M. G. & DeBerardinis, R. J., Feb 9 2017, In: Cell. 168, 4, p. 657-669 13 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Pharmacological Metabolism 100%
  • Metabolic 70%
  • Neoplasms 41%
  • Chemical Transformation 27%
  • Biological Phenomena 25%
  1404 Scopus citations
• 2016

  Fundamentals of cancer metabolism

  DeBerardinis, R. J. & Chandel, N. S., May 2016, In: Science Advances. 2, 5, e1600200.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Neoplasms 100%
  • Oxidation-Reduction 59%
  • Energy Metabolism 56%
  • Carcinogenesis 47%
  • Neoplasm Metastasis 38%
  1849 Scopus citations

• Interfaces between mitochondrial dynamics and disease

  Mishra, P., Sep 2016, In: Cell Calcium. 60, 3, p. 190-198 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Mitochondrial Dynamics 100%
  • Mitochondrial Diseases 97%
  • Mitochondria 64%
  • Mitophagy 53%
  • Central Nervous System 28%
  29 Scopus citations

• Local production of astrocytes in the cerebral cortex

  Ge, W. P. & Jia, J. M., May 26 2016, In: Neuroscience. 323, p. 3-9 7 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Cerebral Cortex 100%
  • Astrocytes 98%
  • Neuroglia 76%
  • Lateral Ventricles 23%
  • Brain 10%
  42 Scopus citations
• 2015

  A roadmap for interpreting ¹³C metabolite labeling patterns from cells

  Buescher, J. M., Antoniewicz, M. R., Boros, L. G., Burgess, S. C., Brunengraber, H., Clish, C. B., DeBerardinis, R. J., Feron, O., Frezza, C., Ghesquiere, B., Gottlieb, E., Hiller, K., Jones, R. G., Kamphorst, J. J., Kibbey, R. G., Kimmelman, A. C., Locasale, J. W., Lunt, S. Y., Maddocks, O. D. K., Malloy, C., & 17 othersMetallo, C. M., Meuillet, E. J., Munger, J., Nöh, K., Rabinowitz, J. D., Ralser, M., Sauer, U., Stephanopoulos, G., St-Pierre, J., Tennant, D. A., Wittmann, C., Vander Heiden, M. G., Vazquez, A., Vousden, K., Young, J. D., Zamboni, N. & Fendt, S. M., Aug 1 2015, In: Current Opinion in Biotechnology. 34, p. 189-201 13 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Isotopic Tracer 100%
  • Metabolites 88%
  • Tracers 75%
  • Nutrient 69%
  • Biomedical Research 65%
  437 Scopus citations

• Designing a broad-spectrum integrative approach for cancer prevention and treatment

