Research output per year
Research output per year
- 1 - 50 out of 178 results
Search results
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2023
Light-activated macromolecular phase separation modulates transcription by reconfiguring chromatin interactions
Kim, Y. J., Lee, M., Lee, Y. T., Jing, J., Sanders, J. T., Botten, G. A., He, L., Lyu, J., Zhang, Y., Mettlen, M., Ly, P., Zhou, Y. & Xu, J., Mar 29 2023, In: Science Advances. 9, 13, eadg1123.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Neuron-binding antibody responses are associated with Black ethnicity in multiple sclerosis during natalizumab treatment
Telesford, K. M., Smith, C., Mettlen, M., Davis, M. B., Cowell, L., Kittles, R., Vartanian, T. & Monson, N., 2023, In: Brain Communications. 5, 4, fcad218.Research output: Contribution to journal › Article › peer-review
Open Access -
Neutrophil metabolomics in severe COVID-19 reveal GAPDH as a suppressor of neutrophil extracellular trap formation
Li, Y., Hook, J. S., Ding, Q., Xiao, X., Chung, S. S., Mettlen, M., Xu, L., Moreland, J. G. & Agathocleous, M., Dec 2023, In: Nature communications. 14, 1, 2610.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
ZNF692 organizes a hub specialized in 40S ribosomal subunit maturation enhancing translation in rapidly proliferating cells
Lafita-Navarro, M. C., Hao, Y. H., Jiang, C., Jang, S., Chang, T-C., Brown, I. N., Venkateswaran, N., Maurais, E., Stachera, W., Zhang, Y., Mundy, D. I., Han, J., Tran, V. M., Mettlen, M., Xu, L., Woodruff, J. B., Grishin, N. V., Kinch, L., Mendell, J. T., Buszczak, M., & 1 others, Oct 31 2023, In: Cell Reports. 42, 10, 113280.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2022
Simultaneous stabilization of actin cytoskeleton in multiple nephron-specific cells protects the kidney from diverse injury
Mukherjee, K., Gu, C., Collins, A., Mettlen, M., Samelko, B., Altintas, M. M., Sudhini, Y. R., Wang, X., Bouley, R., Brown, D., Pedro, B. P., Bane, S. L., Gupta, V., Brinkkoetter, P. T., Hagmann, H., Reiser, J. & Sever, S., Dec 2022, In: Nature communications. 13, 1, 2422.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
2020
An internally eGFP-tagged α-adaptin is a fully functional and improved fiduciary marker for clathrin-coated pit dynamics
Mino, R. E., Chen, Z., Mettlen, M. & Schmid, S. L., Sep 1 2020, In: Traffic. 21, 9, p. 603-616 14 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
DASC, a sensitive classifier for measuring discrete early stages in clathrin-mediated endocytosis
Wang, X., Chen, Z., Mettlen, M., Noh, J., Schmid, S. L. & Danuser, G., Apr 2020, In: eLife. 9, e53686.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein
Zhang, R., Lee, D. M., Jimah, J. R., Gerassimov, N., Yang, C., Kim, S., Luvsanjav, D., Winkelman, J., Mettlen, M., Abrams, M. E., Kalia, R., Keene, P., Pandey, P., Ravaux, B., Kim, J. H., Ditlev, J. A., Zhang, G., Rosen, M. K., Frost, A., Alto, N. M., & 5 others, Jun 1 2020, In: Nature cell biology. 22, 6, p. 674-688 15 p.Research output: Contribution to journal › Article › peer-review
Open Access57 Scopus citations -
Early and nonredundant functions of dynamin isoforms in clathrin-mediated endocytosis
Bhave, M., Mettlen, M., Wang, X. & Schmid, S. L., Aug 15 2020, In: Molecular biology of the cell. 31, 18, p. 2035-2047 13 p.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Functional characterization of 67 endocytic accessory proteins using multiparametric quantitative analysis of CCP dynamics
Bhave, M., Mino, R. E., Wang, X., Lee, J., Grossman, H. M., Lakoduk, A. M., Danuser, G., Schmid, S. L. & Mettlen, M., Dec 15 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 50, p. 31591-31602 12 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Immune checkpoint inhibition is safe and effective for liver cancer prevention in a mouse model of hepatocellular carcinoma
Chung, A. S., Mettlen, M., Ganguly, D., Lu, T., Wang, T., Brekken, R. A., Hsiehchen, D. & Zhu, H., Nov 1 2020, In: Cancer Prevention Research. 13, 11, p. 911-922 12 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
Wbox2: A clathrin terminal domain derived peptide inhibitor of clathrin-mediated endocytosis