  Block, K. I., Gyllenhaal, C., Lowe, L., Amedei, A., Ruhul Amin, A. R. M., Amin, A., Aquilano, K., Arbiser, J., Arreola, A., Arzumanyan, A., Salman Ashraf, S., Azmi, A. S., Benencia, F., Bhakta, D., Bilsland, A., Bishayee, A., Blain, S. W., Block, P. B., Boosani, C. S., Carey, T. E., & 160 othersCarnero, A., Carotenuto, M., Casey, S. C., Chakrabarti, M., Chaturvedi, R., Chen, G. Z., Chen, H., Chen, S., Chen, Y. C., Choi, B. K., Ciriolo, M. R., Coley, H. M., Collins, A. R., Connell, M., Crawford, S., Curran, C. S., Dabrosin, C., Damia, G., Dasgupta, S., DeBerardinis, R. J., Decker, W. K., Dhawan, P., Diehl, A. M. E., Dong, J. T., Dou, Q. P., Drewa, J. E., Elkord, E., El-Rayes, B., Feitelson, M. A., Felsheru, D. W., Ferguson, L. R., Fimognari, C., Firestone, G. L., Frezza, C., Fujii, H., Fuster, M. M., Generali, D., Georgakilas, A. G., Gieseler, F., Gilbertson, M., Green, M. F., Grue, B., Guhal, G., Halicka, D., Helferich, W. G., Heneberg, P., Hentosh, P., Hirschey, M. D., Hofseth, L. J., Holcombe, R. F., Honoki, K., Hsu, H. Y., Huang, G. S., Jensen, L. D., Jiang, W. G., Jones, L. W., Karpowicz, P. A., Keith, W. N., Kerkar, S. P., Khan, G. N., Khatami, M., Ko, Y. H., Kucuk, O., Kulathinal, R. J., Kumar, N. B., Kwon, B. S., Leb, A., Leab, M. A., Lee, H. Y., Lichtor, T., Lin, L. T., Locasale, J. W., Lokeshwar, B. L., Longo, V. D., Lyssiotis, C. A., MacKenzie, K. L., Malhotra, M., Marino, M., Martinez-Chantar, M. L., Matheu, A., Maxwellx, C., McDonnell, E., Meeker, A. K., Mehrmohamadi, M., Mehta, K., Michelotti, G. A., Mohammad, R. M., Mohammed, S. I., Morre, D. J., Muqbil, I., Muralidharcq, V., Murphy, M. P., Nagaraju, G. P., Nahta, R., Niccolai, E., Nowsheen, S., Panis, C., Pantano, F., Parslow, V. R., Pawelec, G., Pedersen, P. L., Poore, B., Poudyal, D., Prakash, S., Prince, M., Raffaghello, L., Rathmell, J. C., Rathmell, W. K., Ray, S. K., Reichrath, J., Rezazadeh, S., Ribatti, D., Ricciardiello, L., Robeydf, R. B., Rodierdh, F., Rupasinghe, H. P. V., Russo, G. L., Ryan, E. P., Samadi, A. K., Sanchez-Garcia, I., Sanders, A. J., Santini, D., Sarkar, M., Sasada, T., Saxena, N. K., Shackelford, R. E., Shantha Kumara, H. M. C., Sharma, D., Shin, D. M., Sidransky, D., Siegelin, M. D., Signori, E., Singh, N., Sivanand, S., Sliva, D., Smythe, C., Spagnuolo, C., Stafforini, D. M., Stagg, J., Subbarayan, P. R., Sundin, T., Talib, W. H., Thompson, S. K., Tran, P. T., Ungefroren, H., Vander Heiden, M. G., Venkateswaran, V., Vinay, D. S., Vlachostergios, P. J., Wang, Z., Wellen, K. E., Whelan, R. L., Yang, E. S., Yang, H., Yang, X., Yaswen, P., Yedjou, C., Yin, X., Zhu, J. & Zollo, M., 2015, In: Seminars in Cancer Biology. 35, p. S276-S304

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Tumor Microenvironment 100%
  • Recurrence 82%
  • Neoplasms 62%
  • Genetic Heterogeneity 56%
  • Advisory Committees 51%
  250 Scopus citations

• Dysregulated metabolism contributes to oncogenesis

  Target Validation Team, Dec 1 2015, In: Seminars in Cancer Biology. 35, p. S129-S150

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Carcinogenesis 100%
  • Neoplasms 42%
  • Metabolic Networks and Pathways 32%
  • Epigenomics 28%
  • Tumor Suppressor Genes 16%
  219 Scopus citations

• In vivo analysis of lung cancer metabolism: Nothing like the real thing

  Hensley, C. T. & De Berardinis, R. J., Feb 2 2015, In: Journal of Clinical Investigation. 125, 2, p. 495-497 3 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Lung Neoplasms 100%
  • Neoplasms 40%
  • Metabolic Networks and Pathways 31%
  • Glucose 19%
  • Isotopes 17%
  17 Scopus citations

• Metabolic dysregulation in monogenic disorders and cancer-finding method in madness

  Erez, A. & Deberardinis, R. J., Jul 26 2015, In: Nature Reviews Cancer. 15, 7, p. 440-448 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Inborn Errors Metabolism 100%
  • Neoplasms 41%
  • Rare Diseases 25%
  • Cell Survival 19%
  • Mutation 14%
  83 Scopus citations

• Metabolic pathways promoting cancer cell survival and growth

  Boroughs, L. K. & Deberardinis, R. J., Apr 30 2015, In: Nature cell biology. 17, 4, p. 351-359 9 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Metabolic Networks and Pathways 100%
  • Cell Survival 75%
  • Growth 50%
  • Neoplasms 32%
  • Biosynthetic Pathways 30%
  1043 Scopus citations

• Ready, pause, go: Regulation of RNA polymerase II pausing and release by cellular signaling pathways

  Liu, X., Kraus, W. L. & Bai, X., Sep 1 2015, In: Trends in biochemical sciences. 40, 9, p. 516-525 10 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • RNA Polymerase II 100%
  • Protein 35%
  • Genes 34%
  • Proteins 31%
  • Molecule 29%
  102 Scopus citations
• 2014

  Cellular differences in protein synthesis regulate tissue homeostasis

  Buszczak, M., Signer, R. A. J. & Morrison, S. J., Oct 9 2014, In: Cell. 159, 2, p. 242-251 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Protein Synthesis 100%
  • Homeostasis 70%
  • Proteins 35%
  • Stem Cells 17%
  • Neoplasms 7%
  149 Scopus citations

• Immune modulation of stem cells and regeneration

  Aurora, A. B. & Olson, E. N., Jul 3 2014, In: Cell Stem Cell. 15, 1, p. 14-25 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Regeneration 100%
  • Stem Cells 87%
  • Immune System 63%
  • Immune Reconstitution 52%
  • Thromboplastin 44%
  224 Scopus citations

• Importance of breast cancer subtype in the development of androgen-receptor-directed therapy

  Lim, E., Ni, M., Cao, S., Hazra, A., Tamimi, R. M. & Brown, M., May 2014, In: Current Breast Cancer Reports. 6, 2, p. 71-78 8 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Androgen Receptors 100%
  • Breast Neoplasms 59%
  • Therapeutics 15%
  • Prostatic Neoplasms 12%
  • Clinical Trials 10%
  13 Scopus citations

• Mitochondrial dynamics and inheritance during cell division, development and disease

  Mishra, P. & Chan, D. C., Jan 1 2014, In: Nature Reviews Molecular Cell Biology. 15, 10, p. 634-646 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Mitochondrial Dynamics 100%
  • Mitochondrial Genes 98%
  • Organelles 74%
  • Cell Division 73%
  • Mitochondria 32%
  729 Scopus citations

• The bone marrow niche for haematopoietic stem cells

  Morrison, S. J. & Scadden, D. T., 2014, In: Nature. 505, 7483, p. 327-334 8 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Stem Cell Niche 100%
  • Hematopoietic Stem Cells 76%
  • Bone Marrow 56%
  • Hematopoiesis 28%
  • Cancellous Bone 27%
  1723 Scopus citations
• 2013

  Glutamine and cancer: Cell biology, physiology, and clinical opportunities

  Hensley, C. T., Wasti, A. T. & DeBerardinis, R. J., Sep 3 2013, In: Journal of Clinical Investigation. 123, 9, p. 3678-3684 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cell Physiological Phenomena 100%
  • Glutamine 82%
  • Cell Biology 67%
  • Nutrients 26%
  • Neoplasms 25%
  933 Scopus citations

• Mechanisms that regulate stem cell aging and life span

  Signer, R. A. J. & Morrison, S. J., Feb 7 2013, In: Cell Stem Cell. 12, 2, p. 152-165 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cellular Senescence 100%
  • Longevity 81%
  • Stem Cells 67%
  • Morbidity 21%
  • Neoplasms 17%
  259 Scopus citations

• Metabolism in physiological cell proliferation and differentiation

  Agathocleous, M. & Harris, W. A., Oct 2013, In: Trends in Cell Biology. 23, 10, p. 484-492 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cell Differentiation 100%
  • Cell Proliferation 81%
  • Metabolic Networks and Pathways 49%
  • Stem Cells 36%
  • Growth 24%
  173 Scopus citations

• Tumour heterogeneity and cancer cell plasticity

  Meacham, C. E. & Morrison, S. J., 2013, In: Nature. 501, 7467, p. 328-337 10 p.

  Research output: Contribution to journal › Review article › peer-review

  • Cell Plasticity 100%
  • Neoplastic Stem Cells 79%
  • Neoplasms 24%
  • High-Throughput Nucleotide Sequencing 23%
  • Disease Progression 19%
  1772 Scopus citations