Chen, Z., Mino, R. E., Mettlen, M., Michaely, P., Bhave, M., Reed, D. K. & Schmid, S. L., Sep 7 2020, In: Journal of Cell Biology. 219, 9, e201908189.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
2019
A nostalgic look back 40 years after the discovery of receptor-mediated endocytosis
Schmid, S. L., Jan 1 2019, In: Molecular biology of the cell. 30, 1, p. 1-3 3 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Cell type and receptor identity regulate cholera toxin subunit B (CTB) internalization
Sethi, A., Wands, A. M., Mettlen, M., Krishnamurthy, S., Wu, H. & Kohler, J. J., Apr 6 2019, In: Interface Focus. 9, 2, 20180076.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
Mutant p53 amplifies a dynamin-1/APPL1 endosome feedback loop that regulates recycling and migration
Lakoduk, A. M., Roudot, P., Mettlen, M., Grossman, H. M., Schmid, S. L. & Chen, P. H., Jun 3 2019, In: The Journal of cell biology. 218, 6, p. 1928-1942 15 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
The plos biology xv collection: 15 years of exceptional science highlighted across 12 months
Richardson, L. A., Schmid, S. L., Bhandoola, A., Harly, C., Hedenström, A., Laub, M. T., Mace, G. M., Sengupta, P., Stock, A. M., Read, A. F., Malik, H. S., Estelle, M., Lowell, S. & Kimmelman, J., Feb 2019, In: PLoS biology. 17, 2, e3000180.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2018
A noncanonical role for dynamin-1 in regulating early stages of clathrin-mediated endocytosis in non-neuronal cells
Srinivasan, S., Burckhardt, C. J., Bhave, M., Chen, Z., Chen, P. H., Wang, X., Danuser, G. & Schmid, S. L., Apr 18 2018, In: PLoS biology. 16, 4, e2005377.Research output: Contribution to journal › Article › peer-review
Open Access26 Scopus citations -
Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis article
Zhang, Z., Zi, Z., Lee, E. E., Zhao, J., Contreras, D. C., South, A. P., Abel, E. D., Chong, B. F., Vandergriff, T., Hosler, G. A., Scherer, P. E., Mettlen, M., Rathmell, J. C., DeBerardinis, R. J. & Wang, R. C., May 1 2018, In: Nature medicine. 24, 5, p. 617-627 11 p.Research output: Contribution to journal › Article › peer-review
Open Access107 Scopus citations -
Role for ERK1/2-dependent activation of FCHSD2 in cancer cell-selective regulation of clathrinmediated endocytosis
Xiao, G. Y., Mohanakrishnan, A. & Schmid, S. L., Oct 9 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 41, p. E9570-E9579Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
2017
A highly-sensitive high throughput assay for dynamin's basal GTPase activity
Mohanakrishnan, A., Tran, T. V. M., Kumar, M., Chen, H., Posner, B. A. & Schmid, S. L., Sep 2017, In: PloS one. 12, 9, e0185639.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Control of actin polymerization via the coincidence of phosphoinositides and high membrane curvature
Daste, F., Walrant, A., Holst, M. R., Gadsby, J. R., Mason, J., Lee, J. E., Brook, D., Mettlen, M., Larsson, E., Lee, S. F., Lundmark, R. & Gallop, J. L., Nov 1 2017, In: Journal of Cell Biology. 216, 11, p. 3745-3765 21 p.Research output: Contribution to journal › Article › peer-review
Open Access57 Scopus citations -
Crosstalk between CLCb/Dyn1-Mediated Adaptive Clathrin-Mediated Endocytosis and Epidermal Growth Factor Receptor Signaling Increases Metastasis
Chen, P. H., Bendris, N., Hsiao, Y. J., Reis, C. R., Mettlen, M., Chen, H. Y., Yu, S. L. & Schmid, S. L., Feb 6 2017, In: Developmental cell. 40, 3, p. 278-288.e5Research output: Contribution to journal › Article › peer-review
62 Scopus citations -
Decoupling global biases and local interactions between cell biological variables
Zaritsky, A., Obolski, U., Gan, Z., Reis, C. R., Kadlecova, Z., Du, Y., Schmid, S. L. & Danuser, G., Mar 13 2017, In: eLife. 6, e22323.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Reciprocal regulation of signaling and endocytosis: Implications for the evolving cancer cell
Schmid, S. L., Sep 1 2017, In: Journal of Cell Biology. 216, 9, p. 2623-2632 10 p.Research output: Contribution to journal › Article › peer-review
Open Access107 Scopus citations -
Regulation of clathrin-mediated endocytosis by hierarchical allosteric activation of AP2
Kadlecova, Z., Spielman, S. J., Loerke, D., Mohanakrishnan, A., Reed, D. K. & Schmid, S. L., 2017, In: Journal of Cell Biology. 216, 1, p. 167-179 13 p.Research output: Contribution to journal › Article › peer-review
Open Access110 Scopus citations -
TRAIL-death receptor endocytosis and apoptosis are selectively regulated by dynamin-1 activation
Reis, C. R., Chen, P. H., Bendris, N. & Schmid, S. L., Jan 17 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 3, p. 504-509 6 p.Research output: Contribution to journal › Article › peer-review
Open Access55 Scopus citations -
2016
Cell-Based Screen Identifies Human Interferon-Stimulated Regulators of Listeria monocytogenes Infection
Perelman, S. S., Abrams, M. E., Eitson, J. L., Chen, D., Jimenez, A., Mettlen, M., Schoggins, J. W. & Alto, N. M., Dec 21 2016, In: PLoS pathogens. 12, 12, e1006102.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Diagonally Scanned Light-Sheet Microscopy for Fast Volumetric Imaging of Adherent Cells
Dean, K. M., Roudot, P., Reis, C. R., Welf, E. S., Mettlen, M. & Fiolka, R., Mar 29 2016, In: Biophysical journal. 110, 6, p. 1456-1465 10 p.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
Identification and function of conformational dynamics in the multidomain GTPase dynamin
Srinivasan, S., Dharmarajan, V., Reed, D. K., Griffin, P. R. & Schmid, S. L., Feb 15 2016, In: EMBO Journal. 35, 4, p. 443-457 15 p.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
Ikarugamycin: A Natural Product Inhibitor of Clathrin-Mediated Endocytosis
Elkin, S. R., Oswald, N. W., Reed, D. K., Mettlen, M., MacMillan, J. B. & Schmid, S. L., Oct 1 2016, In: Traffic. 17, 10, p. 1139-1149 11 p.Research output: Contribution to journal › Article › peer-review
Open Access53 Scopus citations -
SNX9 promotes metastasis by enhancing cancer cell invasion via differential regulation of RhoGTPases
Bendris, N., Williams, K. C., Reis, C. R., Welf, E. S., Chen, P. H., Lemmers, B., Hahne, M., Leong, H. S. & Schmid, S. L., May 1 2016, In: Molecular biology of the cell. 27, 9, p. 1409-1419 11 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
Sorting nexin 9 negatively regulates invadopodia formation and function in cancer cells
Bendris, N., Stearns, C. J. S., Reis, C. R., Rodriguez-Canales, J., Liu, H., Witkiewicz, A. W. & Schmid, S. L., Jul 15 2016, In: Journal of cell science. 129, 14, p. 2804-2816 13 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
2015
A hemi-fission intermediate links two mechanistically distinct stages of membrane fission
Mattila, J. P., Shnyrova, A. V., Sundborger, A. C., Hortelano, E. R., Fuhrmans, M., Neumann, S., Müller, M., Hinshaw, J. E., Schmid, S. L. & Frolov, V. A., Aug 6 2015, In: Nature. 524, 7563, p. 109-113 5 p.Research output: Contribution to journal › Article › peer-review
76 Scopus citations -
A systematic analysis reveals heterogeneous changes in the endocytic activities of cancer cells
Elkin, S. R., Bendris, N., Reis, C. R., Zhou, Y., Xie, Y., Huffman, K. E., Minna, J. D. & Schmid, S. L., Nov 1 2015, In: Cancer research. 75, 21, p. 4640-4650 11 p.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
Crosstalk between Akt/GSK3β signaling and dynamin-1 regulates clathrin-mediated endocytosis
Reis, C. R., Chen, P. H., Srinivasan, S., Aguet, F., Mettlen, M. & Schmid, S. L., Aug 13 2015, In: EMBO Journal. 34, 16, p. 2132-2146 15 p.Research output: Contribution to journal › Article › peer-review
Open Access94 Scopus citations -
Fucosylation and protein glycosylation create functional receptors for cholera toxin
Wands, A. M., Fujita, A., McCombs, J. E., Cervin, J., Dedic, B., Rodriguez, A. C., Nischan, N., Bond, M. R., Mettlen, M., Trudgian, D. C., Lemoff, A., Quiding-Järbrink, M., Gustavsson, B., Steentoft, C., Clausen, H., Mirzaei, H., Teneberg, S., Yrlid, U. & Kohler, J. J., Oct 29 2015, In: eLife. 4, OCTOBER2015, e09545.Research output: Contribution to journal › Article › peer-review
Open Access72 Scopus citations -
2014
A Protein Kinase C Phosphorylation Motif in GLUT1 Affects Glucose Transport and is Mutated in GLUT1 Deficiency Syndrome
Lee, E. E., Ma, J., Sacharidou, A., Mi, W., Salato, V. K., Nguyen, N., Jiang, Y., Pascual, J. M., North, P. E., Shaul, P. W., Mettlen, M. & Wang, R. C., Nov 24 2014, In: Molecular cell. 58, 5, p. 845-853 9 p.Research output: Contribution to journal › Article › peer-review
96 Scopus citations -
Endocytosis: Past, Present, And future
Schmid, S. L., Sorkin, A. & Zerial, M., Dec 1 2014, In: Cold Spring Harbor Perspectives in Biology. 6, 12, a022509.Research output: Contribution to journal › Article › peer-review
41 Scopus citations -
Imaging and modeling the dynamics of clathrin-mediated endocytosis
Mettlen, M. & Danuser, G., Dec 1 2014, In: Cold Spring Harbor Perspectives in Biology. 6, 12, a017038.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
Intrapolypeptide Interactions between the GTPase Effector Domain (GED) and the GTPase Domain Form the Bundle Signaling Element in Dynamin Dimers
Srinivasan, S., Mattila, J. P. & Schmid, S. L., Sep 16 2014, In: Biochemistry. 53, 36, p. 5724-5726 3 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
2013
Advances in analysis of low signal-to-noise images link dynamin and AP2 to the functions of an endocytic checkpoint
Aguet, F., Antonescu, C., Mettlen, M., Schmid, S. & Danuser, G., Aug 12 2013, In: Developmental cell. 26, 3, p. 279-291 13 p.Research output: Contribution to journal › Article › peer-review
242 Scopus citations -
Analyzing membrane remodeling and fission using supported bilayers with excess membrane reservoir
Neumann, S., Pucadyil, T. J. & Schmid, S. L., Jan 2013, In: Nature Protocols. 8, 1, p. 213-222 10 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca2+ entry
Sharma, S., Quintana, A., Findlay, G. M., Mettlen, M., Baust, B., Jain, M., Nilsson, R., Rao, A. & Hogan, P. G., 2013, In: Nature. 499, 7457, p. 238-242 5 p.Research output: Contribution to journal › Article › peer-review
Open Access189 Scopus citations -
Dual role of BAR domain-containing proteins in regulating vesicle release catalyzed by the GTPase, dynamin-2
Neumann, S. & Schmid, S. L., Aug 30 2013, In: Journal of Biological Chemistry. 288, 35, p. 25119-25128 10 p.Research output: Contribution to journal › Article › peer-review
51 Scopus citations -
Dynamin-Catalyzed Membrane Fission Requires Coordinated GTP Hydrolysis
Liu, Y. W., Mattila, J. P. & Schmid, S. L., Jan 31 2013, In: PloS one. 8, 1, e55691.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Geometric catalysis of membrane fission driven by flexible dynamin rings
Shnyrova, A. V., Bashkirov, P. V., Akimov, S. A., Pucadyil, T. J., Zimmerberg, J., Schmid, S. L. & Frolov, V. A., Mar 22 2013, In: Science. 339, 6126, p. 1433-1436 4 p.Research output: Contribution to journal › Article › peer-review
Open Access114 Scopus citations -
Integrated Electron Microscopy: Super-Duper Resolution
Krijnse Locker, J. & Schmid, S. L., Aug 2013, In: PLoS biology. 11, 8, e1001639.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
2012
Context-Dependent Proangiogenic Function of Bone Morphogenetic Protein Signaling Is Mediated by Disabled Homolog 2
Kim, J. D., Kang, H., Larrivée, B., Lee, M. Y., Mettlen, M., Schmid, S. L., Roman, B. L., Qyang, Y., Eichmann, A. & Jin, S. W., Aug 14 2012, In: Developmental cell. 23, 2, p. 441-448 8 p.Research output: Contribution to journal › Article › peer-review
51 Scopus citations -
Structural Analysis of Dynamin Reveals a Mechanism of Membrane Fission
Hinshaw, J., Chappie, J. S., Mears, J. A., Fang, S., Leonard, M., Schmid, S. L., Milligan, R. A., Dyda, F. & Hinshaw, J. E., Jul 2012, In: Microscopy and Microanalysis. 18, p. 58-59 2 p.Research output: Contribution to journal › Article › peer-review
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Structural tuning of the fluorescent protein iLOV for improved photostability
Christie, J. M., Hitomi, K., Arvai, A. S., Hartfield, K. A., Mettlen, M., Pratt, A. J., Tainer, J. A. & Getzoff, E. D., Jun 22 2012, In: Journal of Biological Chemistry. 287, 26, p. 22295-22304 10 p.Research output: Contribution to journal › Article › peer-review
119 Scopus citations